A Model for the Magnetoimpedance Effect in Non-Symmetric Nanostructured Multilayered Films with Ferrogel Coverings

Abstract

Magnetoimpedance (MI) biosensors for the detection of in-tissue incorporated magnetic nanoparticles are a subject of special interest. The possibility of the detection of the ferrogel samples mimicking the natural tissues with nanoparticles was proven previously for symmetric MI thin-film multilayers. In this work, in order to describe the MI effect in non-symmetric multilayered elements covered by ferrogel layer we propose an electromagnetic model based on a solution of the 4Maxwell equations. The approach is based on the previous calculations of the distribution of electromagnetic fields in the non-symmetric multilayers further developed for the case of the ferrogel covering. The role of the asymmetry of the film on the MI response of the multilayer–ferrogel structure is analyzed in the details. The MI field and frequency dependences, the concentration dependences of the MI for fixed frequencies and the frequency dependence of the concentration sensitivities are obtained for the detection process by both symmetric and non-symmetric MI structures.

Biological Impact of γ-Fe2O3 Magnetic Nanoparticles Obtained by Laser Target Evaporation: Focus on Magnetic Biosensor Applications

“…LTE MNPs were used for hyperthermia, regenerative medicine, and magnetic ferrogel detection via magnetic field sensors [ 6 , 27 ]. The last detection case supported the next step from the single cell to the natural tissue state evaluation [ 38 ]. However, the biological activity of MNPs, using the primary cultures of human skin fibroblasts, are still underdeveloped.…”