A Histologic Study of the Effects of Several Periodontal Dressings on Periosteal-covered and Denuded Bone

Effect of Periodontal Dressings on Human Gingival Fibroblasts In vitro

“…Also, the 1:16 dilution of Wondrpak was significantly differentfrom PPC (P < 0.05). 24 four types inhibited 3HTdR incorporation (Fig. 4) and the majority of cells had a round morphology ( Fig.…”

“…Phase contrast microscopy showed that the HGF did not become confluent during the course of the study in either the experimental or control groups. HGF exposed to either dressing extract or control solutions were assayed for 3HTdR incorporation following 24…”

“…Replicate HGF cultures grown in microtiter plates were exposed to stock, 1:4 and 1:16 dilutions of extracts made from each of the four periodontal dressings. The HGF cultures were pulse labelled with tritiated thymidine (3HTdR) after 24,48, and 72 hours. Incorporations of the labelled thymidine were measured using liquid scintillation counting and expressed as counts per minute.…”

Connective Tissue Reaction to Implants of Periodontal Packs

“…5,6,7,8 Since a delay in healing, when alveolar bone is exposed, might in part be due to the eugenol content of the dressing, non-eugenol packs have been developed and tested. 9,10 A paraffin pack has also been suggested. 11 A controversy has existed as to the superiority of a certain pack.…”

“…This study was designed to investigate the effects of varying the added ingredients in a basic zinc oxide-eugenol type of dressing as to their relative capacity to evoke an inflammatory response in the connective tissue. In view of the supposedly irritative effect of eugenol, 9,10,12 this investigation was extended to study the comparative effect of several eugenol and non-eugenol type of packs. Rat connective tissue was selected since previous studies had established the adequacy of the procedure for implantation of dental materials.…”