A first population-based long-term outcome study in adults with repaired tetralogy of Fallot in Malta

Caruana, Maryanne; Grech, Victor

doi:10.1111/chd.12439

Cited by 6 publications

(4 citation statements)

References 22 publications

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“…While several studies have specifically analysed TOF patient mortality following surgical repair of the defect [11, 13–15], others have focused on overall CHD mortality [16–18]. In addition, some other TOF studies report on long-term outcome and survival analyses [19–23].…”

Section: Introductionmentioning

confidence: 99%

Tetralogy of Fallot in Spain: a nationwide registry-based mortality study across 36 years

Llamosas-Falcón

Bermejo‐Sánchez

Sánchez-Díaz

et al. 2019

Orphanet J Rare Dis

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Background Tetralogy of Fallot (TOF) is the most frequent cyanotic congenital heart defect. TOF mortality has fallen remarkably in recent years due to therapeutic advances. Accordingly, the aim of this study was to assess temporal and spatial variability in TOF-related mortality in Spain across the period 1981–2016, using data drawn from the nationwide population-based registry. Methods Annual deaths due to TOF were sourced from the Spanish National Institute of Statistics database by reference to International Classification of Diseases (ICD), 9th and 10th Revision codes, namely, ICD-9 code 745.2 (period 1981–1998) and ICD-10 code Q21.3 (period 1999–2016). Age-specific and age-adjusted mortality rates were calculated, as were standardised mortality ratios (SMRs) by province, district and municipality for the period 1999–2016. Results A total of 1035 deaths were attributed to TOF (57.78% of them were men and 42.22% were women). The age-adjusted mortality rate ranged from 0.75 per 1,000,000 inhabitants (95% confidence interval [CI]: 0–1.36) in 1981 to 0.03 per 1,000,000 (95% CI: 0.01–0.06) in 2016 for both sexes. In 2011, there was a change in the mortality trend, with a significant decrease of 49.22% per year ( p < 0.001). In terms of geographical analysis, some areas with a significantly higher risk of TOF mortality were identified in the south of Spain, though no specific spatial pattern was in evidence. Conclusion The decrease in TOF mortality may be related to improvements in diagnostic and treatment techniques. More studies are needed to analyse regions with a higher mortality risk, in order to improve medical planning and resource allocation, and identify risk factors and preventive measures.

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Section: Introductionmentioning

confidence: 99%

Tetralogy of Fallot in Spain: a nationwide registry-based mortality study across 36 years

Llamosas-Falcón

Bermejo‐Sánchez

Sánchez-Díaz

et al. 2019

Orphanet J Rare Dis

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“…A better understanding of the disease, refinement in the diagnostic process and progress in technology and surgical techniques allowed to operate these children at increasingly younger ages: the recommended age for correction is at 6 months of life. Current operative mortality is 2 % or lower 27,28 and long-term follow-up, at 40 years, has shown a survival rate of 77.5 %, with practically normal quality of life in most cases. 29…”

Section: Tetralogy Of Fallotmentioning

confidence: 99%

Congenital heart disease in 2018

Vázquez-Antona¹,

Alva-Espinosa²,

Yáñez-Gutiérrez³

et al. 2023

GMM

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We present an update of the most relevant advances of three-dimensional echocardiography for the diagnosis of congenital heart diseases. The evolution of its treatment is analyzed, showing the results obtained in recent years. The functional and structural changes experienced in women with congenital heart disease during pregnancy are discussed, as well as the main health risks and the importance of teamwork in healthcare to treat these patients. Finally, we provide a review on the current situation in Mexico and outline some improvement recommendations.

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“…Una mejor comprensión de la enfermedad, el refinamiento en el proceso diagnóstico y el progreso en la tecnología y técnicas quirúrgicas permitió operar a estos niños a edades cada vez más tempranas: la edad recomendada para la corrección es a los seis meses de vida. La mortalidad operatoria actual es de 2 % o menor 27,28 y el seguimiento a largo plazo, a 40 años, ha demostrado una supervivencia de 77.5 %, con una calidad de vida prácticamente normal en la mayoría de los casos. 29…”

Section: Tetralogía De Fallotunclassified

Las cardiopatías congénitas en el 2018

Vázquez-Antona

Alva-Espinosa

Yáñez-Gutiérrez

et al. 2018

GMM

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Se presenta una actualización de los avances más relevantes de la ecocardiografía tridimensional para el diagnóstico de las cardiopatías congénitas. Se analiza la evolución de su tratamiento y se describen los resultados obtenidos en los últimos años. En el tema de la mujer embarazada con cardiopatía congénita se subrayan los cambios funcionales y estructurales durante el embarazo, así como los riesgos por considerar y la importancia del trabajo en equipo para tratar a estas enfermas. Finalmente se aportan datos de la situación en México y las medidas recomendadas para mejorarla.

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A first population-based long-term outcome study in adults with repaired tetralogy of Fallot in Malta

Abstract: Although survival after tetralogy of Fallot repair in contemporary patients is very good, cardiac death can occur at any stage and structural reintervention is common. Regular follow-up with imaging and rhythm monitoring remains of utmost importance in all patients.

Cited by 6 publications

References 22 publications

Tetralogy of Fallot in Spain: a nationwide registry-based mortality study across 36 years

Tetralogy of Fallot in Spain: a nationwide registry-based mortality study across 36 years

Congenital heart disease in 2018

Las cardiopatías congénitas en el 2018

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