A MnFe2O4/C nanocomposite as a novel theranostic agent in MRI, sonodynamic therapy and photothermal therapy of a melanoma cancer model

Gorgizadeh, M.; Behzadpour, Niloufar; Salehi, Fatemeh; Daneshvar, Fatemeh; Vais, R. Dehdari; Nazari-Vanani, R.; Azarpira, Negar; Lotfi, Mehrzad; Sattarahmady, N.

doi:10.1016/j.jallcom.2019.152597

Cited by 33 publications

(13 citation statements)

References 56 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…[78] Besides, the MnFe 2 O 4 /C nanocomposites were also reported to exhibit the synergetic PTT/SDT treatment potential in deep tumor tissues. [79] With the deepening of the understanding of researchers on PTT, a number of second near-infrared (NIR-II)-window-based PTT have been explored and reported to have better therapeutic effects than those activated by the traditional NIR-I window light due to its greater maximum permissible exposure (MPE) and improved tissue penetration depth. [80] Correspondingly, better treatment output has been expected from the application of some nanoplatforms based on the combination of NIR-II window light activated-PTT and SDT.…”

Section: Sonodynamic Therapy Combined With Phototherapymentioning

confidence: 99%

Recent Advances in Nanomaterial‐Assisted Combinational Sonodynamic Cancer Therapy

et al. 2020

View full text Add to dashboard Cite

Ultrasound (US)-triggered sonodynamic therapy (SDT), as a promising noninvasive therapeutic modality, has received ever-increasing attention in recent years. Its specialized chemical agents, named sonosensitizers, are activated by low-intensity US to produce lethal reactive oxygen species (ROS) for oncotherapy. Compared with phototherapeutic strategies, SDT provides many noteworthy opportunities and benefits, such as deeper penetration depth, absence of phototoxicity, and fewer side effects. Nevertheless, previous studies have also demonstrated its intrinsic limitations. Thanks to the facile engineering nature of nanotechnology, numerous novel nanoplatforms are being applied in this emerging field to tackle these intrinsic barriers and achieve continuous innovations. In particular, the combination of SDT with other treatment strategies has demonstrated a superior efficacy in improving anticancer activity relative to that of monotherapies alone. Therefore, it is necessary to summarize the nanomaterial-assisted combinational sonodynamic cancer therapy applications. Herein, the design principles in achieving synergistic therapeutic effects based on nanomaterial engineering methods are highlighted. The ultimate goals are to stimulate the design of better-quality combined sonodynamic treatment schemes and provide innovative ideas for the perspectives of SDT in promoting its future transformation to clinical application.

show abstract

Section: Sonodynamic Therapy Combined With Phototherapymentioning

confidence: 99%

Recent Advances in Nanomaterial‐Assisted Combinational Sonodynamic Cancer Therapy

et al. 2020

View full text Add to dashboard Cite

show abstract

“…NiFe 2 O 4 @PAA composites (PAA -polyacrylic acid) could be considered as potential tracer agents for MPI, outperforming the commercial, commonly used tracer agents due to the minimum relaxation time of 3.10 μs and high resolution of 7.75 mT, [189]. Besides its use in photothermal and sonodynamic therapy of melanoma, MnFe 2 O 4 /C nanocomposite may also be used as a novel theranostic agent in nanomedicine [190]. In this regard, the intratumoral injection of MnFe 2 O 4 /C may induce deep tumor tissue necrosis, while the imaging studies endorse MnFe 2 O 4 /C as a contrast agent for MRI with a dose-dependent decrease in the signal intensity [189,190].…”

Section: Biomedical Applicationsmentioning

confidence: 99%

Characterization and Applications of Metal Ferrite Nanocomposites

2022

View full text Add to dashboard Cite

show abstract

“…They reported only a slight decrease in cell viability using the particles alone, or with NIR light exposure alone, or under US irradiation alone. However, the simultaneous combination of NIR light and US led to significant cytotoxicity and tumor necrosis [ 636 ].…”

Section: Reviewmentioning

confidence: 99%

Comprehensive review on ultrasound-responsive theranostic nanomaterials: mechanisms, structures and medical applications

Fateh¹,

Moradi²,

Kohan³

et al. 2021

Beilstein J. Nanotechnol.

View full text Add to dashboard Cite

The field of theranostics has been rapidly growing in recent years and nanotechnology has played a major role in this growth. Nanomaterials can be constructed to respond to a variety of different stimuli which can be internal (enzyme activity, redox potential, pH changes, temperature changes) or external (light, heat, magnetic fields, ultrasound). Theranostic nanomaterials can respond by producing an imaging signal and/or a therapeutic effect, which frequently involves cell death. Since ultrasound (US) is already well established as a clinical imaging modality, it is attractive to combine it with rationally designed nanoparticles for theranostics. The mechanisms of US interactions include cavitation microbubbles (MBs), acoustic droplet vaporization, acoustic radiation force, localized thermal effects, reactive oxygen species generation, sonoluminescence, and sonoporation. These effects can result in the release of encapsulated drugs or genes at the site of interest as well as cell death and considerable image enhancement. The present review discusses US-responsive theranostic nanomaterials under the following categories: MBs, micelles, liposomes (conventional and echogenic), niosomes, nanoemulsions, polymeric nanoparticles, chitosan nanocapsules, dendrimers, hydrogels, nanogels, gold nanoparticles, titania nanostructures, carbon nanostructures, mesoporous silica nanoparticles, fuel-free nano/micromotors.

show abstract

A MnFe2O4/C nanocomposite as a novel theranostic agent in MRI, sonodynamic therapy and photothermal therapy of a melanoma cancer model

Cited by 33 publications

References 56 publications

Recent Advances in Nanomaterial‐Assisted Combinational Sonodynamic Cancer Therapy

Recent Advances in Nanomaterial‐Assisted Combinational Sonodynamic Cancer Therapy

Characterization and Applications of Metal Ferrite Nanocomposites

Comprehensive review on ultrasound-responsive theranostic nanomaterials: mechanisms, structures and medical applications

Contact Info

Product

Resources

About