A Modal Specification Approach for On-Demand Medical Systems

Abstract

The on-demand approach, where systems are assembled from components by lay users, has seen success in the consumer electronics industry. Currently, there is growing demand for on-demand capabilities in medical systems so caregivers can create larger medical systems from smaller medical devices. Unlike consumer electronics, medical systems pose challenges for the on-demand approach due to attributes such as device complexity, device variability and safety requirements. In this paper, we propose a formal specification language for on-demand (medical) systems. Our approach is based on the formalism of Modal I/O Automata, which allows system designers to express complex device requirements and can be used to reason about safety and liveness properties of on-demand medical systems directly from their specifications. We illustrate the applicability of our approach through a case study of a closed-loop patient controlled analgesia system. we propose a formal speci cation language for on-demand (medical) systems. Our approach is based on the formalism of Modal I/O Automata, which allows system designers to express complex device requirements and can be used to reason about safety and liveness properties of ondemand medical systems directly from their speci cations. We illustrate the applicability of our approach through a case study of a closed-loop patient controlled analgesia system.

A Treatment Validation Protocol for Cyber-Physical-Human Medical Systems

“…Some closed-loop control frameworks are proposed to mitigate safety hazards [2]. System modeling and formal verification are important issues for developing and analyzing medical systems [11]. King et al [11] proposed a formal specification language to express and reason safety properties of on-demand medical systems.…”

“…The following cases might occur: Case 1: Injecting sodium bicarbonate does not invalidate any precondition and successfully raises patient's blood pH value higher than 7.4. The system removes InjectSodiumBicarbonate 11 Sodium bicarbonate and calcium chloride cannot be simultaneously injected through the same IV pump, because they would form calcium carbonate and make the two drugs ineffective. node from the TPC tree and executes IncreaseIVFluid.…”

“…System modeling and formal verification are important issues for developing and analyzing medical systems [11]. King et al [11] proposed a formal specification language to express and reason safety properties of on-demand medical systems. Pajic et al combined simulation-based analysis and model checking to guarantee safety of closed-loop medical systems [15].…”

Assuring the safety of on-demand medical cyber-physical systems

“…A detailed exposition of the language (without timing specification) and its formal semantics is given in [13].…”