A fatal case of pure ethanol ingestion

Hieda, Yoko; Takeshita, Hitoshi; Fujihara, Junko; Takayama, Kōji

doi:10.1016/j.forsciint.2004.08.011

Cited by 7 publications

(6 citation statements)

References 15 publications

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“…Most of these victims had developed abdominal symptoms such as pain and vomiting but acute oesophagus-gastric lesions have not been reported. A single fatal case by ingestion of 1 l of pure ethanol has been reported in a man whose autopsy showed extensive pancreatic oedema and necrosis but only scattered petechial haemorrhages throughout the gastric mucosa, very soft tissue injuries compared to our case [19].…”

Section: Discussionsupporting

confidence: 46%

Severe necrosis of oesophageal and gastric mucosa in fatal methanol poisoning

Cascallana¹,

Gordo²,

Montes³

2012

Forensic Science International

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Section: Discussionsupporting

confidence: 46%

Severe necrosis of oesophageal and gastric mucosa in fatal methanol poisoning

Cascallana¹,

Gordo²,

Montes³

2012

Forensic Science International

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“…Blood chemistry analysis of Serum Glutamic Oxalocetic Transaminase (SGOT), Serum Glutamic Pyruvic Transaminase (SGPT) and Gamma Glutamyl Transferase (GGT) assessed liver cell damages. 6 We used Diasys ALAT (GPT) FS reagents for SGPT levels, Diasys ASAT (GOT) FS reagents for SGOT levels, Diasys Gamma-GT FS reagents for GGT levels to measure serum liver enzyme levels. Measurement of SGOT, SGPT, GGT levels using these reagents was diagnostic for quantitative in vitro measurement in serum or plasma with photometric systems.…”

Section: Determination Of Liver and Kidney Cell Damagementioning

confidence: 99%

The analysis of cell damage of liver and kidney among alcoholics in Yogyakarta, Indonesia

et al. 2019

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Alcohol tends to disrupt the organs function of human body, even can cause serious and chronic damage. In Indonesia, the data on cell damage taken from organs including the livers and kidneys among alcoholics are still practically unknown. The aim of this study was to compare the differences of organs' cell disturbance between alcoholics and non-alcoholics in Yogyakarta, Indonesia. A crosssectional study was conducted among 197 people in Yogyakarta, including 96 alcoholics and 101 non-alcoholics. The material of the study was taken from venous blood samples. A kinetic photometric test was conducted to obtain data on blood-chemical markers' value of livers (SGOT, SGPT, and GGT), and kidneys (BUN and serum creatinine). The data werethen analyzed by Chi square test.From a total of 96 alcoholics, 83.6% are males and 16.4% are females who consumed alcohol for an average of 16 years, with 51.6% routinely consuming it daily. The kind of alcohol they consumed was singlebrand (59.8%). Based on 25 th percentile (GGT), on 50 th percentile (SGOT, GGT), and on 75 th percentile (SGPT, GGT), the alcoholics had higher proportion value of liver marker disturbance than non-alcoholics which was statistically significant (p<0.05). Based on the 50 th and 75 th percentiles, the alcoholics also had higher proportion value on kidney marker (BUN) damage than non-alcoholics which was statistically significant (p<0.05). There were significant differences in GFR values between males and females (p<0.05), males had kidney cell damage 7.9 times more than females. There was no significant difference in the value of GFR between alcoholics and nonalcoholics. In conclusion, the alcoholics hassignificantly higher proportion value of blood-chemical markers than that non-alcoholics. The GFR values between males and females are also significantly different, and males had kidney cell damage 7.9 times more than that of females. ABSTRAK Alkohol dapat merusak fungsi organ tubuh manusia, bahkan dapat menyebabkan kerusakan serius dan kronik. Di Indonesia, data kerusakan sel yang diambil dari organ hati dan ginjal pada alkoholik tidak diketahui. Tujuan penelitian ini adalah membandingkan perbedaan gangguan sel pada organ antara alkoholik dan nonalkoholik di Yogyakarta, Indonesia. Studi potong lintang dilakukan pada 197 orang di Yogyakarta, terdiri dari 96 alkoholik dan 101 non-alkoholik. Material diambil dari sampel darah vena. Tes fotometrik kinetik dilakukan untuk mendapatkan data nilai penanda kimia darah pada hati (SGOT, SGPT, dan GGT), dan ginjal (BUN dan kreatinin serum). Data kemudian dianalisis menggunakan uji Chi square.Dari total 96 alkoholik, 83,6% adalah laki-laki dan 16,4% adalah perempuan, yang rata-rata mengkonsumsi alkohol selama 16 tahun, dan 51,6% rutin mengkonsumsi tiap hari. Macam alkohol yang dikonsumsi adalah satu merk (59,8%). Berdasar 25 persentil (GGT), 50persentil (SGOT, GGT), dan 75 persentil (SGPT, GGT), alkoholik mempunyai proporsi yang lebih tinggi dan bermakna secara statistik terhadap gangguan nilai penanda hepar dibandingkan...

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“…At this high dose, the alcohol itself exerts a sedative and depressive effect on neural cells in the respiratory center of the midbrain. Therefore, a putative mechanism of death by alcohol intoxication is considered suppression of respiratory function regulated by the medulla oblongata with concomitant central nervous hypoxia [ 16 – 18 ]. However, the cause-effect relationship between alcohol and death is ambiguous in sauna deaths and it is difficult to assess the significance of lower BACs of between 0.08 and0.29%.…”

Section: Discussionmentioning

confidence: 99%

Characteristics of sauna deaths in Korea in relation to different blood alcohol concentrations

Yang

Lee

et al. 2018

Forensic Sci Med Pathol

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Although the benefits of sauna bathing have been demonstrated in epidemiological studies, sauna deaths have been reported. The aim of this study was to determine the demographic and forensic characteristics associated with different blood alcohol concentrations (BACs) in sauna deaths in Korea. In this retrospective analysis, data were collected from a nationwide pool in Korea between January 2008 and December 2015 to determine the role of alcohol intoxication in sauna deaths based on the subjects’ BAC and to evaluate the demographic and forensic characteristics associated with different BACs. One hundred and three deaths were classified into 2 groups: the non-intoxication (NI) group (BAC,<0.08%; n = 27) and the intoxication (I) group (BAC,≥0.08%; n = 76). Demographic and forensic characteristics were compared between the groups using a multinomial logistic regression analysis. The proportions of decedents who were male (odds ratio: 17.4, 95.0% confidence interval: 3.8–79.8) and in a prone position at the scene of death (odds ratio: 11.3, 95.0% confidence interval: 2.1–60.1) were significantly higher (P < 0.001 and P < 0.05, retrospectively) in the I group than in the NI group. However, no significant differences were observed with respect to obesity, coronary artery narrowing, and liver pathology. Sauna deaths exhibited different characteristics according to BACs detected at autopsy. The differences in sauna deaths between the I and NI groups may have implications for the targeted prevention of sauna deaths associated with alcohol consumption.

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A fatal case of pure ethanol ingestion

Cited by 7 publications

References 15 publications

Severe necrosis of oesophageal and gastric mucosa in fatal methanol poisoning

Severe necrosis of oesophageal and gastric mucosa in fatal methanol poisoning

The analysis of cell damage of liver and kidney among alcoholics in Yogyakarta, Indonesia

Characteristics of sauna deaths in Korea in relation to different blood alcohol concentrations

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