A differential color flicker test for detecting acquired color vision impairment in multiple sclerosis and diabetic retinopathy

Gregori, B.; Papazachariadis, Odysseas; Farruggia, Alfonsa; Accornero, N.

doi:10.1016/j.jns.2010.09.002

Cited by 18 publications

(14 citation statements)

References 39 publications

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“…hMT/V5+ is well known for its importance in the analysis of visual motion processing [25]–[27] but its role in CFFt perception needs further clarification. Additional information on the contribution of different cortical areas to CFFt is needed to better understand the pathophysiological mechanisms of altered temporal processing of visual stimuli reported in several neurological disorders [10], [28]–[34].…”

Section: Introductionmentioning

confidence: 99%

Inferior Parietal Lobule Encodes Visual Temporal Resolution Processes Contributing to the Critical Flicker Frequency Threshold in Humans

et al. 2014

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The measurement of the Critical Flicker Frequency threshold is used to study the visual temporal resolution in healthy subjects and in pathological conditions. To better understand the role played by different cortical areas in the Critical Flicker Frequency threshold perception we used continuous Theta Burst Stimulation (cTBS), an inhibitory plasticity-inducing protocol based on repetitive transcranial magnetic stimulation. The Critical Flicker Frequency threshold was measured in twelve healthy subjects before and after cTBS applied over different cortical areas in separate sessions. cTBS over the left inferior parietal lobule altered the Critical Flicker Frequency threshold, whereas cTBS over the left mediotemporal cortex, primary visual cortex and right inferior parietal lobule left the Critical Flicker Frequency threshold unchanged. No statistical difference was found when the red or blue lights were used. Our findings show that left inferior parietal lobule is causally involved in the conscious perception of Critical Flicker Frequency and that Critical Flicker Frequency threshold can be modulated by plasticity-inducing protocols.

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Section: Introductionmentioning

confidence: 99%

Inferior Parietal Lobule Encodes Visual Temporal Resolution Processes Contributing to the Critical Flicker Frequency Threshold in Humans

et al. 2014

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“…The results showed that the peculiarities of the CFFF reaction really depends from functional state and the method of DHT-FFF can be used to evaluate the effects of changes of human functional state under different light conditions. Although previous researchers have used the measurement of CFFF for different levels of intensity [32,33] and different colors [27], as far as we know, such combination of brightness levels and color of flicker has not been studied in details before. Also looks interesting the parallel changes of CFFF and eye-dominance during development of fatigue.…”

Section: Discussionmentioning

confidence: 99%

“…It is the key parameter of the nervous system, that is largely determine its response to external stimuli [22][23][24]. Critical flicker fusion frequency was used to assess the functional states such as fatigue both in laboratory conditions [25] and in the production [26], for medical targets [27].…”

Section: Lightingmentioning

confidence: 99%

Research perspectives of the influence of lighting modes on changes of human functional state by means of “smart lighting”

Berlov

Baranova

Bisegna

et al. 2015

2015 IEEE 15th International Conference on Environment and Electrical Engineering (EEEIC)

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In studies of non-visual lighting effects conflicting results are frequently obtained. We suppose that such individual differences can be related to the initial functional state, as well as to the individual type of response to light exposure. This raises the question of the need to develop methods for express-diagnosis of functional state in response to a standardized light exposure. Our results show that the effect of fatigue during mental workload can be detected by measuring the critical flicker fusion frequency for light with the specific colors and brightness levels. However, the reliability of this method is difficult to estimate because of the different brightness of LEDs of different colors. We believe that the using of a "smart lighting" devices, allowing obtaining specific color and brightness by mixing individual colored LEDs, will overcome this limitation. Keywords-non-visual effects of light; color flicker fusion frequency; LED; functional states; mental fatigue; smart lighting; physiological labilityI.

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“…A szerzők konklúziója alapján összességében nagyobb mértékű csökkenést írtak le opticusneuritis esetén, mint diabeteses retinopathiában. Általánosságban megállapították azt is, hogy az életkor előrehaladtával a kék szín küszöbe egészségesekben is fokozatosan csökken [5].…”

Section: Megbeszélésunclassified

“…Az eredményt módosító faktor lehet például a megvilágító fény ereje [1], színe [4,5], kitöltési tényező-je [6] (a LED egy periódusra vonatkozó világítás időtar-tama). Továbbá módosul a CFF cataracta [7] vagy maculadegeneráció [4] jelenlétében, alkoholfogyasztás [8] és dohányzás [8] hatására, és nemtől függően [9] is.…”

