A low-cost potentiostat for point-of-need diagnostics

Bezuidenhout, Petrone; Smith, Suzanne; Land, Kevin; Joubert, Trudi-Heleen

doi:10.1109/afrcon.2017.8095460

Cited by 16 publications

(13 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…2018, 8, x 3 of 12 [33] on the open-source Arduino [29] was selected for the development of the low-cost point-ofneed potentiostat. A potentiostat front-end was manufactured on a paper substrate and compared to a prototype of the device manufactured on a printed circuit board (PCB), an off-the-shelf potentiostat front-end development board, and a laboratory-based potentiostat instrument [14,15]. Cyclic voltammetry was performed using a 5 mM ferri-ferrocyanide 80 µL sample dropped onto a commercial screenprinted electrode.…”

Section: Materials and Manufacturingmentioning

confidence: 99%

“…The 2.5 V reference voltage (V ref ) created the internal zero around 1.25 V, as well as a voltage range of 1.2 V containing 48 steps, which generates an input voltage step size of 25 mV. Therefore, a 50 mVs −1 scan rate is achieved by stepping once every 500 ms [14]. The voltage output signal (V out ) of the sensing chip is translated to the output current (I out ) using Equation (1) [31].…”

Section: Design and Development Of The Potentiostatmentioning

confidence: 99%

See 1 more Smart Citation

A Low-Cost Inkjet-Printed Paper-Based Potentiostat

2018

View full text Add to dashboard Cite

Featured Application: An electrochemical reader developed with the aim to create a low-cost disposable, maintenance-free and user-friendly point-of-need sensing system. Abstract:The work presented details the manufacturing of a low-cost hybrid inkjet-printed paper-based potentiostat, with the aim of creating a low-cost sensing system for rapid water quality monitoring. Potentiostats exhibit high sensitivities and can be used for a variety of applications. The results highlight the functionality of a paper-based potentiostat compared to a potentiostat manufactured on a printed circuit board (PCB), an LMP91000EVM development board and a laboratory-based Metrohm Autolab potentiostat. Cyclic voltammetry was performed using an 80 µL sample of 5 mM ferri-ferrocyanide dropped onto a commercial screen-printed electrode from DropSens. The miniaturized paper-based potentiostat is small enough to be stored in a wallet and therefore easy to transport. Furthermore, a cost analysis shows that the potentiostat is 10 times lower in cost than the commercially available handheld potentiostat, taking the costs of man hours into account. This technology enables electrochemistry experiments to be performed on-site using the portable, disposable and low-cost solution and can be applied to a variety of fields including healthcare, wearables and environmental monitoring.

show abstract

Section: Materials and Manufacturingmentioning

confidence: 99%

Section: Design and Development Of The Potentiostatmentioning

confidence: 99%

A Low-Cost Inkjet-Printed Paper-Based Potentiostat

2018

View full text Add to dashboard Cite

show abstract

“…Such aptamer-based biosensors require pulse voltammetry techniques like square wave voltammetry (SWV) [13] to obtain the necessary sensitivity to accurately quantify the signal produced by the aptamer upon binding to the analyte. 2 of 12 Due to the growing popularity of electrochemical biosensors, numerous in-house potentiostats have been presented in the literature [9,[14][15][16][17][18][19][20][21][22][23][24][25][26][27]. Such designs aim to decrease the cost and increase the accessibility of potentiostats with the goal of democratizing scientific research or to miniaturize electrochemistry hardware for use in at-home or portable diagnostic devices.…”

Section: Introductionmentioning

confidence: 99%

“…The LMP91000's integrated features allow for basic electrochemical techniques such as cyclic voltammetry (CV) and chronoamperometry (CA) used in lactate and glucose sensors, but lack sufficient voltage reference generators to perform more complex voltammetric techniques like SWV and normal pulsed voltammetry (NPV). Some designs have leveraged the LMP91000 [7,14,[22][23][24][25][26]31,32], but have limited voltage reference generators and limited, if any, on-chip signal-processing capabilities.…”

Section: Introductionmentioning

confidence: 99%

KickStat: A Coin-Sized Potentiostat for High-Resolution Electrochemical Analysis

Hoilett

Walker

Balash

et al. 2020

Sensors

View full text Add to dashboard Cite

The demand for wearable and point-of-care devices has led to an increase in electrochemical sensor development to measure an ever-increasing array of biological molecules. In order to move from the benchtop to truly portable devices, the development of new biosensors requires miniaturized instrumentation capable of making highly sensitive amperometric measurements. To meet this demand, we have developed KickStat, a miniaturized potentiostat that combines the small size of the integrated Texas Instruments LMP91000 potentiostat chip (Texas Instruments, Dallas, TX, USA) with the processing power of the ARM Cortex-M0+ SAMD21 microcontroller (Microchip Technology, Chandler, AZ, USA) on a custom-designed 21.6 mm by 20.3 mm circuit board. By incorporating onboard signal processing via the SAMD21, we achieve 1 mV voltage increment resolution and an instrumental limit of detection of 4.5 nA in a coin-sized form factor. This elegant engineering solution allows for high-resolution electrochemical analysis without requiring extensive circuitry. We measured the faradaic current of an anti-cocaine aptamer using cyclic voltammetry and square wave voltammetry and demonstrated that KickStat's response was within 0.6% of a high-end benchtop potentiostat. To further support others in electrochemical biosensors development, we have made KickStat's design and firmware available in an online GitHub repository.

show abstract

“…In order to analyse and process the information from sensor electrodes, potentiostat is used. Due to the available commercialize potentiostat are expensive, bulky and often exceed the practical needs, researchers tends to build its own using existing information [9]- [16]. Thus, the purpose of this study is to describe the development of a potentiostat device for the purposed of HMI detection.…”

Section: Introductionmentioning

confidence: 99%

A Low Cost Potentiostat Device For Monitoring Aqueous Solution

et al. 2018

View full text Add to dashboard Cite

This study developed a new design of a low cost potentiostat circuit device. This device is an alternative electrochemical instrument applied for monitoring heavy metal ion in environmental water. It was developed to alleviate the cost burden of equipment procurement and due to the requirement for in-situ application since the existing commercialize devices are bulky and expensive. The main component of the device consist of electronics configuration of operational amplifier. The device was first modelled and simulated to acquire the design parameters and performance. The potential control algorithm was developed on open-source microcontroller platform. A dummy cell was used to validate the capabilities of the device.

show abstract

A low-cost potentiostat for point-of-need diagnostics

Cited by 16 publications

References 14 publications

A Low-Cost Inkjet-Printed Paper-Based Potentiostat

A Low-Cost Inkjet-Printed Paper-Based Potentiostat

KickStat: A Coin-Sized Potentiostat for High-Resolution Electrochemical Analysis

A Low Cost Potentiostat Device For Monitoring Aqueous Solution

Contact Info

Product

Resources

About