A highly selective electrochemical sensor for nifedipine based on layer‐by‐layer assembly films from polyaniline and multiwalled carbon nanotube

Wang, Qiguan; Zhao, Rongna; Wang, Sumin; Guo, Hao; Li, Jinhua; Zhou, Hongwei; Wang, Xinhai; Wu, Xinming; Wang, Yan; Chen, Weixing; Zhang, Wenzhi

doi:10.1002/app.43452

Cited by 12 publications

(5 citation statements)

References 42 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…PVA is also a biodegradable material that is safe for the human body (60,61). PVA has a lower Young's modulus (707.9 MPa) than silk (14 to 36 GPa), which helps the microneedle sensor achieve conformal contact with the skin, and it exhibits favorable optical properties such as high optical transparency and transmittance (60)(61)(62)(63)(64)(65)(66)(67)(68). The size of the device is about 7 mm by 7 mm, and the length of the microneedle can be customized according to the target race, location, and skin condition of the patient.…”

Section: Design Concept and Principle Of The Biodegradable Microneedl...mentioning

confidence: 99%

Fluorescent-based biodegradable microneedle sensor array for tether-free continuous glucose monitoring with smartphone application

et al. 2023

View full text Add to dashboard Cite

Continuous glucose monitoring (CGM) allows patients with diabetes to manage critical disease effectively and autonomously and prevent exacerbation. A painless, wireless, compact, and minimally invasive device that can provide CGM is essential for monitoring the health conditions of freely moving patients with diabetes. Here, we propose a glucose-responsive fluorescence-based highly sensitive biodegradable microneedle CGM system. These ultrathin and ultralight microneedle sensor arrays continuously and precisely monitored glucose concentration in the interstitial fluid with minimally invasive, pain-free, wound-free, and skin inflammation–free outcomes at various locations and thicknesses of the skin. Bioresorbability in the body without a need for device removal after use was a key characteristic of the microneedle glucose sensor. We demonstrated the potential long-term use of the bioresorbable device by applying the tether-free CGM system, thus confirming the successful detection of glucose levels based on changes in fluorescence intensity. In addition, this microneedle glucose sensor with a user-friendly designed home diagnosis system using mobile applications and portable accessories offers an advance in CGM and its applicability to other bioresorbable, wearable, and implantable monitoring device technology.

show abstract

Section: Design Concept and Principle Of The Biodegradable Microneedl...mentioning

confidence: 99%

Fluorescent-based biodegradable microneedle sensor array for tether-free continuous glucose monitoring with smartphone application

et al. 2023

View full text Add to dashboard Cite

show abstract

“…The surface of the electrode can be modified by simply coating these nanomaterials that can be attached to the electrode surface by non-covalent forces or covalent modification [ 62 ]. Moreover, the surface coating of materials can be performed by different strategies, such as layer-by-layer assembly [ 63 ], electrophoretic deposition [ 64 , 65 ], spin coating [ 66 ], dip coating [ 67 ], or electrospinning [ 68 ]. When the modified surface forms a thin film, it provides a higher conductivity and stability that leads to increased sensitivity for the lifetime of the electrochemical sensor.…”

Section: Electrochemical Sensorsmentioning

confidence: 99%

Recent Advances of Enzyme-Free Electrochemical Sensors for Flexible Electronics in the Detection of Organophosphorus Compounds: A Review

Pathiraja

Bonner

Obare

2023

Sensors

View full text Add to dashboard Cite

Emerging materials integrated into high performance flexible electronics to detect environmental contaminants have received extensive attention worldwide. The accurate detection of widespread organophosphorus (OP) compounds in the environment is crucial due to their high toxicity even at low concentrations, which leads to acute health concerns. Therefore, developing rapid, highly sensitive, reliable, and facile analytical sensing techniques is necessary to monitor environmental, ecological, and food safety risks. Although enzyme-based sensors have better sensitivity, their practical usage is hindered due to their low specificity and stability. Therefore, among various detection methods of OP compounds, this review article focuses on the progress made in the development of enzyme-free electrochemical sensors as an effective nostrum. Further, the novel materials used in these sensors and their properties, synthesis methodologies, sensing strategies, analytical methods, detection limits, and stability are discussed. Finally, this article summarizes potential avenues for future prospective electrochemical sensors and the current challenges of enhancing the performance, stability, and shelf life.

show abstract

“…The fabrication of PANi nanoparticles-carboxylic acid-functionalized multiwalled carbon nanotubes (MWCNTs-COOH) film through the LBL self-assembly method for nifedipine (NIF) sensing has also been recently reported. The obtained LBL films exhibited uniform distribution of PANi-MWCNTs-COOH nanocomposites, which led to electronic communications of active materials and provided high facility, sensitivity and selectivity for detection of biomaterials [ 35 ].…”

Section: Introductionmentioning

confidence: 99%

Electrochemical Dopamine Biosensor Based on Poly(3-aminobenzylamine) Layer-by-Layer Self-Assembled Multilayer Thin Film

2021

View full text Add to dashboard Cite

Dopamine (DA) is an important neurotransmitter which indicates the risk of several neurological diseases. The selective determination with low detection limit is necessary for early diagnosis and prevention of neurological diseases associated with abnormal concentration of DA. The purpose of this study is to fabricate a poly(3-aminobenzylamine)/poly(sodium 4-styrenesulfonate) (PABA/PSS) multilayer thin film for use as an electrochemical DA biosensor. The PABA was firstly synthesized using a chemical oxidation method of 3-aminobenzylamine (ABA) monomer with ammonium persulfate (APS) as an oxidant. For electrochemical biosensor, the PABA/PSS thin film was fabricated on fluorine doped tin oxide (FTO)-coated glass substrate using the layer-by-layer (LBL) self-assembly method. The optimized number of bilayers was achieved using SEM and cyclic voltammetry (CV) results. The electroactivity of the optimized LBL thin film toward detection of DA in neutral solution was studied by CV and amperometry. The PABA/PSS thin film showed good sensitivity for DA sensing with sensitivity of 6.922 nA.cm−2.µM−1 and linear range of 0.1–1.0 µM (R2 = 0.9934), with low detection limit of 0.0628 µM, long-term stability and good reproducibility. In addition, the selectivity of the PABA/PSS thin film for detection of DA under the common interferences (i.e., ascorbic acid, uric acid and glucose) was also presented. The prepared PABA/PSS thin film showed the powerful efficiency for future use as DA biosensor in real sample analysis.

show abstract

A highly selective electrochemical sensor for nifedipine based on layer‐by‐layer assembly films from polyaniline and multiwalled carbon nanotube

Cited by 12 publications

References 42 publications

Fluorescent-based biodegradable microneedle sensor array for tether-free continuous glucose monitoring with smartphone application

Fluorescent-based biodegradable microneedle sensor array for tether-free continuous glucose monitoring with smartphone application

Recent Advances of Enzyme-Free Electrochemical Sensors for Flexible Electronics in the Detection of Organophosphorus Compounds: A Review

Electrochemical Dopamine Biosensor Based on Poly(3-aminobenzylamine) Layer-by-Layer Self-Assembled Multilayer Thin Film

Contact Info

Product

Resources

About