A facile and general method for synthesis of antibiotic-free protein-based hydrogel: Wound dressing for the eradication of drug-resistant bacteria and biofilms

Ouyang, Jun; Bu, Qingyue; Tao, Na; Chen, Miao; Liu, Haijun; Zhou, Jun; Liu, Jinggong; Deng, Bo; Kong, Na; Zhang, Xingcai; Chen, Tianfeng; Cao, Yihai; Tao, Wei

doi:10.1016/j.bioactmat.2022.03.033

Cited by 66 publications

(48 citation statements)

References 40 publications

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“…When there is a bacterial infection in a wound, it mainly prolongs the healing process. This is due to the formation of the organized structure of bacterial biofilms that adhere to the tissue and biomaterial and prevent the effect of antibiotics [ 43 ]. Typically, the antibiotics used act on bacteria by disrupting the function of the bacteria’s structure, such as walls, or their metabolic pathways [ 44 ].…”

Section: Discussionmentioning

confidence: 99%

Insights into the Design of Polyurethane Dressings Suitable for the Stages of Skin Wound-Healing: A Systematic Review

et al. 2022

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Dressings made with polyurethanes have been found to exhibit good and varied biological properties that make them good candidates for this application. However, as has been seen, the wound-healing process is complex, which includes four different stages. So far, the design and evaluation of polyurethane for wound dressing has focused on achieving good properties (mechanical, physicochemical, and biological), but each of them separates from the others or even directed at only one of the stages of skin wound-healing. Therefore, the aim of this systematic review is to explore the applications of polyurethanes in wound dressings and to determine whether could be designed to cover more than one stage of skin wound-healing. The PRISMA guidelines were followed. The current research in this field does not consider each stage separately, and the design of polyurethane dressings is focused on covering all the stages of wound healing with a single material but is necessary to replace polyurethanes in short periods of time. Additionally, little emphasis is placed on the hemostasis stage and further characterization of polyurethanes is still needed to correlate mechanical and physicochemical properties with biological properties at each stage of the wound-healing. Current research demonstrates an effort to characterize the materials physiochemically and mechanically, but in terms of their biological properties, most of the literature is based on the performance of histological tests of explants morphologically probing the compromised tissues, which give an indication of the potential use of polyurethanes in the generation of wound-healing dressings.

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Section: Discussionmentioning

confidence: 99%

Insights into the Design of Polyurethane Dressings Suitable for the Stages of Skin Wound-Healing: A Systematic Review

et al. 2022

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“…15 Since then, researchers have reported bio lms in almost all natural and industrial ecosystems, especially in infectious diseases. [16][17][18][19][20] In this study, we used a combination of bibliometric and visualized analyses to grasp the current state of the eld on helicobacter bio lms research. These articles re ected major advances and annual publications' trend about helicobacter bio lm during the last two decades.…”

Section: Discussionmentioning

confidence: 99%

Global trends of Helicobacter pylori biofilm research in the past two decades: A bibliometric study

Wang

Xie

2022

Preprint

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Background: Helicobacter pylori biofilm formation is a key factor of refractory helicobacter pylori infection. This study aimed to access the research trends of helicobacter pylori biofilm.Methods: Publications from 1998 to 2022 were retrieved from the Web of Science Core Collection database. Different kinds of software, EXCEL, VOSviewer, and the online bibliometric analysis platform were used to evaluate and visualize the bibliometric data.Results: A total of 154 publications were finally identified, and the annual number of publications showed a rising trend. The China made the greatest contributions to this research field, while the journal of Helicobacter was the most productive journal. Grande rossella published the most papers, and the most productive institution was G dannunzio University. Co-occurrence network maps revealed that the keyword of “Helicobacter pylori” ranked first in research field, and the keyword of “biofilm formation” and “in vitro” began to appear in the past 3 to 5 years.Conclusion: The annual number of publications on helicobacter pylori biofilm have grown steadily in the past two decades and will continue to grow. Future research hot spots will domain in the establishment of helicobacter pylori biofilm in vitro model and mechanism of helicobacter pylori biofilm formation.

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“…430 Since then, an increasing number of biomaterials for tissue engineering have been developed, including metals, inorganic ceramics, polymer materials, composites, etc. [431][432][433][434][435][436][437][438] In the past few years, LDHs have emerged as a potential candidate for tissue engineering applications. Significant achievements have been made in bone repair, wound healing, nerve regeneration, dental restoration and cardiac repair, greatly promoting the development of tissue engineering.…”

Section: Tissue Engineeringmentioning

confidence: 99%

Layered double hydroxide-based nanomaterials for biomedical applications

et al. 2022

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A facile and general method for synthesis of antibiotic-free protein-based hydrogel: Wound dressing for the eradication of drug-resistant bacteria and biofilms

Cited by 66 publications

References 40 publications

Insights into the Design of Polyurethane Dressings Suitable for the Stages of Skin Wound-Healing: A Systematic Review

Insights into the Design of Polyurethane Dressings Suitable for the Stages of Skin Wound-Healing: A Systematic Review

Global trends of Helicobacter pylori biofilm research in the past two decades: A bibliometric study

Layered double hydroxide-based nanomaterials for biomedical applications

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