A Discrete Swelling of the Upper Lip: A Diagnostic and Clinical Stepladder

Krishnan, Balasubramanian; Basu, Debdatta; Daniel, Jonathan M.

doi:10.1007/s12663-013-0531-6

Cited by 11 publications

(10 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Schwannoma is a benign, asymptomatic, slow-growing, usually solitary tumor that can arise from Schwann cells of the cranial, peripheral, or autonomic nerve sheath [ 3 ]. It was first reported by Verocay in 1908 and was termed neurinoma [ 4 ]. Schwannoma can affect males and females equally in any age group, with a higher incidence in the fourth decade of life [ 5 , 6 ].…”

Section: Discussionmentioning

confidence: 99%

Schwannoma of the Lower Lip: A Case Report of an Unusual Presentation

et al. 2021

View full text Add to dashboard Cite

show abstract

Section: Discussionmentioning

confidence: 99%

Schwannoma of the Lower Lip: A Case Report of an Unusual Presentation

et al. 2021

View full text Add to dashboard Cite

show abstract

“…Patients often delay diagnosis and medical treatment until normal lip function is compromised. Common symptoms include obvious disfigurement, snoring, difficulty with mouth breathing, dysphagia, and dysarthria . Generally, blood and urine chemistries are not necessary and are rarely obtained but are consistently within normal limits.…”

Section: Discussionmentioning

confidence: 99%

“…The majority of reported schwannomas occur in the head and neck regions, ultimately accounting for 25–40% of cases . Although the lips and oral cavity are highly innervated anatomic regions, only 1% of schwannomas originate from peripheral nerves in the intraoral cavity . Schwannoma of the upper and lower lips presents as a painless mass with conventional histology demonstrating Antoni A (Verocay) patterns of nuclear palisades surrounding cellular bodies alternating with hypocellular Antoni B patterns .…”

Section: Introductionmentioning

confidence: 99%

“…Perioral schwannomas commonly produce uncomfortable symptoms such as dysarthria, dysphagia, snoring, impaired mouth breathing, interference with speech and swallowing, and rarely pain and paresthesia . Moreover, schwannomas of the lip also cause obvious aesthetic disfigurement for the patient and often lead to emotional distress . Complete surgical excision typically leads to favorable outcomes without recurrence .…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Clinical features and management of schwannoma affecting the upper and lower lips

et al. 2018

View full text Add to dashboard Cite

Head and neck schwannomas comprise 25-40% of all schwannomas, with presentation on the lips as the rarest and most surgically complicated site for perioral tumors. A systematic literature review was conducted to include 21 cases of patients with schwannoma of the upper or lower lips. The majority of patients presented with a single, painless, well-encapsulated nodule on the upper or lower lips. The nodules were consistently slow-growing, with an average 29.3 months from symptom onset to clinical presentation. Most cases were complicated by profound cosmetic disfigurement as well as dysphagia, dysarthria, snoring, and/or sleep apnea. Overall, histological analysis was consistent with classic schwannoma, and all cases were treated via complete surgical excision, and for malignant tumors, additional therapy was utilized. All but four cases achieved full remission by final follow-up. Recurrence rate for benign lip schwannomas was 5.3%, which is remarkably different from the standard recurrence rate of 8-24% for benign peripheral schwannomas. Additionally, the proportion of malignant tumors was greater for lip schwannomas than other schwannomas. Lip schwannomas demonstrate different characteristics than schwannomas from other locations on the body, and these remarkable differences highlight significant implications for clinical practice. Complete excision is the primary mode of treatment with overall excellent postoperative prognosis and rare instances of recurrence. Given the rarity of this tumor, this review of available cases serves to comprehensively describe clinical presentation and surgical treatment approaches to upper and lower lip schwannomas.

show abstract

“…[8] In spite of the fact that they are common in the head-and-neck region, the involvement of the lip is considered to be extremely rare. [9] Histologically, schwannomas are divided into the following seven subtypes: classical (Verocay), plexiform, cellular, cranial nerve, melanotic, degenerated (ancient), and granular cell schwannomas. [10]…”

Section: Introductionmentioning

confidence: 99%

Lower lip plexiform schwannoma: Report of a rare case and a literature review

Yaghoobi

Pazyar

2019

Indian J Dermatol

View full text Add to dashboard Cite

Plexiform schwannoma is an uncommon benign neoplasm of the neural sheath characterized grossly and microscopically by multinodular growth. It is typically presented as a mobile, solitary, smooth-surfaced, and nontender mass. Histologically, schwannomas are classified into the following seven types: classical (Verocay), plexiform, cellular, cranial nerve, melanotic, degenerated (ancient), and granular cell schwannomas. In spite of the fact that plexiform schwannoma commonly occurs in the head-and-neck region, the involvement of the lip is considered to be extremely rare. Herein, we present the case of a 16-year-old boy with the schwannoma on the lower lip excised without any recurrence at 9 months after surgery.

show abstract

A Discrete Swelling of the Upper Lip: A Diagnostic and Clinical Stepladder

Cited by 11 publications

References 22 publications

Schwannoma of the Lower Lip: A Case Report of an Unusual Presentation

Schwannoma of the Lower Lip: A Case Report of an Unusual Presentation

Clinical features and management of schwannoma affecting the upper and lower lips

Lower lip plexiform schwannoma: Report of a rare case and a literature review

Contact Info

Product

Resources

About