A label-free impedimetric sensor for the detection of an amphetamine-type derivative based on cucurbit[7]uril-mediated three-dimensional AuNPs

Emerging sensing platforms based on Cucurbit[n]uril functionalized gold nanoparticles and electrodes

“…The 3D-Au NPs@CB [7]-modified electrodes exhibit 63 times signal enhancement compared to direct CB [7] modified electrodes. 72 Based on this strategy, we recently prepared CB [7]-mediated 3D Au NP assemblies for the detection of aromatic amino acids. 73 In the electrochemical experiments, both the size of the Au NPs and the volume of 3D Au NP assemblies significantly influence the sensitivity.…”

Integration of Smart Nanomaterials for Highly Selective Disposable Sensors and Their Forensic Applications in Amphetamine Determination

“…Several strategies, such as derivatization or sample pre-treatment, are helpful for lab base testing but not practical for field applications, which allow only qualitative determinations. Alternatively, generic macrocycles and polymers have been used to determine amphetamine using impedance, capacitance, and field-effect transistors [64][65][66]. These are unsuitable for on-field applications due to the lack of selectivity and matrix effect.…”