A Diet Low in FODMAPs Reduces Symptoms of Irritable Bowel Syndrome

The current treatment landscape of irritable bowel syndrome in adults in Hong Kong: consensus statements

“…17 Cognitive behavioural therapy also showed a significant benefit on the work and social adjustment scale that persisted 12 months after therapy (mean reduction of 2.8 points). 17 19 Involvement of dieticians may improve accuracy and adherence to the low-FODMAP diet or other specific diets. 20 In a randomised, controlled, single-blind, crossover trial, a low-FODMAP (fermentable oligosaccharides, disaccharides, monosaccharides, and polyols) diet for 21 days led to a significant improvement in symptoms of IBS (including abdominal pain, bloating, passage of gas and dissatisfaction with stool consistency) and quality of life compared with a standard Australian diet.…”

“…20 In a randomised, controlled, single-blind, crossover trial, a low-FODMAP (fermentable oligosaccharides, disaccharides, monosaccharides, and polyols) diet for 21 days led to a significant improvement in symptoms of IBS (including abdominal pain, bloating, passage of gas and dissatisfaction with stool consistency) and quality of life compared with a standard Australian diet. 19 Possible mechanisms include a decrease in osmotic diarrhoea, fermentation and altered gut microbiota, immune activation and visceral sensitivity. 21,22 Statement 9: Other dietary concerns that may affect IBS include lactose intolerance, high-fat diet, high-fibre diet, chilli, and gluten.…”

481 Individualized Responses of Gut Microbiota to Dietary Intervention Modeled in Humanized Mice

“…Such strategies have been used as a common intervention (7), and yet the response rates are highly variable, suggesting that interindividual microbiota differences may contribute to this variability. Recent studies in humans highlight the interindividual responses of microbiota composition following specific dietary interventions (1,(8)(9)(10)(11); however, the interpretation of the data is limited by a lack of biological replicates for each microbiota composition.…”

Effect of a prebiotic galactooligosaccharide mixture (B‐GOS®) on gastrointestinal symptoms in adults selected from a general population who suffer with bloating, abdominal pain, or flatulence

“…8 However, this strategy may be criticized for its negative effects on GI environment, in terms of metabolism 9,10 and altered composition of GI microbiota. [11][12][13] Almost without exception, all FODMAPS contain fructose and the symptom induction after ingestion of these substrates is well documented in both uncontrolled 14,15 and controlled 16,17 trials. Similarly, prebiotics such as inulin and FOS also contain fructose and, regardless of their positive effect upon GI environment, have been shown to either result in side effects such as increased bloating, flatulence, or abdominal pain or to have no impact on these GI symptoms in healthy adults and those with IBS.…”