A giant phyllodes tumor causing ulceration and severe breast disfigurement: case report and review of giant phyllodes

Sbeih, Mohammed A.; Engdahl, Ryan; Landa, Marina; Ojutiku, Oreoluwa; Morrison, Norman; DePaz, H.A

doi:10.1093/jscr/rjv162

Cited by 11 publications

(10 citation statements)

References 10 publications

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“…Adjuvant treatment of giant phyllodes tumour given varies in available literature. For borderline or benign phyllodes, no adjuvant treatment was given [10,11]. In the case described by Islam et al, low-grade malignant phyllodes was not given any adjuvant treatment [7].…”

Section: Discussionmentioning

confidence: 99%

A Huge Benign Phyllodes Tumour of the Breast: a Rare Entity

Paryani

2019

Indian J Surg Oncol

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Section: Discussionmentioning

confidence: 99%

A Huge Benign Phyllodes Tumour of the Breast: a Rare Entity

Paryani

2019

Indian J Surg Oncol

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“…The pathogenesis of phyllodes tumour is that it arises from outside of the ducts and lobules and occurs mostly in the breast's connective tissue unlike breast carcinoma otherwise called stroma which surround the ducts and lobules along with vessels and lymphatics [8,11] Pătraşcu et al [1] in 2009 have suggested that phyllodes tumour is unilateral, more common over the right breast and <1% of the tumours are bilateral [1]. These tumours are typically painless rapidly growing tumours [12]. Diagnosis by FNAC can be difficult as both phyllodestumours and fibro adenomas belong to a spectrum of fibro epithelial lesions.…”

Section: Discussionmentioning

confidence: 99%

Malignant Phyllodes Tumour in a 42 Year Old Mother

Vasudevan¹

2017

IJSST

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One among every nine women is diagnosed with breast cancer and it is the second main cause of death by cancer in women. Ductal carcinoma is the most common histopathological type of breast cancer. Phyllodes tumours are rare fibro epithelial lesions and constitute to about 0.3-0.9% among female breast tumours and occur in the 4th decade of life. Here we present a 42 year old mother who came to our ER with complaints of right sided breast lump and mastalgia for 6 months. She was diagnosed to have angiosarcoma through FNAC. She was admitted in our hospital for further evaluation and management. The tumour was staged as T3 N1 M0. The patient was taken up for modified radical mastectomy of the right breast with latissimusdorsi flap reconstruction. Histopathology reports suggested poorly differentiated sarcoma in a background of malignant phyllodes tumour. 3 out of 13 nodes were positive for nodal involvement.

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“…The main options of local PT treatment are breast preserving operation with excision of normal breast tissue around the tumor (to obtain of at least a 1 cm margin [1975][1976][1977][1978][1979][1980][1981][1982][1983][1984][1985][1986] the bloodstream, the lymph node metastases rates are very low (<5%). Thus, axillary dissection is unnecessary during the initial surgical intervention [10,11,12]. Radiotherapy is recommended for individuals with a high local recurrence risk.…”

Section: Discussionmentioning

confidence: 99%

“…Chemotherapy is used to treat patients with a high systemic metastatic risk. The real role of adjuvant irradiation and chemotherapy is undefined and should be tested in prospective, randomized trials [10,11,12,15,16].…”

Section: Discussionmentioning

confidence: 99%

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Gigantinis piktybinis filoidinis krūties navikas: klinikinio atvejo aprašymas ir literatūros apžvalga

Ostapenko¹,

Ostapenko²,

Dasevičius³

et al. 2016

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IntroductionPhyllodes tumors of the breast are rare and account for less than 1% of breast tumors. They occur over a wide age range with a median age of 45 years. Malignant transformation of a phyllodes tumor is a rare form of breast cancer accounting for just 0.5% of all breast cancers. A simple mastectomy is performed for giant phyllodes tumors (>10 cm), those that are multifocal, in cases of malignant phyllodes tumors, in cases of recurrence or in phyllodes of 'borderline' histology Case report We report a rare case of a rapidly growing malignant giant phyllodes tumor of the young, 26 year-old white woman, who underwent successful combined treatment nipple-sparing mastectomy and irradiation in National Cancer Institute, Vilnius, Lithuania Conclusions Multidisciplinary approach and modern imaging studies allows us to diagnose and successfully treat this rare pathological state. Scientific trials to delineate proper indications for combined treatment malignant phyllodes tumor of the young patients are needed. Key words: malignant breast phyllodes tumors, combined treatment, nipple-sparing mastectomy Įvadas Krūties filoidiniai navikai yra reta patologinė būklė, sudaranti mažiau negu 1 % krūties navikų. Filoidiniai navikai pasitaiko įvairaus amžiaus moterims, amžiaus vidurkis yra 45 metai. Filoidinių navikų malignizacija pasitaiko retai ir sudaro 0,5 % visų krūties navikų. Paprastoji mastektomija rekomenduojama esant gigantiniams filoidiniams navikams (>10 cm), navikų daugiažidiniškumui, ligos atsinaujinimui ir histologiškai patvirtintam paribiniam filoidiniam navikui. V . O s t a p e n k o , A . O s t a p e n k o , D . D a s e v i č i u s , E . O s t a p e n k o Klinikinis atvejisAprašome retą piktybinio filoidinio naviko atvejį 26 metų moteriai, kuri sėkmingai gydyta Nacionaliniame vėžio institute Vilniuje, derinant spenelį tausojančią mastektomiją ir aktinoterapiją. Išvados Daugiadalykis atvejo aptarimas ir modernūs tyrimo metodai leidžia diagnozuoti ir sėkmingai gydyti šią retą patologiją. Reikalingi tolesni piktybiniais filoidiniais navikais sergančių jaunų pacienčių moksliniai tyrimai, naujos sudėtinio gydymo indikacijos ir gydymo standartai.Reikšminiai žodžiai: piktybiniai filoidiniai krūties navikai, sudėtinis gydymas, spenelį tausojanti mastektomija

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A giant phyllodes tumor causing ulceration and severe breast disfigurement: case report and review of giant phyllodes

Cited by 11 publications

References 10 publications

A Huge Benign Phyllodes Tumour of the Breast: a Rare Entity

A Huge Benign Phyllodes Tumour of the Breast: a Rare Entity

Malignant Phyllodes Tumour in a 42 Year Old Mother

Gigantinis piktybinis filoidinis krūties navikas: klinikinio atvejo aprašymas ir literatūros apžvalga

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