A Liquid Chromatographic Method for Analysis of AU-Rac-α-Tocopheryl Acetate and Retinyl Palmitate in Medical Food Using Matrix Solid-Phase Dispersion in Conjunction with a Zero Reference Material as a Method Development Tool
Abstract:A liquid chromatographic method is described for analysis of all-rac-α-tocopheryl acetate and retinyl palmitate in medical food. The vitamins are extracted from medical food without saponification by matrix solid-phase dispersion and chromatographed by normal-phase chromatography with fluorescence detection. Retinyl palmitate and all-rac-α-tocopheryl acetate are quantitated isocratically with a mobile phase of 0.125% (v/v) and 0.5% (v/v) isopropyl alcohol in hexane, respectively. Results compared favorably wit… Show more
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