A highly sensitive and selective fluorescent chemosensor for the sequential recognition of Zn2+ and S2− in living cells and aqueous media

A New Chromone‐based Sequential Functioning Colorimetric Chemosensor for Cu2+ and Cysteine in Near‐perfect Aqueous Media

“…However, these methods have problems of low sensitivity, high‐priced equipment, and complicated analysis [7–11] . Meanwhile, optical detection methods like colorimetry have the advantages of being simple, sensitive, and cheap through immediate color variations [10,12–19] . For those reasons, it is needed to develop colorimetry sensors to simply detect metals or amino acids [20–23] …”

“…[7][8][9][10][11] Meanwhile, optical detection methods like colorimetry have the advantages of being simple, sensitive, and cheap through immediate color variations. [10,[12][13][14][15][16][17][18][19] For those reasons, it is needed to develop colorimetry sensors to simply detect metals or amino acids. [20][21][22][23] Copper is essential for physiological body functions like mitochondrial electron transfer, neurotransmission process, melanin production, and bone formation.…”

Fluorescence ‘turn-on’ probe for nanomolar Zn(ii) detection in living cells and environmental samples

“…By contrast, simplicity and high sensitivity are the most attractive features of fluorescence-based methods that detect Zn 2+ in in vitro/in vivo settings. [25][26][27][28][29][30][31][32][33][34][35][36][37][38][39] However, among these methods, fluorescence-quenching-based probes are not suitable for analyzing intracellular analytes. [40][41][42][43] In this context, a fluorescence turn-on chemosensor with high sensitivity and specificity is crucial for detecting intracellular Zn 2+ .…”

Rhodamine‐based Colorimetric and Fluorescent Chemosensors for the Detection of Cu2+ Ions and its Application to Bioimaging

“…2 Several analytical techniques, such as anodic stripping voltammetry, 3 spectrophotometry, 4 X-ray fluorescence spectrometry, 5 neutron activation analysis, 6 inductively coupled plasma mass spectrometry (ICP-MS), 7 atomic fluorescence spectrometry, 8 and electrothermal atomic absorption spectrometry 9 are available for detection of heavy metal ions. [18][19][20][21][22][23][24][25] Varied fluorophores with different excitation and emission wavelengths have been employed for this purpose, such as xanthone (rhodamine and fluorescein), anthraquinone, quinolone, acridinone, coumarin, 1,8-naphthalimide, 4-amino-7-nitrobenzoxa-1,3-diazole (ANBD), and 4,4-difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY). Fluorescence chemosensors provide many advantages including operational ease, high selectivity, low cost, and real-time monitoring.…”

“…As such, there has been a significant amount of resources devoted to design and development of novel fluorescence chemosensors to detect presence of metal ions . When these chemosensors encounter a metal ion in solution (organic or aqueous solution), a change in their optical characteristic is observed, such as a change in wavelength, a change in emission intensity, or the appearance of a novel fluorescence band . Varied fluorophores with different excitation and emission wavelengths have been employed for this purpose, such as xanthone (rhodamine and fluorescein), anthraquinone, quinolone, acridinone, coumarin, 1,8‐naphthalimide, 4‐amino‐7‐nitrobenzoxa‐1,3‐diazole (ANBD), and 4,4‐difluoro‐4‐bora‐3a,4a‐diaza‐s‐indacene (BODIPY) …”