A dual-site and dual-turn-on fluorescence probe for imaging mitochondrial HClO and SO2

Bao, Xiazhen; Ai, Kaili; Cao, Xuehui; Chen, Dongping; Zhou, Bo; Huo, Congde

doi:10.1016/j.dyepig.2021.109928

Cited by 17 publications

(8 citation statements)

References 52 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…In 2021, Bao et al [46] . designed a dual‐response fluorescent probe 10 for HClO and SO 2 , which was composed of carbon‐carbon double bonds bridging phenothiazine and benzoindole, among which electron‐rich phenothiazine and the skeleton of electron‐deficient benzoindole were the recognition group of HClO and SO 2 , respectively (Figure 10).…”

Section: Fluorescent Probe For Detecting Hclo and Rssmentioning

confidence: 99%

“… The proposed sensing mechanism of probe 10 toward HClO and SO 2 ; Fluorescence imaging of the oxidative stress induced by HClO with probe 10 in living zebrafish. Reprinted with permission from Ref [46] . Copyright 2021, Elsevier Ltd.…”

Section: Fluorescent Probe For Detecting Hclo and Rssmentioning

confidence: 99%

“…In 2021, Bao et al [46] designed a dual-response fluorescent probe 10 for HClO and SO 2 , which was composed of carboncarbon double bonds bridging phenothiazine and benzoindole, among which electron-rich phenothiazine and the skeleton of electron-deficient benzoindole were the recognition group of HClO and SO 2 , respectively (Figure 10). Probe 10 itself had no fluorescence upon excitation at 465 nm, however, upon addition of HClO, the red emission of probe 10 at 590 nm was largely enhanced due to the oxidation of HClO to its sulfoxide.…”

Section: Thioether Oxidation-based Hclo Fluorescent Probesmentioning

confidence: 99%

“…Reprinted with permission from Ref. [46] Copyright 2021, Elsevier Ltd. fluorescence emission peak centered at 525 nm increased, and the color of the solution changed from red to green. After adding excess SO 2 , a new fluorescence peak was observed at 420 nm.…”

Section: Double Bonds Oxidation Cleavage-based Hclo Fluorescent Probesmentioning

confidence: 99%

See 3 more Smart Citations

Design of Dual‐responsive ROS/RSS Fluorescent Probes and Their Application in Bioimaging

Huang

Yue

Yin

et al. 2022

Chemistry An Asian Journal

View full text Add to dashboard Cite

Intracellular redox homeostasis exerts a tremendous influence on pathophysiological fields. In order to maintain the homeostasis of intracellular redox state, reactive oxygen species (ROS) and reactive sulfur species (RSS) react and transform with each other, and their levels also directly reflect the degree of oxidative stress and disease. To understand the correlation and pathophysiological effects of these two signaling molecules in oxidative stress, unique fluorescence imaging tools are required. Fluorescent probes have become an indispensable detection tool in modern scientific research and disease diagnosis. Currently, there are many fluorescent probes for detecting ROS or RSS. However, the cellular environment is extremely complex. Dual detection fluorescent probes that can monitor more than one species in a biological environment cause our attention. This review describes dual detection fluorescent probes that can detect ROS and RSS simultaneously or sequentially. This will provide strong support for the study of redox homeostasis.

show abstract

Section: Fluorescent Probe For Detecting Hclo and Rssmentioning

confidence: 99%

Section: Fluorescent Probe For Detecting Hclo and Rssmentioning

confidence: 99%

Section: Thioether Oxidation-based Hclo Fluorescent Probesmentioning

confidence: 99%

Section: Double Bonds Oxidation Cleavage-based Hclo Fluorescent Probesmentioning

confidence: 99%

See 2 more Smart Citations

Design of Dual‐responsive ROS/RSS Fluorescent Probes and Their Application in Bioimaging

Huang

Yue

Yin

et al. 2022

Chemistry An Asian Journal

View full text Add to dashboard Cite

show abstract

“…In recent years, researchers have established a variety of methods to detect SO 2 and FA. Among them, fluorescent probes are widely used in the study of various life phenomena in cells [ 20 , 21 , 22 ] and in vivo due to their advantages of low damage, high specificity, high sensitivity and real-time dynamic imaging [ 23 ]. In previous studies, benzopyranium has been proven to be an efficient structure to detect sulfur dioxide [ 24 , 25 ], and its recyclable and reversible detection with some oxidizing species may yet be realized [ 26 , 27 , 28 ].…”

Section: Introductionmentioning

confidence: 99%

Rational Construction of a Mitochondria-Targeted Reversible Fluorescent Probe with Intramolecular FRET for Ratiometric Monitoring Sulfur Dioxide and Formaldehyde

Lyu¹,

Wang²,

Zhang³

2022

Biosensors

View full text Add to dashboard Cite

Sulfur dioxide (SO2) and formaldehyde (FA) are important species that maintain redox homeostasis in life and are closely related to many physiological and pathological processes. Therefore, it is of great significance to realize the reversible monitoring of them at the intracellular level. Here, we synthesized a reversible ratiometric fluorescent probe through a reasonable design, which can sensitively monitor SO2 derivatives and FA, and the detection limit can reach 0.16 μM. The probe can specifically target mitochondria and successfully monitor the fluctuations of SO2 and FA in living cells. It also works well in the detection of SO2 and FA in zebrafish. This high-performance probe is expected to find broad in vitro and in vivo applications.

show abstract

Bifunctional near-infrared fluorescent probe for the selective detection of bisulfite and hypochlorous acid in food, water samples and in vivo

Shang,

Meng,

Zhang

et al. 2023

Analytica Chimica Acta

View full text Add to dashboard Cite

A dual-site and dual-turn-on fluorescence probe for imaging mitochondrial HClO and SO2

Cited by 17 publications

References 52 publications

Design of Dual‐responsive ROS/RSS Fluorescent Probes and Their Application in Bioimaging

Design of Dual‐responsive ROS/RSS Fluorescent Probes and Their Application in Bioimaging

Rational Construction of a Mitochondria-Targeted Reversible Fluorescent Probe with Intramolecular FRET for Ratiometric Monitoring Sulfur Dioxide and Formaldehyde

Bifunctional near-infrared fluorescent probe for the selective detection of bisulfite and hypochlorous acid in food, water samples and in vivo

Contact Info

Product

Resources

About