A light adjustable lens with injectable optics

Olson, Randall J.; Mamalis, Nick; Haugen, Brian

doi:10.1097/01.icu.0000193073.17122.ba

Cited by 14 publications

(9 citation statements)

References 8 publications

(6 reference statements)

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“…Lens refilling carries the potential of fully restoring accommodation due to the great impact of changes in optic curvature on the refractive power. Also, light-adjustable devices may potentially be designed that allow for fine-tuning of the residual refractive error following polymerization [66]. Apart from appropriate filling materials and techniques, however, aftercataract prevention is still the major problem.…”

Section: Conclusion and Future Perspectivesmentioning

confidence: 99%

Accommodating intraocular lenses: a critical review of present and future concepts

Menapace

Findl

Kriechbaum

et al. 2006

Graefe's Arch Clin Exp Ophthalmol

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As opposed to psychophysical evaluation techniques, laser interferometry measures what shift lenses are designed to provide: axial shift on accommodative effort. While under pilocarpine some movement was recorded, no movement at all was found under near-point stimulation with any of the lenses currently marketed. In contrast, magnetic-driven active-shift lens systems carry the potential of sufficiently topping up apparent accommodation to provide for clinically useful accommodation while using conventional lens designs with proven after-cataract performance. Dual optic implants significantly increase the impact of axial optic shift. The main potential problem, however, is delayed formation of interlenticular regenerates. Lens refilling procedures offer the potential of fully restoring accommodation due to the great impact of increase in surface curvature on refractive lens power. However, various problems remain to be solved before clinical use can be envisaged, above all, again, after-cataract prevention. The concept of passive single-optic shift lenses has failed. Concomitant poor capsular bag performance makes these lenses an unacceptable trade-off. Magnet-assisted systems potentially combine clinically useful accommodation with satisfactory after-cataract performance. Dual optic lenses theoretically offer substantial accommodative potential but may allow for interlenticular after-cataract formation. Lens refilling procedures have the greatest potential for fully restoring natural accommodation, but will again require years of extensive laboratory and animal investigations before they may function in the human eye.

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Section: Conclusion and Future Perspectivesmentioning

confidence: 99%

Accommodating intraocular lenses: a critical review of present and future concepts

Menapace

Findl

Kriechbaum

et al. 2006

Graefe's Arch Clin Exp Ophthalmol

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show abstract

“…optical correlators). Low‐cost, customizable recording of arbitrary DOEs, as has been demonstrated in photopolymers, is of interest for endoscopic probes, contact lenses and intraocular lenses (including UV recording of custom index profiles in vivo after implantation).…”

Section: Applications and Design Specificationsmentioning

confidence: 99%

Design concepts for diffusive holographic photopolymers

Kowalski

McLeod

2016

J Polym Sci B Polym Phys

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Diffusive photopolymers are an area of intense recent materials development, spurred by interest in holographic data storage, display holography, and custom diffractive optical elements, among other applications. This review examines a range of photopolymer formulations of academic and commercial interest, and places their design strategies in context via quantitative analysis of the recording fidelity, maximum refractive index change and the degree to which they achieve this limit. Finally, this analysis is extended to estimate the scope of achievable future performance improvements. © 2016 Wiley Periodicals, Inc. J. Polym. Sci., Part B: Polym. Phys. 2016, 54, 1021–1035.

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“…Thus for some patients an enhancement procedure such as corneal refractive surgery may be required. One way of avoiding this would be a method for changing the power of the IOL after it is implanted: the light‐adjustable lens (LAL) provides such a method …”

Section: Static (Passive) Methods: Increasing Binocular Depth‐of‐focusmentioning

confidence: 99%

Developments in the correction of presbyopia II: surgical approaches

Charman

2014

Ophthalmic Physiologic Optic

113

109

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Purpose: To discuss the various static and dynamic surgical approaches which attempt to give presbyopes good vision at far, intermediate and near viewing distances. Content: Static methods broadly adopt the same optical techniques as those used in presbyopic contact lens correction and aim to satisfy the needs of the presbyope by increasing binocular depth-of-focus, often using monovision as well as simultaneous-imagery. Dynamic methods generally attempt to make use of at least some of the still-active elements of the accommodation system. They include procedures which are supposed to modify the relative geometry of the ciliary muscle and lens, or which reduce the stiffness of the presbyopic lens either by replacing it with other natural or man-made material or by subjecting it to femtosecond laser treatment. Alternatively the natural lens may be replaced by some form of intraocular lens which changes power as a result of forces derived from the still-active ciliary muscle, zonule and capsule, or other sources. Conclusions: At present, multifocal intraocular lenses appear to offer the most consistent and reliable surgical approach to surgical presbyopic correction. They have obvious advantages in convenience and stability over optically-similar, simultaneous-image presbyopic contact lenses but this must be balanced against their relative inflexibility in cases of patient dissatisfaction. Dynamic methods remain largely experimental. Although some approaches show promise, as yet no method has demonstrated a reliable, long-term ability to correct distance refractive error and to appropriately change ocular power in response to changes in viewing distance over the normal range of interest.

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A light adjustable lens with injectable optics

Cited by 14 publications

References 8 publications

Accommodating intraocular lenses: a critical review of present and future concepts

Accommodating intraocular lenses: a critical review of present and future concepts

Design concepts for diffusive holographic photopolymers

Developments in the correction of presbyopia II: surgical approaches

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