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Az IMEA ADR III kritikus fúziós frekvenciavizsgáló eszközzel végzett mérések reprodukálhatóságának vizsgálata

et al. 2016

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Bevezetés: A centrális kritikus fúziós frekvencia (CFF) mérése a szemészetben gyakran alkalmazott vizsgálat, segítséget adhat több szemészeti, neurológiai, belgyógyászati betegség diagnosztizálásában, illetve meglévő betegségek progreszsziójának követésében. Célkitűzés: A szerzők az IMEA ADR III digitális CFF-mérő készüléket tesztelték 30 fiatal, egészséges, magyar személyen. Módszer: Általános szemészeti vizsgálatot követően, a műszer által kibocsátott négyféle fénnyel végeztek méréseket, minden színnel ötször egymás után, két különböző napon, három különböző időpont-ban, standardizált körülmények mellett. A statisztikai elemzés során az intrasession-, intersession-és intervisit-variabilitást, az egyes színek közötti különbségeket és egyes befolyásoló faktorok hatásait vizsgálták. Eredmények: Az egyes mérési sorozatok között sem középértékben, sem a szórásokban nem találtak különbséget. A vörös színnel végzett vizsgálat küszöbérték-eredményei statisztikailag alacsonyabbak voltak a többinél, illetve a kék szín küszöbértékei alacsonyabbak voltak a zöldnél. A nemre, életkorra, íriszszínre és dohányzásra vonatkozóan nem találtak különbségeket a küszöbértékekben. Következtetések: A műszer egészséges populáción, egymástól független időpontokban, megbízha-tóan, pontosan mér, az eredmények jól reprodukálhatóak. Orv. Hetil., 2016, 157(27), 1079-1086. Kulcsszavak: kritikus fúziós frekvencia, CFF, reprodukálhatóságReproducibility of measurements using the IMEA ADR III critical flicker-fusion frequency measuring device Introduction: Measurement of central critical flicker-fusion frequency is a common screening test for eye diseases and additionally it can serve as a useful diagnostic test in numerous neurological and internal diseases. The test might also be used for monitoring purposes. Aim: The aim of the authors was to evaluate a digital central critical flicker-fusion frequency measuring device (IMEA ADR III) in 30 young, healthy Hungarian subjects. Method: After a general ophthalmological screening examination, monocular central critical flicker-fusion frequency was measured with four colours. Measurements were carried out on two separate days in three sessions under standardized conditions. Intrasession, intersession and intervisit variabilities, differences in central critical flicker-fusion frequency using the four colours and the effect of certain other influencing factors were determined. Results: There were no statistically significant differences between sessions in the mean and standard deviation of the measurement sets. The central critical flicker-fusion frequency threshold for red colour was significantly lower than for other colours, and the threshold for blue colour was significantly lower than for green. There were no significant differences regarding sex, age, iris colour, and smoking indicating that these factors did not influence the central critical flicker-fusion frequency threshold in these subjects. Conclusions: Measurement results with the device are reliable and reproducible in healthy, young po...

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A differential color flicker test for detecting acquired color vision impairment in multiple sclerosis and diabetic retinopathy

Cited by 18 publications

References 39 publications

Inferior Parietal Lobule Encodes Visual Temporal Resolution Processes Contributing to the Critical Flicker Frequency Threshold in Humans

Inferior Parietal Lobule Encodes Visual Temporal Resolution Processes Contributing to the Critical Flicker Frequency Threshold in Humans

Research perspectives of the influence of lighting modes on changes of human functional state by means of “smart lighting”

Az IMEA ADR III kritikus fúziós frekvenciavizsgáló eszközzel végzett mérések reprodukálhatóságának vizsgálata

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A differential color flicker test for detecting acquired color vision impairment in multiple sclerosis and diabetic retinopathy

Cited by 18 publications

References 39 publications

Inferior Parietal Lobule Encodes Visual Temporal Resolution Processes Contributing to the Critical Flicker Frequency Threshold in Humans

Inferior Parietal Lobule Encodes Visual Temporal Resolution Processes Contributing to the Critical Flicker Frequency Threshold in Humans

Research perspectives of the influence of lighting modes on changes of human functional state by means of &#x201C;smart lighting&#x201D;

Az IMEA ADR III kritikus fúziós frekvenciavizsgáló eszközzel végzett mérések reprodukálhatóságának vizsgálata

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Research perspectives of the influence of lighting modes on changes of human functional state by means of “smart lighting”