2015
DOI: 10.1016/j.bdq.2015.04.001
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A glance at the applications of Singular Spectrum Analysis in gene expression data

Abstract: In recent years Singular Spectrum Analysis (SSA) has been used to solve many biomedical issues and is currently accepted as a potential technique in quantitative genetics studies. Presented in this article is a review of recent published genetics studies which have taken advantage of SSA. Since Singular Value Decomposition (SVD) is an important stage of this technique which can also be used as an independent analytical method in gene expression data, we also briefly touch upon some areas of the application of … Show more

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Cited by 13 publications
(8 citation statements)
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“…Since numerous specific component grouping methods were separately proposed for SSA to reconstruct sinusoids [23], [24], trends [25] or noise [6], [9], all of them suffer of a lack of flexibility and require to be manually adapted to the analyzed signal to provide meaningful results. More recently, efforts aim at making the SSA fully automatic [26]- [28] and adaptive for any component type.…”
Section: B Automatic Grouping Of Componentsmentioning
confidence: 99%
See 1 more Smart Citation
“…Since numerous specific component grouping methods were separately proposed for SSA to reconstruct sinusoids [23], [24], trends [25] or noise [6], [9], all of them suffer of a lack of flexibility and require to be manually adapted to the analyzed signal to provide meaningful results. More recently, efforts aim at making the SSA fully automatic [26]- [28] and adaptive for any component type.…”
Section: B Automatic Grouping Of Componentsmentioning
confidence: 99%
“…with < x, y > = x T y and ||x|| = √ < x, x > (6) but can also be replaced by the weighted correlation (wcorrelation) as defined in [33]. This algorithm provides a binary tree that can be called a dendrogram, which shows at each iteration the result of the merging process.…”
Section: B Automatic Grouping Of Componentsmentioning
confidence: 99%
“…SSA, as a time series analysis tool used to decompose an original time sequence into interpretable components, has been applied in many fields, including biology, physics, climatology, and economics [35][36][37][38]. The decomposition process can be divided into four steps:…”
Section: Singular Spectrum Analysis (Ssa)mentioning
confidence: 99%
“…In recent years, singular spectrum analysis (SSA), a relatively novel and powerful nonparametric technique in time series analysis, has been developed and applied to many practical problems across different fields. [1][2][3][4][5][6][7][8][9][10][11][12][13][14][15] The SSA algorithm incorporates elements of classical time series analysis, multivariate statistics, multivariate geometry, dynamical systems and signal processing, 16,17 and can be used for: smoothing, trend extraction, extraction of periodicities, forecasting, filling in missing values, estimating signal parameters, detection of change points, and finding causality between series. Being a nonparametric approach, although some probabilistic and statistical concepts are employed in the SSA algorithm, no statistical assumptions such as stationarity of the series or normality of the residuals are required.…”
Section: Introductionmentioning
confidence: 99%