A meta-analysis of psychotherapy and medication in unipolar depression and dysthymia

Imel, Zac E.; Malterer, Melanie B.; McKay, Kevin; Wampold, Bruce E.

doi:10.1016/j.jad.2008.03.018

Cited by 127 publications

(92 citation statements)

References 48 publications

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“…Other studies point to a similar direction. 28,29 Still, mixing acute and persistent forms of minor depression may have masked important clinical variation, as responsiveness to psychotherapeutic treatments is likely to vary according to the persistence of symptoms. 18 When interpreting our findings, it must be kept in mind that 5 of the 6 trials focusing on dysthymia or minor depression in our meta-analysis investigated problem-solving therapy.…”

Section: Comparison With Other Studiesmentioning

confidence: 99%

Effectiveness of Psychological Treatments for Depressive Disorders in Primary Care: Systematic Review and Meta-Analysis

Linde

Sigterman

Kriston

et al. 2015

The Annals of Family Medicine

172

112

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PURPOSE We performed a systematic review of the currently available evidence on whether psychological treatments are effective for treating depressed primary care patients in comparison with usual care or placebo, taking the type of therapy and its delivery mode into account. METHODSRandomized controlled trials comparing a psychological treatment with a usual care or a placebo control in adult, depressed, primary care patients were identified by searches in MEDLINE, Embase, Cochrane Central Register of Controlled Trials (CENTRAL), and PsycINFO up to December 2013. At least 2 reviewers extracted information from included studies and assessed the risk of bias. Random effects meta-analyses were performed using posttreatment depression scores as outcome. RESULTSA total of 30 studies with 5,159 patients met the inclusion criteria. Compared with control, the effect (standardized mean difference) at completion of treatment was -0.30 (95% CI, -0.48 to -0.13) for face-to-face cognitive behavioral therapy (CBT), -0.14 (-0.40 to 0.12) for face-to-face problem-solving therapy, -0.24 (-0.47 to -0.02) for face-to-face interpersonal psychotherapy, -0.28 (-0.44 to -0.12) for other face-to-face psychological interventions, -0.43 (-0.62 to -0.24) for remote therapist-led CBT, -0.56 (-1.57 to 0.45) for remote therapist-led problem-solving therapy, -0.40 (-0.69 to -0.11) for guided selfhelp CBT, and -0.27 (-0.44 to -0.10) for no or minimal contact CBT.CONCLUSIONS There is evidence that psychological treatments are effective in depressed primary care patients. For CBT approaches, substantial evidence suggests that interventions that are less resource intensive might have effects similar to more intense treatments.

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Section: Comparison With Other Studiesmentioning

confidence: 99%

Effectiveness of Psychological Treatments for Depressive Disorders in Primary Care: Systematic Review and Meta-Analysis

Linde

Sigterman

Kriston

et al. 2015

The Annals of Family Medicine

172

112

View full text Add to dashboard Cite

show abstract

“…Several comparator trials and meta-analyses have attempted to compare antidepressants and psychotherapy to determine which might provide more symptom relief, typically using clinician-rated symptom inventories such as the Hamilton Rating Scale for Depression (HRSD). By and large, the results of these meta-analyses indicate that short-term acute treatment of major depressive disorder yields equivalent results on average between pharmacotherapy and psychotherapy (Casacalenda et al, 2002;Cuijpers et al, 2008Cuijpers et al, , 2013aHuhn et al, 2014;Imel et al, 2008;Spielmans et al, 2011), and pharmacological treatment may be superior to psychotherapy in the treatment of dysthymia (Cuijpers et al, 2008(Cuijpers et al, , 2013bImel et al, 2008). Further, a meta-analysis of trials comparing psychotherapy to pill placebo (Cuijpers et al, 2014b) yielded an overall therapy-placebo effect size comparable to the effect sizes found in meta-analyses of antidepressant-placebo differences (Kirsch et al, 2008;Sugarman et al, 2014;Turner et al, 2008).…”

mentioning

confidence: 64%

“…Outcomes were roughly equivalent when comparing cognitive behavioral therapy to continued pharmacotherapy. Imel et al (2008) also found that psychotherapy yielded superior results compared to pharmacotherapy at long-term follow-up with an average interval of 15 months. Moreover, length of follow-up was a significant moderator such that the advantage of psychotherapy over medication was superior at longer follow-up intervals.…”

mentioning

confidence: 87%

Are antidepressants and psychotherapy equally effective in treating depression? A critical commentary

Sugarman

2016

Journal of Mental Health

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“…The main features of depression include a period of at least two weeks of depressed mood, loss of interest or lack of joy. Moreover, The person must have at least a few other symptoms including changes in appetite or weight, sleep and psychomotor tasks, reducing power, feelings of worthlessness or guilt, difficulty in thinking, decentralization in decision-making, recurrent thoughts of death and suicide, planning or attempt for suicide (Imel et al, 2008). Depression is a common disease in the world with the debilitating effect (Lopez et al, 2006).…”

Section: Introductionmentioning

confidence: 99%

Effectiveness of Group Schema Therapy in Reducing the Symptoms of Major Depression in a Sample of Women

Hashemi¹,

Darvishzadeh²

2016

ASS

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Treatment of the symptoms of major depression is one of the important issues in the treatment of psychological disorders. This study aims to investigate effectiveness of group schema therapy in reducing the symptoms of major depression in a sample of women in the Ahvaz City. This is a quasi-experimental with two control and treatment groups. To this end, 30 married women in Ahvaz were selected using the convenience sampling method and were included in two treatment and control groups of 15 persons. After pre-test for both groups, the experimental group received schema therapy in 10 sessions for one month; however, the control group received no training. Beck Depression Inventory that has an acceptable reliability and validity was used to assess depression. Finally, test scores were analyzed by analysis of covariance. The results showed that group schema therapy training was effective at the level of error P<0.0001 on reducing the symptoms of depression in the treatment group. Accordingly, it can be concluded that the group schema therapy training affects the mental health promotion. Therefore, the intervention can be effective in preventing mental injuries.

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A meta-analysis of psychotherapy and medication in unipolar depression and dysthymia

Cited by 127 publications

References 48 publications

Effectiveness of Psychological Treatments for Depressive Disorders in Primary Care: Systematic Review and Meta-Analysis

Effectiveness of Psychological Treatments for Depressive Disorders in Primary Care: Systematic Review and Meta-Analysis

Are antidepressants and psychotherapy equally effective in treating depression? A critical commentary

Effectiveness of Group Schema Therapy in Reducing the Symptoms of Major Depression in a Sample of Women

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