A Demographic and Clinical Panorama of a Sixteen-Year Cohort of Soft Tissue Sarcoma Patients in Brazil

Abstract

Introduction: Little is known about soft tissue sarcomas (STS) in Brazil, once the federal statistics regarding estimates on incidence and mortality of the most common cancers that affect the Brazilian population currently do not include STS. This study aims to perform a broad evaluation and description of the epidemiological profile, access to treatment and main clinical outcomes of the Brazilian STS patient.Methods: A population-based cohort study of 66,825 patients who underwent procedures related to STS treatment registered in the Brazilian public health system (Sistema Único de Saúde, SUS) databases. Results: Median age was 57 years, 30% of them older than 65 years and 50.7% of the cohort was female. The majority, 50,383 patients (75.4%), was diagnosed between 2008 and 2015. Most prevalent anatomic sites were head and neck (13.6%) and upper and lower limbs (12.6%). The registry of sarcomas without a specific location comprehended 29.7% of the cohort. The majority of patients resided in the Northeast (40.2% of the patients). Surgery was the first treatment modality in 77.7% of the cases. The 1-, 5- and 10-year survival rate of the patients was, respectively, 82.3% (95% CI = 82%-82,7%), 57.4% (95% CI = 56.9%-58%) and 42% (95% CI = 41.2%-42.9%).

Soft-Tissue Sarcomas in Adults in Ecuador in the Period 2010–2020

“…Te data reported in several studies do not show a gender distribution; however, our results show an almost uniform distribution between genders, with a slight majority of patients being male (50.61%) and living in the highlands, results that are similar to those published by Bozzo et al in Canada [11] in a fve-year cohort study. However, these data are in contrast with those reported in Brazil in a sixteen-year cohort study where soft-tissue sarcomas were reported to be slightly higher in females [12]. Te results of this study in this sense resemble those of a ten-year retrospective cohort study in Germany that reported an even distribution between genders [13].…”