A green protocol for peptide bond formation in WEB

Konwar, Manashjyoti; Ali, Abdul Aziz; Sarma, Diganta

doi:10.1016/j.tetlet.2016.04.041

Cited by 51 publications

(24 citation statements)

References 28 publications

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“…Very few works using agro‐waste surrogates have been reported . But, the scope and generality in regard to accessibility and abundance were quite periodic.…”

Section: Figurementioning

confidence: 99%

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Extraction of Base from Eichhornia crassipes and Its Implication in Palladium‐Catalyzed Suzuki Cross‐Coupling Reaction

et al. 2017

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The utilization of a sustainable and eco‐friendly alternative medium derived from water borne species Eichhornia crassipes (Common name: Water Hyacinth) for the Suzuki cross‐coupling reaction at room temperature was reported. The system provides an in situ basic condition via metal extraction from ash water extract of Eichhornia crassipes, which delivers a dual performance in the catalytic application. The distribution of metal contents in the ash was characterized by EDX (Energy‐dispersive X‐ray spectroscopy) analysis. The basicity of the medium may possibly be due to the formation of corresponding metal oxides or hydroxides in its water extract. The application of this ash water extract results in an effective cross‐coupling in palladium catalyzed Suzuki reaction without any external promoter or ligand. The central attraction of our reaction system is the fruitful utilization of highly abundant unwanted weeds instead of destruction of ecologically important plants or plant parts. The present system highlights an excellent green pathway that fits the global urge of sustainable development and will prevail wide application in variable synthetic studies.

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“…Very few works using agro‐waste surrogates have been reported . But, the scope and generality in regard to accessibility and abundance were quite periodic.…”

Section: Figurementioning

confidence: 99%

“…[41] Very few works using agro-waste surrogates have been reported. [42][43][44] But, the scope and generality in regard to accessibility and abundance were quite periodic. Thus, this aqueous extract in comparison to the mentioned literature well serves the world wide accessibility and terms of ecological footprints.…”

mentioning

confidence: 99%

Extraction of Base from Eichhornia crassipes and Its Implication in Palladium‐Catalyzed Suzuki Cross‐Coupling Reaction

et al. 2017

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“…Various Pd‐catalyzed reactions viz. Suzuki‐Miyaura and Sonogashira coupling, popular name reactions (for example Dakin and Henry reaction) and other organic synthesis such as peptide synthesis, azidation of aromatics and synthesis of 3‐carboxycoumarins have been successfully performed in this green reaction medium. Although WEB can be used alone, in some cases it has been mixed with organic solvents like ethanol and iso ‐propanol to increase the miscibility of reagents and starting materials so that the reactions furnish higher yields of the products .…”

Section: Introductionmentioning

confidence: 99%

A Green Protocol for the Synthesis of α‐Diazo‐β‐hydroxyesters and One‐Pot Conversion to β‐Keto‐Esters and Imidazo[1,2‐a]pyridine‐3‐carboxylates

et al. 2019

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A new solvent cum reagent system comprising of water extract of banana ash and dimethylsulfoxide (WEB‐DMSO) has been engaged for the first time to promote the aldol type condensation reaction of aldehydes with ethyl diazoacetate. The condensation reaction has smoothly undergone producing a range of α‐diazo‐β‐hydroxy esters in good to excellent yields. The solvent system has been reused up to five times without loss of its catalytic activity. Further, two one‐pot sequential reactions have been developed in the same reaction medium. First, the methodology has been extended to synthesize β‐keto esters through Pd catalyzed 1,2‐hydrogen migration. Secondly, β‐keto esters have been converted to imidazo[1,2‐a]pyridine‐3‐carboxylates by using N‐bromosuccinimide and 2‐aminopyridines in a one‐pot fashion.

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“…Therefore in the recent year's use of agro-waste stuff ash extract as a chemical surrogates becomes one of the most exciting discoveries of organic chemists [2]. Many authors reported a novel route for the Suzuki-Miyaura cross-coupling reactions using water extract of banana peel ash (WEB) as solvent system as well as in situ base for the reaction [3][4][5]. It is also well documented that burnt ash contains K, Na, CO 3 2− and Cl − as a major constituents along with a trace elements like Ca, Mg and Cu [6].…”

Section: Introductionmentioning

confidence: 99%

“…The application of microwave accelerated has been employed in various useful transformations involving condition, oxidation [40][41][42][43], reduction [44], protection-deprotection [45][46][47][48][49], rearrangement reactions synthesis of different heterocyclic scaffolds [50]. As part of our research interested on green method synthesis of biologically active heterocyclic scaffolds, we present one pot product formation of 2-amino-4H-chromene in water extract of banana peel ash [3,4]. The synthesis is influenced in the presence of microwave accelerated and grindstone method.…”

Section: Introductionmentioning

confidence: 99%

A Green Method Synthesis and Antimicrobial Activity of 2-Amino-4H-Chromene Derivatives

Kamanna¹,

Khatavi²

2018

Asian J. Chem.

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Agro-waste stuff ash extracted solution have been emerging in recent practicing green reaction catalysis in organic synthesis. The derived media have been demonstrated in reactions like Sonogashira, Dakin, Henry, Suzuki-Miyaura, amide bond formation. Traditionally, these reactions were performed in organic solvents and used expensive catalysts with elevated temperature. These catalytic media showed distinct properties during reaction course such as, in situ base, homogeneous catalysts and reducing agent. The present work reviewed green protocol synthesis of 2-amino-4H-chromene derivatives employing reaction of substituted benzaldehyde, malononitrile and α/βnaphthol or resorcinol; three component reaction catalyzed in the presence of water extract of banana peel ash (WEB) extraction under microwave and grindstone methods is described. The reaction found eco-friendly, simple reaction condition with easy separation of final product in pure form. The final product was characterized for its homogeneity using spectroscopic techniques. Some of the selected chromene derivatives (3b, 3d, 3g) prepared in this method is tested for its in vitro antimicrobial studies. The bioassay revealed that products 3b and 3d showed positive response and comparable antimicrobial activity with the reference compounds.

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A green protocol for peptide bond formation in WEB

Cited by 51 publications

References 28 publications

Extraction of Base from Eichhornia crassipes and Its Implication in Palladium‐Catalyzed Suzuki Cross‐Coupling Reaction

Extraction of Base from Eichhornia crassipes and Its Implication in Palladium‐Catalyzed Suzuki Cross‐Coupling Reaction

A Green Protocol for the Synthesis of α‐Diazo‐β‐hydroxyesters and One‐Pot Conversion to β‐Keto‐Esters and Imidazo[1,2‐a]pyridine‐3‐carboxylates

A Green Method Synthesis and Antimicrobial Activity of 2-Amino-4H-Chromene Derivatives

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