A Large Extragnathic Keratocystic Odontogenic Tumour

Odontogenic keratocysts make up 4%–12% of all odontogenic cysts. Most cysts are sporadic but sometimes they arise in the context of basal cell nevus syndrome (Gorlin syndrome). Most odontogenic keratocysts arise in the posterior region of the mandible, but they can occur anywhere in the jaw. In rare instances, they are located peripherally in the gingiva. Even more rare, they are found in the soft tissues of the mouth. There have been a few case reports and small case series of such peripheral odontogenic keratocysts. Some controversy exists as to whether these truly represent a peripheral counterpart of the intraosseous odontogenic keratocysts and if their origin is at all odontogenic. We hereby present two cases of peripheral odontogenic keratocysts, both being located in the soft tissue of the buccal mucosa, and review the literature on peripheral odontogenic keratocysts.

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“…Most of these involve the gingiva, but mucosal, epidermal and even intramuscular sites have also been described (Table 1). 2–9…”

Section: Introductionmentioning

confidence: 99%

Odontogenic keratocysts located in the buccal mucosa: A description of two cases and review of the literature

Witteveen

Flores

Karssemakers

et al. 2019

SAGE Open Medical Case Reports

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“…OKCs are characterised by an aggressive behaviour with a relatively high recurrence rate, particularly when OKCs are associated with syndromes. The mitotic activity is higher than other cysts of odontogenic origin 5,6 .…”

Section: Introductionmentioning

confidence: 75%

Cystic lesions of the jaws: 13 years experience

Dhanrajani¹,

Smith²

2020

Oral Surgery

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Objective Cysts of the mouth and jaws are common, and their management is an essential component of oral surgery. Patients may present with symptoms though more frequently they are asymptomatic and are referred as a result of incidental finding by a dentist. This retrospective study reviews the clinical presentation, radiologic features, management and outcomes of jaw cysts treated by a single oral surgeon between 2005 and 2018. Methods Medical records were reviewed for data on diagnosis, pathology, treatment modalities and follow‐up outcomes among the patients. The principal emphasis is to report the outcome of odontogenic keratocytes managed conservatively in relation to recent World Health Organization classification. Results Records of 214 patients having a true cystic jaw lesion were reviewed. The most common cystic lesions were radicular cyst (38%) followed by dentigerous cysts (36%) and odontogenic keratocyst (OKC) (10%). Fifty‐six percent (56 of 214) of all cystic lesions were asymptomatic on presentation and were identified by imaging. All patients underwent surgical intervention, including biopsy, enucleation and/or curettage as indicated. Cases were treated principally by enucleation. None of 214 cases showed any recurrence. Marsupialisation was the treatment for seven cases of eruption cyst and two cases of dentigerous cyst associated with erupting teeth in children. Conclusions Jaw cysts are not unusual, many of these cysts are asymptomatic and are identified incidentally on orthopantomography. Radicular cyst was the most common followed by dentigerous cyst and OKC. All the patients were treated successfully with surgical intervention and none showed any recurrence.

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“…Follow-up is available for 18 reported POKC and shows a low recurrence rate (3 cases – 17%), whereas the remaining 15 cases (83%) did not show any evidence of local recurrence in a mean of 27 months of follow-up ( Table 1 , Table 1 cont.) ( 3 , 6 , 9 - 12 , 14 , 16 - 19 , 22 - 24 ). Case 1 has been followed-up for 48 months with no signs of local recurrence.…”

Section: Discussionmentioning

confidence: 99%

Peripheral odontogenic keratocyst: Report of two new cases and review of the literature

Rodrigues¹,

Israel²,

Moura³

et al. 2020

J Clin Exp Dent

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Peripheral odontogenic keratocyst (POKC) is a rare soft tissue entity showing the same histological characteristics of odontogenic keratocyst. Herein, we report two cases of POKC affecting the gingiva/alveolar mucosa. Case 1. A 43-year-old female was referred for evaluation of a painless well-defined nodular, sessile, non-tender swelling in the right maxillary buccal gingiva. No radiological alterations were observed. The patient was submitted to excisional biopsy and histological diagnosis was POKC. There were no signs of local recurrence after a 4-year follow-up. Case 2. A 63-year-old female was referred for evaluation of a painless well-defined nodular, sessile, yellowish swelling in the anterior mandibular alveolar mucosa. No radiological alterations were observed. The patient was submitted to excisional biopsy and histological diagnosis was POKC. Patient recovery was uneventful but she did not return for follow-up. POKC should be considered in the differential diagnosis of gingival cystic swellings and can be managed through conservative surgery. Key words: Odontogenic keratocyst, peripheral, gingiva, alveolar mucosa.

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A Large Extragnathic Keratocystic Odontogenic Tumour

Cited by 12 publications

References 22 publications

Odontogenic keratocysts located in the buccal mucosa: A description of two cases and review of the literature

Odontogenic keratocysts located in the buccal mucosa: A description of two cases and review of the literature

Cystic lesions of the jaws: 13 years experience

Peripheral odontogenic keratocyst: Report of two new cases and review of the literature

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