Qi Zhao, Hui Shen, Kuan-Jui Su, Qing Tian, Lan-Juan Zhao, Chuan Qiu, Timothy J. Garrett, Jiawang Liu, David Kakhniashvili, Hong-Wen Deng
Abstract:Both loss of muscle mass and strength are important sarcopenia-related traits. In this study, we investigated both specific and shared serum metabolites associated with these two traits in 136 Caucasian women using a liquid chromatography-mass spectrometry method. A joint analysis of multivariate traits was used to examine the associations of individual metabolites with muscle mass measured by the body mass index-adjusted appendicular lean mass (ALM/BMI) and muscle strength measured by hand grip strength (HGS)…
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