A label-free aptasensor based on polyethyleneimine wrapped carbon nanotubes in situ formed gold nanoparticles as signal probe for highly sensitive detection of dopamine

Azadbakht, Azadeh; Roushani, Mahmoud; Abbasi, Amir Reza; Menati, Saeid; Derikvand, Zohreh

doi:10.1016/j.msec.2016.05.077

Cited by 43 publications

(21 citation statements)

References 43 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For this purpose, aptamer‐based electrochemical biosensors are most popular. Most aptamer‐based electrochemical biosensors are made up of three parts consisting of a DNA aptamer for dopamine, a gold or GCE working electrode, and a nanomaterial or nanocomposite to enhance sensitivity and conductivity 106‐115 . The role of aptamers is to selectively recruit dopamine to the electrode surface, while the signal was still from the redox chemistry of dopamine.…”

Section: Electochemical Biosensors Based On Oxidation Of Dopaminementioning

confidence: 99%

Biosensors and sensors for dopamine detection

Liu

2020

VIEW

176

122

View full text Add to dashboard Cite

Dopamine is a key catecholamine neurotransmitter and it has critical roles in the function of the human central nervous system. Abnormal release of dopamine is related to neurological diseases and depression. Therefore, it is necessary to monitor dopamine levels in vivo and in real time to understand its physiological roles. In this review, we discuss dopamine detection focusing on the molecular recognition methods including enzymes, antibodies, and aptamers, as well as new advances based on nanomaterials and molecularly imprinted polymers (MIPs). A large fraction of these sensors rely on electrochemical detection to fulfill the requirement of fast, in situ, and in vivo detection with a high spatial and temporal resolution. These methods need to overcome interferences from molecules with a similar redox potential. In addition, fluorescent and colorimetric sensors based on aptamers are also quite popular, and care needs to be taken to validate specific dopamine binding. Combining aptamers or MIPs with electrochemistry promises to achieve rapid detection and increased selectivity. In this article, we pay more attention to the molecular recognition mechanism and critically review the sensor designs. In the end, some future directions are discussed.

show abstract

Section: Electochemical Biosensors Based On Oxidation Of Dopaminementioning

confidence: 99%

Biosensors and sensors for dopamine detection

Liu

2020

VIEW

176

122

View full text Add to dashboard Cite

show abstract

“…The value of LOD for DA can be considered too high when compared to the value reported by Azadbakht et al. [ 147 ]…”

Section: Detection Of Nts Using Cnt‐based Sensorsmentioning

confidence: 79%

“…At this electrode, DA concentration showed a linear relationship with the current response and a LOD of 0.7 nM. This LOD is slightly lower than the value reported for another aptasensor by Azadbakht et al [147] In an attempt to fabricate an electrode based on an aniline derivative capable of solubility in organic medium and equally biocompatible, Sangamithirai et al designed a novel poly(o-anisidine)(POA)/CNTs modified GCE for the detection of DA. [153] This electrode tagged POA/CNTs/GCE was fabricated by dropping of POA/CNTs dispersion on bare GCE.…”

Section: Cnts Enhanced Electrochemical Da Detection (2015-2016)mentioning

confidence: 89%

“…[149] Using the very sensitive DPV, simultaneous determination of DA, UA, and Trp yielded LODs of 0.05, 0.5, and 1.0 µM, respectively. The value of LOD for DA can be considered too high when compared to the value reported by Azadbakht et al [147] Oh et al designed a GCE modified with charged MWCNTs for the determination of DA in the presence of AA and UA at a physiological level [150] in 2016. Charged MWCNTs obtained by immersing pristine MWC-NTs into a solution of citric acid (CA) or PEI to form a CA/MWCNTs or PEI/MWCNTs suspension was dispersed on GCE to fabricate a modified working electrode.…”

Section: Cnts Enhanced Electrochemical Da Detection (2015-2016)mentioning

confidence: 94%

“…Azadbakht et al fabricated an aptasensor based on the coupling of AuNPs-PEI-functionalized CNTs with 12 bases containing oligonucleotide (ssDNA1) and 58 bases containing DA aptamer (ssDNA2) in the presence of methylene blue (MB) as the electrochemical indicator. [147] This composite designated AuNPs-PEI-CNTs/aptamers/MB was immobilized on a gold (Au) electrode to obtain the modified Au electrode for DA detection. MB has a strong affinity for doublestranded DNA (dsDNA) and in the presence of DA, MB is released from the dsDNA and DA was measured in terms of MB concentration.…”

Section: Cnts Enhanced Electrochemical Da Detection (2015-2016)mentioning

confidence: 99%

See 2 more Smart Citations

Progress in electrochemical detection of neurotransmitters using carbon nanotubes/nanocomposite based materials: A chronological review

et al. 2020

View full text Add to dashboard Cite

Neurotransmitters (NTs) are chemical compounds that play an important physiological role in the functioning of central nervous, renal, hormonal, and cardiovascular systems. Their function is to regulate neural interactions by reducing the permeability of gap junctions between adjacent neurons of the same type. The abnormal level may lead to diseases, such as Parkinson's disease, Huntington's disease, Alzheimer's diseases, and other neurological diseases. The devastating health hazards associated with the abnormal presence of NTs in biological systems coupled with the demerits of most modern detection methods necessitates the continuous development of novel electrochemical sensors. Carbon nanotube (CNT)-based sensors, as a result of the large surface area, biocompatibility, and chemical stability supplied by CNTs, have proven to offer massive sensitivity and low limit of detection (LOD). Its significance in sensors applications toward the detection of different group of compounds cannot be overemphasized. There are several review articles on NTs and their determination using different chemically modified electrodes and sensor platform. However, this review highlights the significance of notable NTs and the progress made in the last decade in the design of CNT-based sensors for the detection of common NTs. Secondly, the This is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.

show abstract

Carbon Nanomaterials in Biological Studies and Biomedicine

Teradal

Jelinek

2017

Adv Healthcare Materials

178

View full text Add to dashboard Cite

The "carbon nano-world" has made over the past few decades huge contributions in diverse scientific disciplines and technological advances. While dramatic advances have been widely publicized in using carbon nanomaterials such as fullerenes, carbon nanotubes, and graphene in materials sciences, nano-electronics, and photonics, their contributions to biology and biomedicine have been noteworthy as well. This Review focuses on the use of carbon nanotubes (CNTs), graphene, and carbon quantum dots [encompassing graphene quantum dots (GQDs) and carbon dots (C-dots)] in biologically oriented materials and applications. Examples of these remarkable nanomaterials in bio-sensing, cell- and tissue-imaging, regenerative medicine, and other applications are presented and discussed, emphasizing the significance of their unique properties and their future potential.

show abstract

A label-free aptasensor based on polyethyleneimine wrapped carbon nanotubes in situ formed gold nanoparticles as signal probe for highly sensitive detection of dopamine

Cited by 43 publications

References 43 publications

Biosensors and sensors for dopamine detection

Biosensors and sensors for dopamine detection

Progress in electrochemical detection of neurotransmitters using carbon nanotubes/nanocomposite based materials: A chronological review

Carbon Nanomaterials in Biological Studies and Biomedicine

Contact Info

Product

Resources

About