2004
DOI: 10.1002/elps.200305897
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A high‐performance multilane microdevice system designed for the DNA forensics laboratory

Abstract: We report preliminary testing of "GeneTrack", an instrument designed for the specific application of multiplexed short tandem repeat (STR) DNA analysis. The system supports a glass microdevice with 16 lanes of 20 cm effective length and double-T cross injectors. A high-speed galvanometer-scanned four-color detector was specially designed to accommodate the high elution rates on the microdevice. All aspects of the system were carefully matched to practical crime lab requirements for rapid reproducible analysis … Show more

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Cited by 61 publications
(48 citation statements)
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“…More recently, a system supporting a glass chip with 16 lanes of 20 cm effective length and double-T cross injector was presented by Goedecke et al [103]. An absolute three-sigma peak accuracy of 0.4-0.9 bp was reported for the CODIS 13-locus multiplex, utilizing a single channel per sample.…”
Section: Forensic Dna and Rna Analysismentioning
confidence: 99%
“…More recently, a system supporting a glass chip with 16 lanes of 20 cm effective length and double-T cross injector was presented by Goedecke et al [103]. An absolute three-sigma peak accuracy of 0.4-0.9 bp was reported for the CODIS 13-locus multiplex, utilizing a single channel per sample.…”
Section: Forensic Dna and Rna Analysismentioning
confidence: 99%
“…Several DNA approaches has been performed on chip such as mutation analysis, SNPs analysis, forensic human identification, and genotyping, [55][56][57][58][59][60][61][62] therefore a sensitive, efficient and low viscous separation media has become increasingly important for DNA separation on chip. Below several low viscous separation media has been introduced for analysis on chip.…”
Section: Low Viscous Separation Medias For Dna Separationmentioning
confidence: 99%
“…[11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27] Several types of chips has been introduced for the postgenomic researches such as DNA/RNA chips [28][29][30][31] and the serial analysis of gene expression. [32][33][34][35] The viscosity of the separation media is one important factor for chip separation since the bounded microfluidic devices can not withstand high loading pressure.…”
Section: Introductionmentioning
confidence: 99%
“…In the future, additional loci are likely to be added to routine forensic analysis. Forensic DNA fingerprinting utilizes a miniature system of electrophoretic columns to analyze the length of each of the 13 STR loci (5).…”
mentioning
confidence: 99%