A cross sectional observational study on the influence of chronic obstructive pulmonary disease on activities of daily living: the COPD-Life study

Polatlı, Mehmet; Bilgin, Cahit; Şaylan, Bengü; Başlılar, Şeyma; Toprak, Emine Kilic; Ergen, Halil Ibrahim; Nd, Bakan; Kart, Levent; Kılıç, Zübeyir; Üstünel, A; Şengün, A; Varol, Yelda; Yılmaz, Adnan; Ataol, Ç; Bulgur, D; S, Bozdoğan; Tunaboyu, I; Zg, Özkan; Uysal, Erdem; Gülgösteren, S; Akın, N; Selim, Yasmeen M M; Irmak, Mustafa Yasin; Turgut, Ezgi; Keskin, Özlem; H, Bektaş Uysal; Sofuoğlu, N; Yilmaz, Mehmet

doi:10.5578/tt.3414

Cited by 19 publications

(23 citation statements)

References 43 publications

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“…Two other reports corroborated that the more severe the dyspnoea symptom, the lower utility patients place on their health, though the specific levels of breathlessness were described differently (table 3) [43,49]. Other structured surveys, without reporting utility values, also suggested dyspnoea as burdensome and a very important consideration in COPD-related decision-making [31,[50][51][52][53][54][55][56][57][58]. Table 4 summarises the results related to the importance of adverse events.…”

Section: /3 +++− Moderate Certainty Due To Risk Of Bias ¶ ¶mentioning

confidence: 79%

A systematic review of how patients value COPD outcomes

et al. 2018

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Our objective was to summarise systematically all research evidence related to how patients value outcomes in chronic obstructive pulmonary disease (COPD).We conducted a systematic review (systematic review registration number CRD42015015206) by searching PubMed, Embase, PsycInfo and CINAHL, and included reports that assessed the relative importance of outcomes from COPD patients' perspective. Two authors independently determined the eligibility of studies, abstracted the eligible studies and assessed risk of bias. We narratively summarised eligible studies, meta-analysed utilities for individual outcomes and assessed the certainty of evidence using the Grading of Recommendations, Assessment, Development and Evaluations approach.We included 217 quantitative studies. Investigators most commonly used utility measurements of outcomes (n=136), discrete choice exercises (n=13), probability trade-off (n=4) and forced choice techniques (n=46). Patients rated adverse events as important but on average, less so than symptom relief. Exacerbation and hospitalisation due to exacerbation are the outcomes that COPD patients rate as most important. This systematic review provides a comprehensive registry of related studies.

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Section: /3 +++− Moderate Certainty Due To Risk Of Bias ¶ ¶mentioning

confidence: 79%

A systematic review of how patients value COPD outcomes

et al. 2018

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“…10 In this respect, a recent study performed in Turkey in 497 stable COPD patients suggested that reducing breathlessness was more of an incentive to seeking treatment than was controlling productive cough. 33 It has been reported in the literature that COPD drives more healthcare consumption than many other chronic diseases. For example, in the United Kingdom, it was reported that the number of physician consultations for respiratory diseases is over three times as high as that for diseases of the circulatory or digestive system.…”

Section: Discussionmentioning

confidence: 99%

Chronic obstructive pulmonary disease and associated healthcare resource consumption in the Middle East and North Africa: The BREATHE study

