A facile colorimetric sensor for ultrasensitive and selective detection of Lead(II) in environmental and biological samples based on intrinsic peroxidase-mimic activity of WS2 nanosheets

Tang, Yue; Hu, Yang; Yang, Yadong; Liu, Bangyan; Wu, Yuangen

doi:10.1016/j.aca.2020.01.043

Cited by 52 publications

(20 citation statements)

References 40 publications

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“…Chitosan modified MoSe 2 showed optimal POD activity at pH 3.5 and 55 °C temperature; higher pH or lower temperatures were linked with lower activity [ 28 ]. The presence of Fe 2+ ion increased POD activity of WS 2 NZs [ 62 ], whereas the presence of Pb 2+ ion hindered it [ 63 ].…”

Section: Tmdc Nanozyme: Synthesis Enzymatic Activities Regulatory Factorsmentioning

confidence: 99%

Transition Metal Dichalcogenides (TMDC)-Based Nanozymes for Biosensing and Therapeutic Applications

et al. 2022

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Nanozymes, a type of nanomaterial with enzyme-like properties, are a promising alternative to natural enzymes. In particular, transition metal dichalcogenides (TMDCs, with the general formula MX2, where M represents a transition metal and X is a chalcogen element)-based nanozymes have demonstrated exceptional potential in the healthcare and diagnostic sectors. TMDCs have different enzymatic properties due to their unique nano-architecture, high surface area, and semiconducting properties with tunable band gaps. Furthermore, the compatibility of TMDCs with various chemical or physical modification strategies provide a simple and scalable way to engineer and control their enzymatic activity. Here, we discuss recent advances made with TMDC-based nanozymes for biosensing and therapeutic applications. We also discuss their synthesis strategies, various enzymatic properties, current challenges, and the outlook for future developments in this field.

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Section: Tmdc Nanozyme: Synthesis Enzymatic Activities Regulatory Factorsmentioning

confidence: 99%

Transition Metal Dichalcogenides (TMDC)-Based Nanozymes for Biosensing and Therapeutic Applications

et al. 2022

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“…The sensing of H 2 O 2 is quite important in the research of nanozyme, not only for the physiological effects of H 2 O 2 but also due to the fact that detection of H 2 O 2 is usually coupled with the sensing of other biomolecules or chemical particles such as biothiols [17], dopamine [18], metal ions [19][20][21], histidine, and Cu 2+ [22], which can inhibit or stabilize the peroxidase-like activity of nanozymes and indirectly mediate the oxidative generation of TMB (Figure 1). Furthermore, some biomolecules like cholesterol [23], glucose [24], and galactose [25] can be oxidized by their oxidases to generate H 2 O 2 ; so, combining these two reactions can help quantify the molecules easily (Figure 1).…”

Section: Application Of Nanozyme In Medicinementioning

confidence: 99%

Therapeutic Applications of Nanozymes in Chronic Inflammatory Diseases

Wang

Cui

Wang

et al. 2021

BioMed Research International

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Since the discovery of horseradish peroxidase-like activity of magnetite nanoparticles in 2007, many researchers have investigated different types of nanoparticles that show enzyme-like activities, namely, nanozymes. Nanozymes possess high efficiency, stability, and low production costs compared to natural enzymes. Thus, nanozymes have already been widely studied in various domains including medical science, food industry, chemical engineering, and agriculture. This review presents the utilization of nanozymes in medicine and focuses particularly on their therapeutic applications in chronic inflammatory diseases because of their antioxidant-like activity. Furthermore, the treatment of chronic inflammatory diseases with nanozymes of different materials was introduced emphatically.

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“…The multifunctional enzymatic properties of hybridized 2D NMs provide valuable opportunities to develop advanced biosensors. By taking advantage of POD-/OD-like activity of 2D NMs, the colorimetric assays for other analytes like AA (Wang X. H. et al, 2017;Sun et al, 2020), biothiols [e.g., GSH (Liu et al, 2017;Ge et al, 2019;Liu X. L. et al, 2019), cysteine (Liu X. L. et al, 2019), and homocysteine (Liu X. L. et al, 2019)], xanthine (Cai et al, 2018b;Wu et al, 2018;Li et al, 2019), dopamine (Dutta et al, 2015;Ivanova et al, 2019), cholesterol (Zhang et al, 2017), acetylcholinesterase (Yan et al, 2017), cancer cells (Tao et al, 2013;Zhang L. N. et al, 2014;Qi et al, 2016), ions [e.g., S 2− (Liu et al, 2020), Fe 2+ (Wang et al, 2016), and Pb 2+ (Tang et al, 2020)], have also been established by different groups. The colorimetric biosensing based on 2D nanozymes continues to be a rapidly growing field.…”

Section: Biosensorsmentioning

confidence: 99%

Two-Dimensional Nanomaterials With Enzyme-Like Properties for Biomedical Applications

Cai

Yang

2020

Front. Chem.

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Recently, remarkable progress has been made in nanozyme research due to the rapid development of nanomaterials. Two-dimensional nanomaterials such as metal nanosheets, graphene-based materials, transition metal oxides/dichalcogenides, etc., provide enhanced physical and chemical functionality owing to their ultrathin structures, high surface-to-volume ratios, and surface charges. They have also been found to have high catalytic activities in terms of natural enzymes such as peroxidase, oxidase, catalase, and superoxide dismutase. This review provides an overview of the recent progress of nanozymes based on two-dimensional nanomaterials, with an emphasis on their synthetic strategies, hybridization, catalytic properties, and biomedical applications. Finally, the future challenges and prospects for this research are discussed.

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A facile colorimetric sensor for ultrasensitive and selective detection of Lead(II) in environmental and biological samples based on intrinsic peroxidase-mimic activity of WS2 nanosheets

Cited by 52 publications

References 40 publications

Transition Metal Dichalcogenides (TMDC)-Based Nanozymes for Biosensing and Therapeutic Applications

Transition Metal Dichalcogenides (TMDC)-Based Nanozymes for Biosensing and Therapeutic Applications

Therapeutic Applications of Nanozymes in Chronic Inflammatory Diseases

Two-Dimensional Nanomaterials With Enzyme-Like Properties for Biomedical Applications

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