A Hairless Mutation in the Rat

Hereditary defects and conservation genetic management of captive populations

“…Inherited disorders have been documented and studied for several decades, particularly in humans and domestic animals [Carris, 1932;Wilder et al, 1932;Gregory et al, 1942;Petersen et al, 1944;Gregory and Carroll, 1956;Stevenson and Davison, 1970 and references therein]. Establishing the etiology of various diseases, including the mode of inheritance in cases of hereditary defects is, of course, a primary concern within the fields of human and veterinary medicine.…”

The effect of vitamin A in hyperkeratotic mouse mutants

“…The most striking are those which result in hypotrichosis of varyinG degrees ranein-: from slif)lt thinninp of the pelage in sorne mutants to virtually complete hairlessness in others ( Anon. ,1917;Brooke ,1926;Castle ,1933;Castle ~ ,al, 1955;Carter and Phillips,l950;Crew and tiirskaia,l931-32;Dickie,l955;Dickie and Woolley,l950;Falconer et al,l950;Falconer and Snell,l952;Garber,l952;Green,l954;Howard,l940;Hutt and Saunders,l953;Letard, 1938;Loeffler,l934;Lyon,l956;Lebedevsky and Dauvert,l927;Roberts and Carroll,l936;Sunmer,l924;Wilder~ ~,1932). r.~tations which involve faulty development of epidermal appendages are also knovm in birds (Abbott and Asmundson,l957;Danforth,l928;Hutt and Sturkie,l938;Sturkie,l942), and cases resenbling hypotrichotic mutations in animals have been described in ~an (Albrechtsen and Svendsen,l956; Damste and Prakken,l954; Kylin and Dicker,l939).…”