A Decade of Living Lobar Lung Transplantation: Perioperative Complications after 253 Donor Lobectomies

Bowdish, Michael E.; Barr, Mark L.; Schenkel, Felicia A.; Woo, Marlyn S.; Bremner, Ross M.; Horn, Monica V.; Baker, Craig J.; Barbers, Richard G.; Wells, Winfield J.; Starnes, Vaughn A.

doi:10.1111/j.1600-6143.2004.00514.x

Cited by 62 publications

(47 citation statements)

References 25 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Sabe-se que uma lobectomia pulmonar, mesmo em pacientes sadios, não é desprovida de riscos. Na avaliação de 253 doadores, Bowdish et al obtiveram 19,8% de morbidade com nenhum óbito 10 . Em recente publicação, nosso grupo reportou as complicações com 32 doadores, com 31,25% de morbidade e zero de mortalidade 11 .…”

Section: Discussionunclassified

Twelve-year survival of the first living-donor pediatric lung transplantation in Brazil

Machuca¹,

Filho²,

Schio³

et al. 2012

J Pediatr (Rio J)

View full text Add to dashboard Cite

Objective: To report the long-term follow-up of the first living-donor lobar lung transplantation performed in Latin America. Description:The patient was a 12-year-old boy with post-infectious obliterative bronchiolitis with end-stage pulmonary disease. He was on continuous oxygen support, presenting with dyspnea even during minimal activity. He underwent bilateral lobar lung transplantation with living donors. The procedure was performed with the left and right lower lobes of two different related donors. In the second side cardiopulmonary bypass was required. The transplant was uneventful, and the patient was extubated after 14 hours and discharged with 44 days, after resolution of infectious, immunological and drug-related complications. After 12 years of follow-up, he presents with adequate lung function and has resumed his habitual activities.Comments: Living-donor lobar lung transplantation is a complex procedure feasible for the treatment of selected pediatric end-stage pulmonary disease. This particular population might benefit from this approach since the availability of pediatric donors is very scarce and the clinical course of pediatric advanced pulmonary disease may be unpredictable.J Pediatr (Rio J). 2012;88(5):413-6: Lung transplantation, bronchiolitis obliterans, living donors, pediatrics. ResumoObjetivo: Apresentar o acompanhamento a longo prazo do primeiro caso de transplante pulmonar intervivos realizado na América Latina.Descrição: Paciente do sexo masculino, com 12 anos de idade, portador de bronquiolite obliterante com doença pulmonar avançada. Fazia uso de oxigênio domiciliar contínuo, com dispneia aos mínimos esforços. Foi submetido a transplante pulmonar bilateral com doadores vivos. A cirurgia foi realizada utilizando os lobos inferiores esquerdo e direito de dois doadores diferentes e com grau de parentesco com o receptor. No segundo lado (direito), foi necessário emprego de circulação extracorpórea. O transplante não teve intercorrências, e o paciente foi extubado com 14 horas de pós-operatório; com 44 dias, recebeu alta hospitalar, após a resolução de complicações infecciosas, imunológicas e medicamentosas. Após 12 anos de seguimento, encontra-se com função pulmonar preservada e desempenha normalmente suas atividades.Comentários: O transplante pulmonar intervivos é um procedimento de alta complexidade que pode contribuir para o tratamento de algumas pneumopatias na infância. Essa população se beneficia dessa abordagem, uma vez que a disponibilidade de doadores pediátricos é muito rara, e as pneumopatias pediátricas tendem a seguir um curso imprevisível. J Pediatr (Rio J)

show abstract

Section: Discussionunclassified

Twelve-year survival of the first living-donor pediatric lung transplantation in Brazil

Machuca¹,

Filho²,

Schio³

et al. 2012

J Pediatr (Rio J)

View full text Add to dashboard Cite

show abstract

“…According to previous reports, no perioperative death has been reported although relatively high morbidity after lobectomy has been described (29,30). Morbidity rates ranged from 20% to 60%.…”

Section: Perioperative Complications In Living Donorsmentioning

confidence: 99%

Living Related Lung Transplantation

Date

2014

Regenerative Medicine Applications in Organ Transplantation

View full text Add to dashboard Cite

“…Although several studies, including the recently published largest series from 2 large centers in the United States, have described the pre-operative and post-operative characteristics and assessed the outcomes of living lobar lung donors, 1,2,[4][5][6][7][8] there are insufficient updated and recent studies on LDLLT. This study comprehensively evaluated the outcomes of donor lobectomies in recent years by reviewing pre-operative characteristics, intraoperative findings, post-operative complications, and post-operative pulmonary function.…”

mentioning

confidence: 99%