A miniaturized giant magnetic resistance system for quantitative detection of methamphetamine

Abstract

Point-of-care testing (POCT) systems have been greatly developed in recent years. Among them, lateral flow immunochromatography (LFIA) based on magnetic nanoparticles (MNPs) is widely used in various fields due to...

Magnetic nanoprobe-enabled lateral flow assays: recent advances

“…Furthermore, this device can be used to detect methamphetamine (MET) and morphine. 40,41 Thus, the initial examination of the disease can be performed quickly to ensure that the doctor can complete the corresponding diagnosis.…”

Highly Sensitive and Quantitative Magnetic Nanoparticle-Based Lateral Flow Immunoassay with an Atomic Magnetometer

“…4,5 Giant MR (GMR) and tunneling MR (TMR), the most representative MR sensors, offer high sensitivity approaches for immunomagnetic signal analysis. 2,6 However, large LFIA test strips are not well suited for MR sensors in POCT applications.…”

“…Numerous magnetic sensors, such as magnetoresistance (MR) and magnetic induction (MI) sensors, have demonstrated high accuracy and sensitivity in detecting LFIA strips. , Giant MR (GMR) and tunneling MR (TMR), the most representative MR sensors, offer high sensitivity approaches for immunomagnetic signal analysis. , However, large LFIA test strips are not well suited for MR sensors in POCT applications.…”

“…The analysis of diversified biomarkers with high sensitivity and in a point-of-care (POC) manner is significant for early cancer diagnosis. As a typical POC format, lateral flow immunoassay (LFIA) has been widely used in clinical diagnostics, food safety, and drug testing fields over recent decades. − However, the lack of test result precision and poor quantification confine its development in trace detection. Magnetic nanoparticles (MNPs), which exhibit excellent biocompatibility and stability, have served as LFIA labels for the biological detection of various substances and provide higher detection sensitivity. , Compared with the optical detection methods, magnetic LFIAs deliver quantitative measurement results by reading the magnetic signals of MNPs.…”