A histologic, histomorphometric, and radiographic comparison between two complexes of CenoBoen/CenoMembrane and Bio-Oss/Bio-Gide in lateral ridge augmentation: A clinical trial

Abstract

Background:Several grafting materials have been used for alveolar ridge augmentation. The literature lacks researches to compare CenoBone to other grafting materials. The aim of this study was to compare CenoBone/CenoMembrane complex to Bio-Oss/Bio-Gide complex in lateral alveolar bone augmentation in terms of radiographic, histologic, and histomorphometric parameters.Materials and Methods:In this randomized controlled trial, ten patients who needed lateral ridge augmentation were selected and augmentations were done using either of CenoBone/CenoMembrane or Bio-Oss/Bio-Gide complexes. In the re-entry surgery in 6 months following augmentation, core biopsies were taken and clinical, radiographic, histologic, and histomorphometric evaluations were performed.Results:No statistically significant difference was seen between groups except for the number of blood vessels and percentage of residual graft materials.Conclusion:CenoBone seems to present a comparable lateral ridge augmentation to Bio-Oss in.

A Histologic, Histomorphometric, and Immunohistochemical Evaluation of Anorganic Bovine Bone and Injectable Biphasic Calcium Phosphate in Humans: A Randomized Clinical Trial

“…According to the literature on human studies using this form of xenograft six months after augmentation, an older study by Zitzmann et al in 2001 [ 77 ] confirmed 36.7 ± 26.6% newly formed bone, 30.5 ± 4.6% residual BSB, and 37.6 ± 20.5% soft tissue structures, which is similar to the results obtained in this study. A more recent study by Amoian et al [ 78 ] can also be related to this control group in terms of newly formed bone, which was 38.66% in this study, although the sample consisted of only six patients. On the other hand, the study by Scarano et al [ 79 ], although performed on a much larger number of subjects, confirmed the regenerative effect of Bio-Oss ® in terms of newly formed bone with 39 ± 1.6%, 31 ± 1.4%, residual BSB, and 34 ± 1.6% soft tissue structures, which is the closest to the results obtained in this study six months after augmentation with the same BSB.…”

Potentials of pure xenograft materials in maxillary ridge augmentation: A case series

“…Autogenous and allogenic bone substitutes and even autogenous block grafts have been used for horizontal ridge augmentation in clinical studies ( Starch-Jensen et al, 2022 ). However, granular graft materials have been used for horizontal ridge augmentation in the majority of GBR-based procedures ( Amoian et al, 2016 ). Nonetheless, clinical information regarding the 1:1 ratio of autogenous bone/xenograft material or even autogenous bone/synthetic material is much more abundant than other graft materials ( Elamrousy et al, 2021 ).…”

Influence of melatonin associated with the Bio-Gide® membrane on osteoblast activity: an in vitro study

“…Bio-Gide® is a porcine resorbable membrane, comprised of a double layer of Type I and III collagen, indicated for tissue regeneration. It may act as a tissular barrier as it promotes the deposition of new bone with a stable absorption rate, without causing tissue inflammation 15 , 16 .…”

“…With the aim of enhancing GBR (Guided Bone Regeneration), different biomaterials associated with the use of membranes have been studied 13 , 14 , 16 . Thus, being a synthetic hormone that could potentially impact on bone formation, melatonin could be associated with membranes in regeneration processes.…”