A facile technique to prepare biodegradable coaxial electrospun nanofibers for controlled release of bioactive agents

Jiang, Hongliang; Hu, Yingqian; Li, Yan; Zhao, Pengcheng; Zhu, Kun; Chen, Weiliain

doi:10.1016/j.jconrel.2005.08.006

Cited by 482 publications

(307 citation statements)

References 22 publications

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“…Coaxial electrospinning [82][83][84][85][86] produces core/shell bers by using a "coaxial" or concentric needle arrangement, which features an inner and an outer channel to separate two or more solutions, Fig. 4B.…”

Section: Coaxial Electrospinning Controls Active Agent Releasementioning

confidence: 99%

Designing electrospun nanofiber mats to promote wound healing – a review

2013

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Current strategies to treat chronic wounds offer limited relief to the 7.75 million patients who suffer from burns or chronic skin ulcers. Thus, as long as chronic wounds remain a global healthcare problem, the development of alternate treatments remain desperately needed. This review explores the recent strategies employed to tailor electrospun nanofiber mats towards accelerating the wound healing process. Porous nanofiber mats readily produced by the electrospinning process offer a promising solution to the management of wounds. The matrix chemistry, surface functionality, and mat degradation rate all can be fine-tuned to govern the interactions that occur at the materials-biology interface. In this review, first we briefly discuss the wound healing process and then highlight recent advances in drug release, biologics encapsulation, and antibacterial activity that have been demonstrated via electrospinning. While this versatile biomaterial has shown much progress, commercializing nanofiber mats that fully address the needs of an individual patient remains an ambitious challenge.

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Section: Coaxial Electrospinning Controls Active Agent Releasementioning

confidence: 99%

Designing electrospun nanofiber mats to promote wound healing – a review

2013

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“…55 Koaksiyel nanolif elde edilmesi yönteminde iki ya da daha fazla polimer çözeltisi elektro-çekim cihazının koaksiyel kapiler besleme ünitesinden geçerek toplama levhasına çekirdek-kabuk (coreshell) yapısında nanolif şeklinde toplanmaktadır (Şekil 3). 56 Koaksiyel elektro-çekim 2003 yılında bulunmuş ve hızla popüler hâle gelmiştir. Bu şe-kilde elde edilen nanoliflerde dış kısma ilaç yük-lenmesi yapılabilmektedir.…”

Section: Yüksek Voltaj Güç Kaynağıunclassified

Wound Healing and Electrospun Wound Dressings: Review

Tort¹,

Acartürk²

2015

Turkiye Klinikleri J Pharm Sci

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“…These particular structures have promise in use for axially loaded tissue such as ligaments and tendons. Coaxial spinning with two concentric spinnerets has also shown potential for creating composite fibers (Jiang, Hu et al 2005;McCann, Marquez et al 2006). In this process a hybrid fiber with a different core material can be produced.…”

Section: 1 Electrospinningmentioning

confidence: 99%