A FRET-based probe for detection of the endogenous SO2 in cells

Luminescent Imidazo[1,5‐a]pyridine Scaffold: Synthetic Heterocyclization Strategies‐Overview and Promising Applications

“…The reported impy compounds display mono-electronic oxidation (generally reversible), characterized by half-wave potential E 1/2 of about 400 mV (versus ferrocene/ferrocenium reference, Fc/Fc + ), as previously reported for impy derivatives and corresponding complexes. [4,26,28,67,111] Many works have been reported concerning the application of different impy products as molecular sensors, [121] for example for the quantification of hydrogen sulphide [122,109,123] and hydrogen polysulphides, [124] sulphur dioxide, [125] hypochlorous acid, [126][127][128] and metal ions such as Cu 2 + , [129] Cd 2 + and Zn 2 + , [130] Hg 2 + . [11] Moreover, impy products have been successfully employed as ratiometric pH-Sensors based on a dual emission pathway [29,30] or as fluorescent pH probes in living cells.…”

A novel fluorescent probe based on triphenylamine for detecting sulfur dioxide derivatives

“…According to previous reports, GSH and Na 2 S 2 O 3 can react to produce sulfite under physiological conditions. 57 We select GSH and Na…”

A ratiometric fluorescent probe for detection of exogenous mitochondrial SO2 based on a FRET mechanism

“…Compound 4 were synthesized according to the literature. 33 Compound 4 (253 mg, 1 mmol) was added to 30 mL dichloromethane and then DMAP (183 mg, 1.5 mmol) and EDC (288 mg, 1.5 mmol) were added. Aer stirring at room temperature for half an hour, compound 3 (488 mg, 1 mmol) was added and stirred for 12 hours at room temperature.…”

“…[30][31][32] To date, some well-behaved ratiometric uorescent probes for SO 2 derivatives have been developed. [33][34][35][36] However, there is great room for improvement since these probes are still subject to some drawbacks such as unsatisfactory detection limits, long response time, and poor selectivity over H 2 S. Recently, we successfully synthesized the imidazole [1,5-a]pyridine via a tandem reaction. [37][38][39] Some uorescent probes based on this new uorophore for Cu 2+ , and Hg 2+ have been constructed subsequently.…”