A flexible piezoelectric micromachined ultrasound transducer

Yang, Yi; Tian, He; Yan, Bing; Sun, Hui; Wu, Can; Shu, Yi; Wang, Ligang; Ren, Tian‐Ling

doi:10.1039/c3ra44619k

Cited by 35 publications

(25 citation statements)

References 12 publications

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“…Although the extracorporeal method would allow for non-invasive neuromodulation, an implantable transducer would allow for modulation without the subject maintaining a rigidly fixed head position throughout the application. Recent developments to minimize the envelope of the ultrasound transducers has led to the fabrication of miniaturized patch transducers (Bhuyan et al, 2011 ; Yang et al, 2013 ; Wang et al, 2015 ). These phased array patch transducers are thin (~1 mm in thickness) and flexible allowing either subcutaneous or subcranial implantation either giving researchers the ability to target multiple brain regions.…”

Section: Discussionmentioning

confidence: 99%

“…These phased array patch transducers are thin (~1 mm in thickness) and flexible allowing either subcutaneous or subcranial implantation either giving researchers the ability to target multiple brain regions. As the transducers are phased arrays, electronic steering of the individual elements allows researchers to target various brain regions through electric steering of their elements (Bhuyan et al, 2011 ; Yang et al, 2013 ; Wang et al, 2015 ). While extracorporeal devices are useful in clinical or research settings, an implantable device would give patients greater independence and mobility.…”

Section: Discussionmentioning

confidence: 99%

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Toward a Cognitive Neural Prosthesis Using Focused Ultrasound

et al. 2017

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Non-invasive brain stimulation using focused ultrasound has many potential applications as a research and clinical tool, including its incorporation as either an extracorporeal or implantable neural prosthetic. To this end, we investigated the effect of focused ultrasound (FUS) combined with systemically administered microbubbles on visual-motor decision-making behavior in monkeys. We applied FUS to the putamen in one hemisphere to open the blood-brain barrier (BBB), and then tested behavioral performance 3–4 h later. On days when the monkeys were treated with FUS, their decisions were faster and more accurate than days without sonication. The performance improvement suggested both a shift in the decision criterion and an enhancement of the use of sensory evidence in the decision process. FUS also interacted with the effect of a low dose of haloperidol. The findings indicate that a two-minute application of FUS can have a sustained impact on performance of complex cognitive tasks, and may increase the efficacy of psychoactive medications. The results lend further support to the idea that the dorsal striatum plays an integral role in evidence- and reward-based decision-making, and provide motivation for incorporating FUS into cognitive neural prosthetic devices.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Toward a Cognitive Neural Prosthesis Using Focused Ultrasound

et al. 2017

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“…Available feasible strategies for fabricating flexible piezoelectric micro-ultrasonic transducers that can be mainly divided into two categories: island-bridge connection techniques and transfer printing techniques. In the former case, the flexibility is achieved by connecting bulk piezoelectric ceramic islands to each other using polymer joints or embedding piezoelectric ceramics into patterned polymer holes [23][24][25][26][27]. This island-bridge connection technique is based on micromachining fabrication processes, including standard photolithography, deposition and etching, which require expensive equipment, hazardous chemical substances, photomasks, and a clean room ambient.…”

Section: Introductionmentioning

confidence: 99%

Low Temperature Adhesive Bonding-Based Fabrication of an Air-Borne Flexible Piezoelectric Micromachined Ultrasonic Transducer

Liu

2020

Sensors

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This paper presents the development of a flexible piezoelectric micromachined ultrasonic transducer (PMUT) that can conform to flat, concave, and convex surfaces and work in air. The PMUT consists of an Ag-coated polyvinylidene fluoride (PVDF) film mounted onto a laser-manipulated polymer substrate. A low temperature (<100 °C) adhesive bonding technique is adopted in the fabrication process. Finite element analysis (FEA) is implemented to confirm the capability of predicting the resonant frequency of composite diaphragms and optimizing the device. The manufactured PMUT exhibits a center frequency of 198 kHz with a wide operational bandwidth. Its acoustic performance is demonstrated by transmitting and receiving ultrasound in air on curved surface. The conclusions from this study indicate the proposed PMUT has great potential in ultrasonic and wearable devices applications.

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“…[8][9][10][11][12][13][14][15][16][17] In the past, many authors, including our group have reported lead-based materials for suitable pressure sensors in the low and high-pressure range, where a signicant change in dielectric constant, piezoelectric coefficient and capacitive reactance was observed as a function of pressure. [1][2][3][5][6][7]13,[18][19][20][21][22][23][24][25][26] However, the effect of pressure on change in dielectric constant was not as signicant that it can be realized for real high-pressure sensor devices. Another drawback was the linearity in dielectric constant as a function of pressure.…”

Section: Introductionmentioning

confidence: 99%