A flow injection method for the analysis of tetracycline antibiotics in pharmaceutical formulations using electrochemical detection at anodized boron-doped diamond thin film electrode

Differential pulse voltammetric determination of dopamine with the coexistence of ascorbic acid on boron-doped diamond surface

“…These properties make the BDD electrode a promising material for electroanalytical applications. It was reported that anodic pretreatment of the BDD electrode makes it possible to determine NADH and other bio-molecules separately [22,23].…”

Analysis of Tetracycline Antibiotics Using HPLC with Pulsed Amperometric Detection

“…[29][30][31] Recently, it was found that BDD electrodes pretreated by electrochemical oxidation exhibit well-defined irreversible cyclic voltammograms for the oxidation of tetracycline antibiotics with the highest current signals compared to the asdeposited BDD and glassy carbon electrodes. 32 These anodized BDD electrodes retain the excellent properties of the asdeposited diamond electrode.…”

“…[30][31][32][33] To obtain higher sensitivity, the anodized BDD has been used as the working electrode for pulsed amperometric detection coupled with HPLC. Finally, we applied the proposed method to determine tetracycline antibiotics in shrimps.…”

Flow-injection spectrophotometric determination of tetracycline and doxycycline in pharmaceutical formulations using chloramine-T as oxidizing agent

“…Since the conventional spectrophotometric methods for tetracyclines determinations are tedious and time consuming, flow injection analysis (FIA) methods with chemiluminescence, [24][25][26][27] amperometric [28][29][30] and spectrophotometric [31][32][33][34] detection have been employed instead. The automated flow injection analysis systems with spectrophotometric detection present as main disadvantages the relatively high cost of reagents, 32 very low sampling rate 34 and low selectivity.…”

“…The automated flow injection analysis systems with spectrophotometric detection present as main disadvantages the relatively high cost of reagents, 32 very low sampling rate 34 and low selectivity. 31,33 The methodologies that employ flow systems with amperometric [28][29][30] and chemiluminescence detection, [24][25][26][27] despite their high analytical sensitivity, present the disadvantages of relative high cost [28][29][30] as well as the use of oxidizing reagents which are expensive 25 or highly toxic. 26,27 Visible absorption spectrophotometry was applied in pioneering works on flow injection analysis.…”