A Dual Lung-Scanning Technic for Evaluation of Pulmonary Function

Taplin, George V.; Poe, Norman D.

doi:10.1148/85.2.365

Cited by 55 publications

(13 citation statements)

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“…Subsequently, with the implementation of ventilation scanning in 1970, the accuracy of lung scintigraphy was further improved [4][5][6]. Several large clinical studies, using pulmonary angiography as the reference method, revealed perfusionventilation lung scintigraphy to be a sensitive technique for the detection of pulmonary embolism, but also showed that it had a moderate specificity [7,8].…”

Section: Introductionmentioning

confidence: 99%

The value of lung scintigraphy in the diagnosis of pulmonary embolism

et al. 1993

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The role of lung scintigraphy in the diagnostic management of patients with clinically suspected pulmonary embolism is reviewed. Evidence is provided that a normal perfusion scan excludes clinically relevant pulmonary embolism, and that a high probability lung scan, defined as a segmental perfusion defect with locally normal ventilation, sufficiently confirms the presence of pulmonary embolism in the majority of these patients. Furthermore, this review assesses the possibility of non-invasive tests for the diagnosis or exclusion of venous thromboembolic disease as a means of avoiding pulmonary angiography in patients with lung scan outcomes that are neither normal nor high probability.

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Section: Introductionmentioning

confidence: 99%

The value of lung scintigraphy in the diagnosis of pulmonary embolism

et al. 1993

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“…We called this cinematographic display of the continuous measurement of inhaled radioaerosol "radioaerosol inhalation lung cinescintigraphy" instead of "radioaerosol inhalation lung scintigraphy or imaging" (Taplin and Poe 1965;Isawa et al 1970).…”

Section: Methodsmentioning

confidence: 99%

“…aerosol; cine-scintigraphy; inhalation; lung; mucociliary clearance Mucociliary activity can be assessed by sequential measurement of a tracer material placed on the airway whether the tracer be a radioactive droplet (Mann and Morrow 1969;Giordano and Holsclaw 1976;Isawa et al 1980), teflon discs (Sackner et al 1973;Wanner et al 1973;Santz Cruz et al 1974;Landa et al 1975;Friedman et al 1977;Goodman et al 1977), or inhaled radioactive particles (Taplin and Poe 1965;Morrow et al 1967;Isawa et al 1970;Albert et al 1973). Acute exposure to cigarette smoke, for example, could almost lead to ciliostasis in a dosedependent manner in the dog trachea , and no mucociliary clearance was demonstrated in two patients with Kartagener's syndrome (Camner et al 1975).…”

mentioning

confidence: 99%

Radioaerosol inhalation lung cine-scintigraphy: a preliminary report.

Isawa

Teshima

Hirano

et al. 1981

Tohoku J. Exp. Med.

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“…Ventilation studies can also be performed using a radioactive aerosol (Taplin & Poe, 1965). Such an aerosol can be labelled using technetium and used in association with pictures performed by a gamma camera.…”

Section: Lung Scanning Radiopharmaceuticals and Techniquementioning

confidence: 99%

Radioisotope scanning of brain, liver, lung and bone with a note on tumour localizing agents

Lavender

1973

Postgraduate Medical Journal

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SummaryRadioisotopic scanning of brain, liver, lungs and the skeleton is briefly reviewed with a survey of recent developments of clinical significance. In brain scanning neoplasm detection rates of greater than 90%O are claimed. The true figure is probably 70-80%. Autopsy data shows a number of false negatives, particularly with vascular lesions. Attempts to make scanning more specific in differentiating neoplasm from vascular lesions by rapid sequence blood flow studies are reviewed.In liver scanning by means of colloids again high success rate is claimed but small metastases are frequently missed and the false negative scan rate is probably quite high.Lung scanning still has its main place in investigating pulmonary embolic disease. Ventilation studies using Xenon 133 are useful, particularly combined with perfusion studies.The various radiopharmaceuticals for use in bone scanning are reviewed. The appearance of technetium labelled phosphate compounds will probably allow much wider use of total skeletal scanning.Research into tumour localizing agents continues, the most recent and interesting being Gallium citrate and labelled bleomycin. Neither agent is predictable however although Gallium may have a place in Hodgkins disease and bronchogenic neoplasm and both may have a place in the detection of cerebral tumours. IntroductionThis brief review is intended to look at some of the more common applications of radioisotope scanning, and also at certain new developments, in their clinical setting. Recent changes in detecting apparatus and in radiopharmaceuticals are widening the scope of scanning procedures, making investigations more specific; this outline may indicate the type of information and the order of accuracy that can be expected from the various investigations covered.

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A Dual Lung-Scanning Technic for Evaluation of Pulmonary Function

Cited by 55 publications

References 0 publications

The value of lung scintigraphy in the diagnosis of pulmonary embolism

The value of lung scintigraphy in the diagnosis of pulmonary embolism

Radioaerosol inhalation lung cine-scintigraphy: a preliminary report.

Radioisotope scanning of brain, liver, lung and bone with a note on tumour localizing agents

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