A micromagnetic actuator for biomolecule manipulation

Rostaing, Hervé; Chetouani, Hichem; Gheorghe, Marin; Galvin, Paul

doi:10.1016/j.sna.2006.08.012

Cited by 8 publications

(4 citation statements)

References 11 publications

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“…Thus, doubling the number of turns enables the component B Z of the field to be increased by 40%. These values are in good agreement with the results published in the literature (Rostaing et al 2007, Rida et al 2003. As the magnetic field created by circular coils is quite similar to that obtained with square coils, we simply give the maximal values of the components B X and B Z in table 3.…”

Section: Level Of Metallizationsupporting

confidence: 89%

Development of a flexible microfluidic system integrating magnetic micro-actuators for trapping biological species

Fulcrand¹,

Jugieu²,

Escriba³

et al. 2009

J. Micromech. Microeng.

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A flexible microfluidic system embedding microelectromagnets has been designed, modeled and fabricated by using a photosensitive resin as structural material. The fabrication process involves the integration of micro-coils in a multilayer SU-8 microfluidic system by combining standard electroplating and dry films lamination. This technique offers numerous advantages in terms of integration, biocompatibility and chemical resistance. Various designs of micro-coils, including spiral, square or serpentine wires, have been simulated and experimentally tested. It has been established that thermal dissipation in micro-coils depends strongly on the number of turns and current density but remains compatible with biological applications. Real-time experimentations show that these micro-actuators are efficient in trapping magnetic micro-beads without any external field source or a permanent magnet and highlight that the size of microfluidic channels has been adequately designed for optimal trapping. Moreover, we trap magnetic beads in less than 2 s and release them instantaneously into the micro-channel. The actuation solely relies on electric fields, which are easier to control than standard magneto-fluidic modules.

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Section: Level Of Metallizationsupporting

confidence: 89%

Development of a flexible microfluidic system integrating magnetic micro-actuators for trapping biological species

Fulcrand¹,

Jugieu²,

Escriba³

et al. 2009

J. Micromech. Microeng.

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show abstract

“…In MEMS fabrication, it is not feasible to directly electroplate permanent magnets but it is much easier to electroplate Ni. By electroplating certain structures of Ni and putting permanent magnets around to magnetize Ni, the micro manipulation chips can thus be made to control bio-particles [5,6]. The simple structure of such chip is modeled in figure 2: Figure 5 is the illustration of micro-manipulation chip.…”

Section: Modeling and Simulationmentioning

confidence: 99%

Bio-micro-manipulation Chip Based on Magneto-Archimedes Effect

Zhang

Mufeng

et al. 2011

2011 Third International Conference on Measuring Technology and Mechatronics Automation

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“…5a) as well as the flexcable based coil technology (Fig. 5b Rostaing et al (Tyndall National Institute, Cork, Ireland) developed a low cost system to attract and mix magnetic beads (7). The system uses microserpentine wires in combination with a permanent magnet to polarize the paramagnetic beads (Fig.…”

Section: Biomedical Devicesmentioning

confidence: 99%

(Invited) Active Magnetic Micro and Nano Electro-Mechnical Systems (MNEMS)

Gatzen¹

2011

ECS Trans.

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For active micro and nano electromechanical systems (MEMS/NEMS), electromagnetic actuators excel in robustness, are capable of substantial displacements, and of exerting rather large forces. This paper presents an overview over interesting micro and nano magnetic actuation activities in the range of optical devices, fluidic pump systems, biomedical applications, computer and communication technology devices, as well as X and X-Y actuation systems. Particular emphasis is put on research conducted in this field at the Leibniz Universitaet Hannover in Germany.

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A micromagnetic actuator for biomolecule manipulation

Cited by 8 publications

References 11 publications

Development of a flexible microfluidic system integrating magnetic micro-actuators for trapping biological species

Development of a flexible microfluidic system integrating magnetic micro-actuators for trapping biological species

Bio-micro-manipulation Chip Based on Magneto-Archimedes Effect

(Invited) Active Magnetic Micro and Nano Electro-Mechnical Systems (MNEMS)

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