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Abstract:Monitoring the vital signs and physiological responses of the human body in daily activities is particularly useful for the early diagnosis and prevention of cardiovascular diseases. Here, we proposed a wireless and flexible biosensor patch for continuous and longitudinal monitoring of different physiological signals, including body temperature, blood pressure (BP), and electrocardiography. Moreover, these modalities for tracking body movement and GPS locations for emergency rescue have been included in biosen… Show more
“…Overall analysis in this comprehensive review article our main intension to focus on the Nanoscience and Nanotechnology enabled integrated analysis of various nanostructure utilizes smart biosensor implementations in diagnostics field of cancer treatment via Internet of healthcare things and mobile things (IoHT and IoMT) [17] of details machine learning operating system of biosensor activities are depicted in Fig. 4 [18] . In addition to this, finally a mobile friendly user interface (UI) application was developed for medical inspections and healthcare perception.…”
Section: Role Of Electrochemical Biosensors In Sars-cov-2/covid-19 Co...mentioning
“…Overall analysis in this comprehensive review article our main intension to focus on the Nanoscience and Nanotechnology enabled integrated analysis of various nanostructure utilizes smart biosensor implementations in diagnostics field of cancer treatment via Internet of healthcare things and mobile things (IoHT and IoMT) [17] of details machine learning operating system of biosensor activities are depicted in Fig. 4 [18] . In addition to this, finally a mobile friendly user interface (UI) application was developed for medical inspections and healthcare perception.…”
Section: Role Of Electrochemical Biosensors In Sars-cov-2/covid-19 Co...mentioning
“…A new class of wearable skin-interfaced sensors with the characteristics of lightness, flexibility, and portability have found powerful applications in non-invasive physiological monitoring [ 37 , 38 ]. Examples of those innovative technologies include ultra-thin and stretchable biosensors such as e-tattoos and patches with excellent compliance with the skin curvatures and body movements to provide additional patient comfort, skin safety, and signal accuracy [ 24 , 35 , 39 , 40 , 41 ].…”
Wearables are valuable solutions for monitoring a variety of physiological parameters. Their application in cardiorespiratory monitoring may significantly impact global health problems and the economic burden related to cardiovascular and respiratory diseases. Here, we describe a soft biosensor capable of monitoring heart (HR) and respiratory (RR) rates simultaneously. We show that a skin-interfaced biosensor based on fiber optics (i.e., the smart patch) is capable of estimating HR and RR by detecting local ribcage strain caused by breathing and heart beating. The system addresses some of the main technical challenges that limit the wide-scale use of wearables, such as the simultaneous monitoring of HR and RR via single sensing modalities, their limited skin compliance, and low sensitivity. We demonstrate that the smart patch estimates HR and RR with high fidelity under different respiratory conditions and common daily body positions. We highlight the system potentiality of real-time cardiorespiratory monitoring in a broad range of home settings.
“…Biosensors are analytical devices consisting of a biological receptor acting as sensing element and a transducer that converts a biological response into an optical or electrochemical signal for the detection and quantification of a target analyte (Gutiérrez et al, 2015 ). Due to their small size and low cost, biosensors can be integrated into wide sensor networks (Hart & Martinez, 2006 ; Phan et al, 2022 ). Biosensors represent a good alternative to the conventional assay methods requiring complex, offline instruments such as gas chromatography, liquid chromatography, and mass spectrometry.…”
Biosensors are low‐cost and low‐maintenance alternatives to conventional analytical techniques for biomedical, industrial and environmental applications. Biosensors based on whole microorganisms can be genetically engineered to attain high sensitivity and specificity for the detection of selected analytes. While bacteria‐based biosensors have been extensively reported, there is a recent interest in yeast‐based biosensors, combining the microbial with the eukaryotic advantages, including possession of specific receptors, stability and high robustness. Here, we describe recently reported yeast‐based biosensors highlighting their biological and technical features together with their status of development, that is, laboratory or prototype. Notably, most yeast‐based biosensors are still in the early developmental stage, with only a few prototypes tested for real applications. Open challenges, including systematic use of advanced molecular and biotechnological tools, bioprospecting, and implementation of yeast‐based biosensors in electrochemical setup, are discussed to find possible solutions for overcoming bottlenecks and promote real‐world application of yeast‐based biosensors.
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