Polatlı

Kheder

Wali

et al. 2012

Respiratory Medicine

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Data on COPD-related healthcare resources use are rarely documented in developing countries. This article presents data on COPD-related healthcare resource consumption in the Middle East, North Africa and Pakistan and addresses the association of this variable with illness severity. A large survey of COPD was conducted in eleven countries of the region, namely Algeria, Egypt, Jordan, Lebanon, Morocco, Pakistan, Saudi-Arabia, Syria, Tunisia, Turkey and United Arab Emirates, using a standardised methodology. A total of 62,086 subjects were screened. This identified 2,187 subjects fulfilling the "epidemiological" definition of COPD. A detailed questionnaire was administered to document data on COPD-related healthcare consumption. Symptom severity was assessed using the COPD Assessment Test (CAT). 1,392 subjects were analysable. Physician consultations were the most frequently used healthcare resource, ranging from 43,118 [95% CI: 755-85,548] consultations in UAE to 4,276,800 [95% CI: 2,320,164-6,230,763] in Pakistan, followed by emergency room visits, ranging from 15,917 [95% CI: 0-34,807] visits in UAE to 683,697 [95% CI: 496,993-869,737] in Turkey and hospitalisations, ranging from 15,563 [95% CI: 7,911-23,215] in UAE to 476,674 [95% CI: 301,258-652,090] in Turkey. The use of each resource increased proportionally with the GOLD 2011 severity groups and was significantly (p < 0.0001) higher in subjects with more symptoms compared to those with lower symptoms and in subjects with exacerbations to those without exacerbations. The occurrence of exacerbations and the CAT score were independently associated with use of each healthcare resource. In conclusion, the BREATHE study revealed that physician consultation is the most frequently COPD-related healthcare resource used in the region. It showed that the deterioration of COPD symptoms and the frequency of exacerbations raised healthcare resource consumption.

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“…A Turkish, national, observational study of 497 COPD patients found that two-thirds of patients knew their diagnosis, 80% knew they required lifelong treatment, 80% experienced respiratory symptoms, and 90% reduced their daily activities due to dyspnea. 39 A study by Miravitlles and others found that only 27% of patients with airflow limitation identified by spirometry had previously been diagnosed with COPD. 40 Those with a diagnosis of COPD had more severe disease and greater impairment in HRQL and activities of daily living (ADL).…”

Section: Discussionmentioning

confidence: 99%

Therapeutic paralysis in Veterans with COPD

Mulhall

Lach

Krzywkowski-Mohn

et al. 2013

Respiratory Medicine

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Summary Background Chronic Obstructive Pulmonary Disease (COPD) is a common disorder of Veterans that causes significant morbidity and mortality. To measure Veterans’ perceptions about COPD, the effect of COPD on their lives and health, and their needs for improved health, we performed a postal survey. Methods 3263 Veterans with a diagnosis of COPD who received care at the Cincinnati Veterans Affairs Medical Center in 2008 were stratified into quintiles by Veterans Health Administration - associated COPD healthcare cost and uniformly sampled. Results 493 of 1000 surveys (49%) were completed and returned. COPD had different effects on respondents in top and bottom quintiles (highest and lowest COPD-related cost) for: knowledge of COPD diagnosis (89% vs 73%, p=0.03); activities affected by breathing, including work (69% vs 45%), recreation (85% vs 62%), change in living arrangements (36% vs 16%), and increased need for help (54% vs 25%) (p<0.05 for all comparisons); emotional effect of respiratory symptoms, including depression (53% vs 30%), fear (41% vs 15%), and helplessness (49% vs 24%) (p<0.05 for all comparisons). 91% of Veterans were prescribed inhalers and one quarter had difficulties using them. 25% of Veterans did nothing when they had symptoms of an exacerbation. Conclusions COPD has profound effects on Veterans’ breathing related activities and generates many negative emotions. Primary care providers are critical in conveying the diagnosis of COPD and providing information about the disease and its management. Veterans with COPD adhere poorly to their medications, and report little instruction about COPD or its management.

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A cross sectional observational study on the influence of chronic obstructive pulmonary disease on activities of daily living: the COPD-Life study

Cited by 19 publications

References 43 publications

A systematic review of how patients value COPD outcomes

A systematic review of how patients value COPD outcomes

Chronic obstructive pulmonary disease and associated healthcare resource consumption in the Middle East and North Africa: The BREATHE study

Therapeutic paralysis in Veterans with COPD

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