A dual function electro-optical silicon field-effect transistor molecular sensor

Laksana, Pradhana Jati Budhi; Tsai, Li-Chu; Wei, Tsai-Yin; Lan, Pei-Chi; Chang‐Liao, Kuei‐Shu; Moodley, M.; Chen, Chii-Dong

doi:10.1039/d1tc03374c

Cited by 2 publications

(2 citation statements)

References 27 publications

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“…Bio–NWFET has been reported as a powerful platform for the detection of interactions between bio-molecules [ 16 , 17 ]; however, the use of bio–NWFET in an FET’s optoelectronic function to form a dual-function sensing device is lesser known [ 18 ]. The function has the unique advantages of mass-production semiconductor device technology, miniaturization, low power consumption, and ease of integration [ 19 ].…”

Section: Introductionmentioning

confidence: 99%

“…The function has the unique advantages of mass-production semiconductor device technology, miniaturization, low power consumption, and ease of integration [ 19 ]. In our previous study [ 18 ], we integrated the charge sensing and optical transduction functions of bio-NWFETs for the detection of antibody–antigen interactions using ELISA technology. In this study, we employed quercetin and Cu 2+ ion as molecules for detecting the molecular absorption of metal complexes.…”

Section: Introductionmentioning

confidence: 99%

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Opto Field-Effect Transistors for Detecting Quercetin–Cu2+ Complex

Laksana

Tsai

Chang-cheng

et al. 2022

Sensors

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In this study, we explored the potential of applying biosensors based on silicon nanowire field-effect transistors (bio–NWFETs) as molecular absorption sensors. Using quercetin and Copper (Cu2+) ion as an example, we demonstrated the use of an opto–FET approach for the detection of molecular interactions. We found that photons with wavelengths of 450 nm were absorbed by the molecular complex, with the absorbance level depending on the Cu2+ concentration. Quantitative detection of the molecular absorption of metal complexes was performed for Cu2+ concentrations ranging between 0.1 μM and 100 μM, in which the photon response increased linearly with the copper concentration under optimized bias parameters. Our opto–FET approach showed an improved absorbance compared with that of a commercial ultraviolet-visible spectrophotometry.

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