A double‐blind, placebo‐controlled randomized trial evaluating the ability of low‐level laser therapy to improve the appearance of cellulite

Jackson, Robert; Roche, G.; Shanks, Steven

doi:10.1002/lsm.22119

Cited by 42 publications

(32 citation statements)

References 46 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…One of the main proposed mechanism of actions is based upon production of transient pores in adipocytes, allowing lipids to leak out. Another is through activation of the complement cascade which could cause induction of adipocyte apoptosis and subsequent release of lipids [28]. …”

Section: Discussionmentioning

confidence: 99%

Gallium Arsenide Low Level Laser Therapy as an Adjunctive Modality in Treatment of Cellulite After Liposuction

Ibrahim¹,

Borhan²,

Abdelrahman³

et al. 2017

IJPR

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Gallium Arsenide Low Level Laser Therapy as an Adjunctive Modality in Treatment of Cellulite After Liposuction

Ibrahim¹,

Borhan²,

Abdelrahman³

et al. 2017

IJPR

View full text Add to dashboard Cite

“…In regard to different techniques to positively influence cellulite, there is evolving clinical data that for example low level laser therapy (LLLT) with 532 nm wave lengths appears to improve cellulite in a double-blind, placebo-controlled randomized trial [22]. 1064 nm Nd:YAG laser appear to improve mild to moderate cellulite also [23].…”

Section: Combination Therapymentioning

confidence: 99%

Extracorporeal shock wave therapy (ESWT) for the treatment of cellulite – A current metaanalysis

Knobloch¹,

Kraemer²

2015

International Journal of Surgery

View full text Add to dashboard Cite

This metanalysis identified eleven published clinical studies on ESWT in cellulite with five randomized-controlled trials among them. There is growing evidence that both, radial as well as focused ESWT and the combination of both are able to improve the degree of cellulite. Typically, six to eight treatments once or twice a week have been studied. Long-term follow-up data beyond one year are lacking as well as details on potential combination therapies in cellulite such as with low level laser therapy (LLLT), cryolipolysis and others.

show abstract

“…4 The prevalence of cellulite in post-adolescent females was estimated to be between 80% and 90%, 3,5 which led to the development of cosmetic complications. Cellulite appears to be a "multifactorial disorder"…”

Section: Introductionmentioning

confidence: 99%

The Effect of Combination of Red, Infrared and Blue Wavelengths of Low-Level Laser on Reduction of Abdominal Girth: A Before-After Case Series

2017

View full text Add to dashboard Cite

IntroductionThe term cellulite (also known as gynoid lipodystrophy and adiposis edematosa) refers to the herniation of subcutaneous fat within fibrous connective tissue that manifests as skin uneven dimpling or "orange peel" appearance. [1][2][3] Cellulite is more common on the buttocks, lower limbs and abdomen. 1,2 Cellulite affects mainly women as a result of "differences in the structural anatomy of subcutaneous tissue in women, and the possible influence of estrogen. " 4 The prevalence of cellulite in post-adolescent females was estimated to be between 80% and 90%, 3,5 which led to the development of cosmetic complications. Cellulite appears to be a "multifactorial disorder" 4 which is likely due to metabolic alterations, changes in lymphatic and vascular microcirculation, dieting too hard or too much, sex-specific dimorphic, skin architecture, alteration of connective tissue structure, and hormonal and genetic factors. 5-7 Emanuele et al 3 traced "the genetic component of cellulite to particular polymorphisms in the angiotensin converting enzyme (ACE) and hypoxia-inducible factor 1A (HIF1a) genes. " There are various modalities in the treatment of localized subcutaneous fat deposits (massage or mechanical manipulation, mesotherapy, bipolar radiofrequency, liposuction, laser lipolysis, etc), but empirical evidence for the efficacy of these strategies is limited. 3 Low-level laser therapy (LLLT) is a non-thermal, noninvasive technique which is practiced by physicians and laser therapists for a wide variety of diseases. It is used for tissue regeneration and bio-stimulation, pain reduction, swelling, inflammatory response in orthopedic injuries and degenerative diseases, wound healing and numerous Original Article The objective of this study was to assess the efficacy of a combination of 3 wavelengths (including red, infra-red, and blue) of low-level laser (LLL) as a non-invasive therapeutic method to reduce abdominal girth. To achieve biochemical activity on adipocytes, a red laser was used in our selective laser combination. Near-infrared laser was used to increase depth of penetration. Nitrosyl complexes of hemoglobin (NO-Hb) are sensitive to blue light, thereby leading to increase in release of biologically active nitric oxide (NO), which can affect tissue perfusion. Thus, a blue LED was added to the laser combination. Methods: Eighteen females participated in the study. Twelve sessions of laser therapy were performed, 2 sessions per week for each subject. Continuous wave diode lasers, including red (630 nm), infra-red (808 nm), and a blue LED (450 nm) were applied and were all designed by the Canadian Optic and Laser Center. Results: Statistical analyses revealed that upper abdomen size significantly decreased from pre-(91.86 ± 11.16) to post-(87.41 ± 10.52) low-level laser therapy (LLLT) (P < 0.001). Middle abdomen size showed significant reduction from pre-(97.02 ± 8.82) to post-(91.97 ± 8.49) LLLT (P < 0.001). Lower abdomen size significantly decreased from pre-(100.36 ± 9.45) to post-(95.80 ± 8.52) LL...

show abstract

A double‐blind, placebo‐controlled randomized trial evaluating the ability of low‐level laser therapy to improve the appearance of cellulite

Cited by 42 publications

References 46 publications

Gallium Arsenide Low Level Laser Therapy as an Adjunctive Modality in Treatment of Cellulite After Liposuction

Gallium Arsenide Low Level Laser Therapy as an Adjunctive Modality in Treatment of Cellulite After Liposuction

Extracorporeal shock wave therapy (ESWT) for the treatment of cellulite – A current metaanalysis

The Effect of Combination of Red, Infrared and Blue Wavelengths of Low-Level Laser on Reduction of Abdominal Girth: A Before-After Case Series

Contact Info

Product

Resources

About