A double-blind study comparing safety, tolerability and efficacy of iodixanol 320 mgI/ml and ioxaglate 320 mgI/ml in cerebral arteriography

Palmers, Y; Greef, Danielle De; Grynne, B.; Smits, Jan; Put, E.

doi:10.1016/0720-048x(93)90105-v

Cited by 30 publications

(18 citation statements)

References 18 publications

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“…Many trials compared iso‐osmolar contrast media (IOCM) (Iodixanol) versus low‐osmolar contrast media (LOCM) (Ioversol) and a recent metanalysis of them shows that the incidence of pain and discomfort in general population referred to intra‐arterial arteriography is considered no major than in 20% of the population, with better results for IOCM versus LOCM.…”

Section: Discussionmentioning

confidence: 99%

Discomfort assessment in peripheral angiography: Randomized clinical trial of Iodixanol 270 versus Ioversol 320 in diabetics with critical limb ischemia

Palena

Sacco

Brigato

et al. 2014

Cathet Cardio Intervent

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Section: Discussionmentioning

confidence: 99%

Discomfort assessment in peripheral angiography: Randomized clinical trial of Iodixanol 270 versus Ioversol 320 in diabetics with critical limb ischemia

Palena

Sacco

Brigato

et al. 2014

Cathet Cardio Intervent

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“…23,24 Several studies that have compared the tolerability of the iso-osmolar contrast medium iodixanol with that of lowosmolar contrast medium report that iso-osmolar contrast medium is associated with a decrease in the intensity of discomfort (heat sensations) and pain. [24][25][26][27][28][29][30] Overall, the key issue that becomes important to define for each specialty is the degree of risk that makes the effort needed to screen patients, identify those at risk, and then implement prevention strategies, a requirement despite any impracticality.…”

Section: The Need For Specialty-specific Guidelinesmentioning

confidence: 99%

Contrast-Induced Acute Kidney Injury: Specialty-Specific Protocols for Interventional Radiology, Diagnostic Computed Tomography Radiology, and Interventional Cardiology

Goldfarb

McCullough

McDermott

et al. 2009

Mayo Clinic Proceedings

138

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Contrast-induced acute kidney injury (AKI) (also known as contrast-induced nephropathy) is an abrupt deterioration in renal function that can be associated with use of iodinated contrast medium. Although the increase in serum creatinine concentration is transient in most cases, contrast-induced AKI may lead to increased morbidity and mortality rates in selected at-risk populations. This review summarizes the findings of a multidisciplinary panel composed of computed tomography radiologists, interventional radiologists, cardiologists, and nephrologists convened to address the specialty-specific issues associated with minimizing the incidence of contrast-induced AKI. As part of this initiative, the panel developed specialty-specific protocols for preventing contrast-induced AKI, taking into account, for example, the variations in patient risk profile, inpatient or outpatient status, and staffing resources that characterize various clinical settings. The 3 protocols, each reflecting a consensus of expert opinion, address the prevention of contrast-induced AKI in interventional radiology, diagnostic computed tomography radiology, and interventional cardiology settings. The protocols are presented in the context of a review of recent guidelines and published reports of trials that discuss contrast-induced AKI and its prevention. © 2009 Mayo Foundation for Medical Education and ResearchA cute kidney injury (AKI) is a heterogeneous disorder with multiple etiologies, risk factors, and clinical presentations. Although patients with AKI are ultimately cared for by nephrologists, AKI occurs in various clinical settings and is associated with a specific etiology in each. The term contrast-induced AKI refers to the disorder as it occurs after exposure to iodinated contrast media, a disorder that has been more commonly known as contrastinduced nephropathy (CIN). The Acute Kidney Injury Network, recognizing the need for improving outcomes associated with the various forms of AKI, recently proposed using the following standardized diagnostic definition in all cases: an abrupt (within 48 hours) reduction in kidney function, evidenced by an increase in the serum creatinine concentration of at least 0.3 mg/dL (to convert to µmol/L, multiply by 88.4) or at least 50% from baseline or a reduction in urine output (documented oliguria of <0.5 mL/kg/h for >6 hours).1,2 The criterion of oliguria does not apply for many cases of contrast-induced AKI because patients are treated with intravenous fluids before and after the procedure with the goal of increasing periprocedural urine output. The most commonly used definition of CIN is an increase from the baseline serum creatinine concentration of at least 0.5 mg/dL or at least 25% within 48 to 72 hours after exposure to contrast media. [3][4][5] Because the medical community is moving to adopt the concept and terminology of the American College of Radiology (ACR) in reference to studies of contrast-induced renal dysfunction and its prevention, 6 this report will do the same. However, we rec...

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“…A more recent nonionic formula requiring one osmotically charged particle to deliver six iodine molecules is more iso-osmolar at 300 mOsm/L. 1,3,9,[11][12][13] The higher the ratio of iodine molecules to particle charges, the better the x-ray image. 5 Osmolality refers to the viscosity or thickness of liquid, and normal blood viscosity is 275 to 300 mOsm/L.…”

Section: Contrast-induced Nephropathymentioning

confidence: 98%

Interventional Procedures: Best Practice to Avoid Complications

Bixby¹

2009

Journal of PeriAnesthesia Nursing

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A double-blind study comparing safety, tolerability and efficacy of iodixanol 320 mgI/ml and ioxaglate 320 mgI/ml in cerebral arteriography

Cited by 30 publications

References 18 publications

Discomfort assessment in peripheral angiography: Randomized clinical trial of Iodixanol 270 versus Ioversol 320 in diabetics with critical limb ischemia

Discomfort assessment in peripheral angiography: Randomized clinical trial of Iodixanol 270 versus Ioversol 320 in diabetics with critical limb ischemia

Contrast-Induced Acute Kidney Injury: Specialty-Specific Protocols for Interventional Radiology, Diagnostic Computed Tomography Radiology, and Interventional Cardiology

Interventional Procedures: Best Practice to Avoid Complications

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