A dynamic finite element model of human cervical spine with in vivo kinematic validation

Abstract

Most previous cervical spine finite element (FE) models were validated using in vitro cadaver measurement data from literatures. Although in vitro measurement can provide valuable data for model verification, the in vivo mechanical and physiological conditions of the cervical spine during its natural motions cannot be reproduced in vitro. In this study, a human FE model of skull (C0) and spinal vertebrae (C1-T1) was developed. The in vivo kinematic characteristics of head and neck were obtained from optoelectronic system, and used for the validation of the FE model. The simulation results showed good agreement with the measured data in left/right lateral bending and left/right axial rotation, while discrepancy existed during flexion. The predicted segmental cervical vertebral angles were compared against data from previous in vivo experiment, too. Furthermore, the skin shift data from previous study was used to compensate the experimental measurement during flexion and left/right lateral bending. The results showed the model was successfully validated with the in vivo experimental data.

Biomechanical Comparison of Optimal Shapes for the Cervical Intervertebral Fusion Cage for C5–C6 Cervical Fusion Using the Anterior Cervical Plate and Cage (ACPC) Fixation System: A Finite Element Analysis

“…The fifth and sixth cervical vertebral levels (C5–C6) were extracted from the previously reported cervical finite element (FE) model [15]. The fixed element (FE) model of the vertebra consists of an inferior endplate, a superior endplate, a cancellous core, a cortical wall, and a posterior structure.…”

Finite element models of the human shoulder complex: a review of their clinical implications and modelling techniques

“…Different approaches have been used for acquiring the dataset for the geometric construction varying from using literature data [71], average measured data [36] to subject-specific medical imaging data [31,32,39,41,44,45,48,52,53,56,[58][59][60]62,66,68,84]. For geometric construction of bones, the most widely used approach is based on computed tomography (CT) imaging data, for example, the CT image databases for the modelling of the cervical spine and hip joint in our previous studies [85,86]. While in some studies the bone geometry was measured directly in cadaveric dissections or used the datasets from literature [32,39,48,56].…”

“…In addition, the FE simulation analyses in most of the studies were only limited to the static or quasi‐static condition. We have applied dynamic FE simulation analysis to study cervical spine and foot biomechanics , and have an ongoing study to use dynamic FE analysis to investigate the in vivo functioning of the shoulder complex. Physiologically more realistic loading and boundary conditions are likely to provide the best way to predict the tissue stress environment in vivo.…”

“…The positions and orientations of bones or joints captured from motion analysis systems or X‐ray systems could provide useful datasets to validate FE simulations in vivo. Recently, we have successfully used this method to validate a FE model of cervical spine . Advances in medical imaging domains (e.g.…”

Adaptive load feedback robustly signals force dynamics in robotic model of Carausius morosus stepping

“…In the present study, we are interested in measuring the minute strain of the leg segments as the leg steps, but to reduce runtime, multi-body physics simulators almost always model segments as “rigid bodies” that cannot bend. Computational modeling techniques such as Finite Element Analysis (FEA) are extremely useful for predicting how complex shapes such as insect leg segments would strain when stressed and have yielded valuable insights into how insects detect strain ( Kaliyamoorthy et al, 2001 ; Wang et al, 2014 , 2019 ; Noda et al, 2018 ; Dinges et al, 2022 ). However, determining and applying a realistic stress profile to the model is a challenging problem, which a robotic model inherently solves.…”