A dual computed tomography linear accelerator unit for stereotactic radiation therapy: A new approach without cranially fixated stereotactic frames

Uematsu, Minoru; Fukui, Toshiharu; Shioda, Akira; Tokumitsu, Hideyuki; Takai, Kenji; Kojima, Tadaharu; Asai, Yoshiko; Kusano, Shoichi

doi:10.1016/s0360-3016(96)80022-8

Cited by 109 publications

(36 citation statements)

References 10 publications

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“…Capabilities were later developed to facilitate automated registration of digitally reconstructed radiographs (DRRs) generated from the pretreatment CT scans to DRRs generated from the planning CT (Wang et al 2007). Uematsu et al (1996) reported on the treatment of Fig. 13 a An early body frame design constructed by the UCLA group; b a commercial body frame (Leibinger), originally designed by the Heidelberg group Fig. 14 The spinal radiosurgery approach described by Medin et al combined frame-based localization with kV projection image guidance using a mobile radiography unit eight patients with primary or metastatic brain tumors.…”

Section: Image-assisted Frame-based Sbrtmentioning

confidence: 99%

Historical Development of Stereotactic Ablative Radiotherapy

Solberg

Siddon

Kavanagh

2012

Stereotactic Body Radiation Therapy

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Section: Image-assisted Frame-based Sbrtmentioning

confidence: 99%

Historical Development of Stereotactic Ablative Radiotherapy

Solberg

Siddon

Kavanagh

2012

Stereotactic Body Radiation Therapy

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“…In the revival of treatment room imaging for patient setup, the Japanese radiation oncology community played an important pioneering role. The importance of IGRT was clearly recognized by Shirato [18], Takai [19], and Uematsu [20]. Through their early work with prototype instrumentation, interest in IGRT was renewed.…”

Section: Historical Development Of Igrtmentioning

confidence: 99%

“…Early implementations of this concept were pioneered in Japan [20]. CT on rails provides a 3D data set of anatomy before treatment, and it is conceptually similar to CBCT in intent.…”

Section: Ct On Railsmentioning

confidence: 99%

A review of image-guided radiotherapy

Chen

Sharp

Mori³

2009

Radiol Phys Technol

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Image-guided radiotherapy (IGRT) is in the midst of a strong development and implementation cycle, stimulated by pioneering work performed in Japan. We present a review of the rationale, technology, and methodology of image guidance, as well as an overview of current work in IGRT at the Massachusetts General Hospital. The technology is rapidly evolving, and synergisms between the various acquisition approaches are converging to provide unparalleled information on target and normal tissue location and motion. With these new approaches to patient localization, we expect improved clinical results to be forthcoming.

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“…Stereotactic body radiotherapy (SBRT) for extracranial lesions was developed by Blomgren et al 1) and Uematsu et al 2) . SBRT is a highly precise hypofractionated radiotherapy technique in which large doses of radiation are administered to small tumors of the lung and liver for short periods.…”

Section: Introductionmentioning

confidence: 99%

Prognostic Factors for Overall and Disease-specific Survival of Stage I Non-Small-Cell Lung Cancer after Stereotactic Body Radiotherapy: A Retrospective Analysis

Abe

Okada

Shinozaki

et al. 2017

J St. Marianna Univ

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Background: The purpose of this study was to investigate the prognostic factors of stereotactic body radiotherapy (SBRT) for stage I non-small-cell lung cancer (NSCLC) to improve outcomes. Materials and methods: Between 2008 and 2016, 71 patients with medically inoperable stage I NSCLC were treated at our hospital with SBRT (48-55 Gy in 4-5 fractions for peripheral lesions or 60-64 Gy in 8-10 fractions for central lesions). Survival outcomes were analyzed using Kaplan-Meier and cumulative incidence methods. Factors including sex, age, tumor location, tumor size, BED (biologically effective dose) 10, and maximum standardized uptake value (SUVmax) were evaluated with regard to overall survival (OS) and disease-specific survival (DSS) using Cox proportional hazard regression. Results: The median follow-up duration of surviving patients was 33 months (range, 6-81 months). Two-year OS and DSS were 78.5% and 91.5%, respectively. Two-year cumulative local recurrence rate, regional recurrence rate, and distant metastasis rate were 6.8%, 10.9%, and 7.3%, respectively. Multivariate analysis revealed that BED10 and SUVmax were prognostic factors for DSS. Conclusion: Lower BED10 and higher SUVmax were predictors of significantly worse DSS. A higher SUVmax may be considered for intensive treatment to improve outcomes.

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A dual computed tomography linear accelerator unit for stereotactic radiation therapy: A new approach without cranially fixated stereotactic frames

Cited by 109 publications

References 10 publications

Historical Development of Stereotactic Ablative Radiotherapy

Historical Development of Stereotactic Ablative Radiotherapy

A review of image-guided radiotherapy

Prognostic Factors for Overall and Disease-specific Survival of Stage I Non-Small-Cell Lung Cancer after Stereotactic Body Radiotherapy: A Retrospective Analysis

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