A decade of silicone hydrogel development: how has clinical experience informed material design?

The TFOS International Workshop on Contact Lens Discomfort: Report of the Contact Lens Materials, Design, and Care Subcommittee

“…1 Silicone hydrogel development typically focused on compositions or macromers based on silicone-containing monomers (TRIS, siloxy macromer) that are sufficiently compatible with a range of hydrophilic monomers (including N,N-dimethyl acrylamide, NVP, polyHEMA). 4,[20][21][22][23][24][25][26][27][28][29] Although the siloxane groups confer high oxygen permeability, they also give rise to inherent wettability issues, so several strategies have been employed to render SiHy surfaces more hydrophilic. Appendix B provides an overview of the characteristics of some SiHy materials.…”