volume 10, issue 10, P2624-2635 2018
DOI: 10.18632/aging.101574
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Qi Zhao, Hui Shen, Kuan-Jui Su, Qing Tian, Lan-Juan Zhao, Chuan Qiu, Timothy J. Garrett, Jiawang Liu, David Kakhniashvili, Hong-Wen Deng

Abstract: Both loss of muscle mass and strength are important sarcopenia-related traits. In this study, we investigated both specific and shared serum metabolites associated with these two traits in 136 Caucasian women using a liquid chromatography-mass spectrometry method. A joint analysis of multivariate traits was used to examine the associations of individual metabolites with muscle mass measured by the body mass index-adjusted appendicular lean mass (ALM/BMI) and muscle strength measured by hand grip strength (HGS)…

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