A Haematological Study of 500 Elderly Females

Griffiths, H. J. L.; Nicholson, William J.; O’Gorman, Peter

doi:10.1159/000245258

Cited by 6 publications

(8 citation statements)

References 1 publication

(1 reference statement)

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“…Lloyd (16) reported a 20 percent incidence of anemia among 100 patients admitted to the Geriatric Service of the Glasgow Royal Infirmary. Evans et al (17) and Griffiths et al (18), however, reported a considerably lower incidence of anemia. Evans et al reviewed 2700 admissions to the geriatric wards of St. David's Hospital, Cardiff, and found that only 6.4 percent of all patients were anemic.…”

Section: Discussionmentioning

confidence: 93%

Anemia in Institutionalized Elderly Patients†

Kalchthaler

Tan

1980

J American Geriatrics Society

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In a one-year period (1976--1977), 161 residents of a long-term facility were evaluated. There were 44 men and 117 women. According to criteria established by the World Health Organization, 64 residents (40 percent) were anemic. The incidence was greater for women than for men. The peak incidence occurred in the 71--80 age group for women, and in the 90+ age group for men. Iron deficiency secondary to surgical procedures, gastrointestinal bleeding or anticoagulant therapy was the most common cause of correctable anemia. Of the 64 anemic patients, 42 percent responded to therapy. Anemia among the elderly in institutions is often reversible, unlike the anemia of chronic disease. Evaluation should include a careful history and physical examination plus readily available laboratory findings. Invasive procedures are rarely indicated.

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Section: Discussionmentioning

confidence: 93%

Anemia in Institutionalized Elderly Patients†

Kalchthaler

Tan

1980

J American Geriatrics Society

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“…Thus, it would be hazardous to decide on a “geriatric” normal range that would exclude such patients from further evaluation (1–5). Previous studies have pointed out the high frequency with which treatable forms of anemia, particularly iron‐deficiency anemia, are found in the elderly (6, 7).…”

Section: Discussionmentioning

confidence: 99%

“…Several recent studies have indicated that there is a normal decline in the erythrocyte count, hemoglobin concentration and hematocrit value with aging (1-5). Nevertheless, other workers have concluded that there is no change in these measurements apart from pathologic processes (6)(7)(8). If there is a decline in these parameters with aging, one might assign a new normal range for geriatric patients.…”

mentioning

confidence: 98%

Erythrocyte Parameters in the Elderly: An Argument Against New Geriatric Normal Values*

Htoo

Kofkoff

Freedman

1979

J American Geriatrics Society

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Erythrocyte parameters in 292 unselected geriatric patients were studied retrospectively. Statistically significant mean decreases compared to the laboratories' normal mean values were found in the red blood cell count (RBC), hemoglobin level, hematocrit, and mean corpuscular hemoglobin concentration; there also was a slight increase in mean corpuscular volume and mean corpuscular hemoglobin. However, when 17 patients with a hemoglobin level less than 10 gm/dl or a hematocrit reading less than 35 percent were excluded, all of the mean values for erythrocyte parameters fell within the normal range. In 71 percent of these 17 patients the etiology of the anemia was documented. Although one cannot definitely exclude a slight change in erythrocyte parameters with aging, it is concluded that the establishment of so-called new geriatric norms is premature, as the population studied included patients with various diseases. Good medical practice dictates continued evaluation and monitoring of patients in whom erythrocyte values are outside the established normal ranges.

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“…In contrast to the elderly population, [1][2][3][4] the prevalence of anemia in the palliative care population has not been previously described.…”

Section: Introductionmentioning

confidence: 99%

“…The prevalence of anemia in groups of elderly in hospitals, rest homes, or the community has been found to range from 8% to 26%. [1][2][3][4] General population-based studies of anemia have reported prevalence rates of 9% to 44%, with the highest prevalence in men 85 years or more. 8,9 Recently, prevalence rates of 41% (preradiation) and 54% (post-radiation) have been found in cancer patients undergoing radiation.…”

Section: Introductionmentioning

confidence: 99%

Anemia at the end of life: prevalence, significance, and causes in patients receiving palliative care

Dunn¹,

Carter²,

Carter³

2003

Journal of Pain and Symptom Management

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While data exist on the prevalence and causes of anemia in defined groups of the elderly, information on palliative care patients is limited. Compared to actively treated oncology patients, for whom anemia treatment has demonstrated improved quality of life and symptom alleviation, studies of treatment outcomes in palliative care patients are limited. Knowledge of the extent and causes of anemia in palliative care patients is needed, as correction of anemia in these patients could potentially improve their physical, emotional, and cognitive functioning. In the present study, clinical data and blood test results of 105 patients meeting specific eligibility criteria were examined to estimate the prevalence of anemia and investigate its causes. Ninety-five (90.5%) patients had advanced cancer. Based on World Health Organization criteria, anemia was found in 77% of men (Hb <130 g/l) and 68.2% of women (Hb <120 g/l). The diagnosis was anemia of chronic disease in 76.7% of women and 46.8% of men. Patients with prostate cancer had a significantly lower mean Hb level (P=0.007) and more evidence of bone metastases (P=0.0007) than those with other cancers. Neutrophil hypersegmentation, suggesting occult folate deficiency, was present in 28.6% of patients, being more common in those with major weight loss (58.3%) than those with moderate (37%) or mild/no weight loss (26%) (P=0.019). The findings suggest that anemia is highly prevalent in the palliative care setting. Although anemia of chronic disease is most common, occult folate deficiency may be more prevalent than previously suspected. The findings suggest that a low serum folate level is an insensitive marker of occult folate deficiency. A randomized controlled trial of folic acid treatment is proposed.

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A Haematological Study of 500 Elderly Females

Cited by 6 publications

References 1 publication

Anemia in Institutionalized Elderly Patients†

Anemia in Institutionalized Elderly Patients†

Erythrocyte Parameters in the Elderly: An Argument Against New Geriatric Normal Values*

Anemia at the end of life: prevalence, significance, and causes in patients receiving palliative care

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