The current treatment landscape of irritable bowel syndrome in adults in Hong Kong: consensus statements

Wu, Justin C.Y.; Chan, Annie Oo; Chan, Y.; Cheung, TK; Kwan, Alan Shu Khen; Leung, Vincent; Mak, Amanda Nga-Sze; Sze, Stephen Cho Wing; Wong, Reuben K.

doi:10.12809/hkmj177060

Cited by 11 publications

(16 citation statements)

References 26 publications

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“…Fifth, we did not adopt the Rome IV criteria for IBS . Although Rome IV may be more specific in its requirement for abdominal pain instead of “abdominal discomfort” as a diagnostic criterion, the specific cultural connotation of admitting to having “pain” in Chinese has been suggested to lead to a tendency to describe pain in different terms, such as abdominal bloating or discomfort, in which case the Rome III criteria may remain appropriate in the Chinese context . Sixth, we did not intentionally exclude patients below any particular BMI cut‐off.…”

Section: Limitationsmentioning

confidence: 99%

“…56 Although Rome IV may be more specific in its requirement for abdominal pain instead of "abdominal discomfort" as a diagnostic criterion, the specific cultural connotation of admitting to having "pain" in Chinese 57 has been suggested to lead to a tendency to describe pain in different terms, such as abdominal bloating or discomfort, in which case the Rome III criteria may remain appropriate in the Chinese context. 58 Sixth, we did not intentionally exclude patients below any particular BMI cutoff. Although no subjects in the resultant sample suffered from any eating disorder, it would be important to exclude patients with eating disorders to allow a more specific examination of cognitive function in IBS, as disordered eating is commonly seen in patients with functional gastrointestinal disorders and is associated with cognitive impairment.…”

Section: M Itati O N Smentioning

confidence: 99%

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Nature and specificity of altered cognitive functioning in IBS

Wong

Mak

Yuen

et al. 2019

Neurogastroenterology Motil

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Background It is unknown whether cognitive dysfunction found in patients with irritable bowel syndrome (IBS) was attributable to the different subtypes, ongoing pathophysiological processes, trait characteristics, or psychiatric comorbidity. Methods Forty Rome‐III patients with IBS (20 diarrhea‐predominant [IBS‐D] and 20 constipation‐predominant [IBS‐C]) and 40 age‐, sex‐, education‐matched healthy controls were systematically recruited and compared on their cognitive function with continuous performance test (CPT), Wisconsin Card Sorting Test (WCST) and emotional Stroop test. Beck Anxiety Inventory (BAI), Beck Depression Inventory‐II (BDI‐II), Patient Health Questionnaire‐15 (PHQ‐15) and a structured bowel symptom questionnaire were performed to measure anxiety, depressive, somatization, and bowel symptoms, respectively. Psychiatric diagnoses were ascertained with SCID‐I (Structured Clinical Interview for DSM‐IV Axis I Disorders). Key Results Patients with IBS showed significantly increased standard deviation of reaction time (SDRT) (P = .003) on CPT, increased failure to maintain set (FMS) (P=.002), and percentage of perseverative errors (P = .003) on WCST. SDRT did not correlate with illness chronicity or bowel symptoms. FMS correlated with bowel symptom severity. In logistic regression models controlled for BAI, BDI‐II, and PHQ‐15, SDRT (AOR = 1.08, P = .025), but not FMS (P = .25) or percentage of perseverative errors (P = .24), significantly differentiated IBS from controls. Cognitive function was not significantly different between IBS‐C and IBS‐D (P > .05), or between pure IBS (n = 22) and IBS with generalized anxiety disorder (GAD) (n = 17) (P > .05). Conclusions & Inferences Patients with IBS showed attentional and executive function impairment irrespective of subtypes but otherwise heterogeneous in terms of its state‐trait correlations and overlap with anxiety comorbidity.

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Section: Limitationsmentioning

confidence: 99%

Section: M Itati O N Smentioning

confidence: 99%

Nature and specificity of altered cognitive functioning in IBS

Wong

Mak

Yuen

et al. 2019

Neurogastroenterology Motil

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“…A total of 994 records were retrieved; 31 records were considered potentially eligible for full-text screening, and 7 guidelines proved eligible [24][25][26][27][28][29][30] (Fig. 1).…”

Section: Resultsmentioning

confidence: 99%

“…1). Eligible guidelines included 1 global guideline [30] and 6 national guidelines [24][25][26][27][28][29]. Guidelines were published from 2014 to 2018 by the following agencies: American College of Gastroenterology (ACG), the American Gastroenterological Association (AGA), Korean Society of Neurogastroenterology and Motility (KSNM), the Japanese Society of Gastroenterology (JSGE), National Institute for Health and Care Excellence (NICE), the Hong Kong Advisory Council on IBS (HKAC) and World Gastroenterology Organisation (WGO; Table 1).…”

Section: Resultsmentioning

confidence: 99%

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Assessment of the Quality and Content of Clinical Practice Guidelines on Irritable Bowel Syndrome Using the AGREE II Instrument

Xing

Yao

et al. 2019

Digestion

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Objectives: The aim of the study was to assess the quality of guidelines on irritable bowel syndrome (IBS) using the Appraisal of Guidelines for Research and Evaluation II (AGREE II) instrument and identify concordance of different commendations. Materials and Methods: A systematic search was undertaken from inception to May 2018. Two reviewers independently selected the titles and abstracts. The guidelines included were assessed using the AGREE II instrument. The consistency of evaluations was calculated using intra-class correlation coefficients with 95% CI. Results: From 994 records, 7 guidelines were included. Most of guidelines got a moderate score of AGREE II. The highest median scores were achieved for scope and purpose and clarity and presentation (69.4%), while the lowest median scores across guidelines were for applicability (50.0%). Most of the nonpharmacologic management recommendations for IBS were similar. However, there also existed some differences on pharmacologic between different guidelines. Conclusions: The guidelines on IBS varied in quality and there were discrepancies about recommendations and recommendation grades. There is some space to improvement the quality of methodological rigor in development and reporting within clinical guidelines.

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