Abstract:The existence of diurnal rhythm in both protein and carbohydrate metabolisms in different tissues of avian species and mammals has been demonstrated by many researchers1). As to a rhythmic change in lipid metabolism, it has been shown that cholesterol synthesis in the liver2) and intestinal mucosa3) of rats possesses a diurnal rhythm and that this rhythmic change is associated with a change in the activity of 3-hydroxy-3-methylglutaryl-CoA reductase [EC 1. 1. 1. 34], the rate-limiting enzyme for cholesterol sy… Show more
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