Chronic obstructive pulmonary disease and associated healthcare resource consumption in the Middle East and North Africa: The BREATHE study

Polatlı, Mehmet; Kheder, A. Ben; Wali, Siraj O.; Javed, Arshad; Khattab, A.; Mahboub, Bassam; Iraqi, G.; Nejjari, Chakib; Taright, S.; Koniski, Marie-Louise; Rashid, Nauman; Hasnaoui, Abdelkader El

doi:10.1016/s0954-6111(12)70016-1

Cited by 39 publications

(48 citation statements)

References 24 publications

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“…The number of physician consultations was associated with total CAT scores in one study (p,0.001) [34], but not in the others [15,39]. The number of hospitalisations was directly associated with total CAT scores, irrespective of using the total CAT score (p,0.001) [15] or arbitrarily dichotomising the CAT score (e.g.…”

Section: Validitymentioning

confidence: 94%

“…Three studies measured concurrent validity by comparing the total CAT score to healthcare utilisation [15,34,39]. The number of physician consultations was associated with total CAT scores in one study (p,0.001) [34], but not in the others [15,39].…”

Section: Validitymentioning

confidence: 99%

“…The number of hospitalisations was directly associated with total CAT scores, irrespective of using the total CAT score (p,0.001) [15] or arbitrarily dichotomising the CAT score (e.g. ,10 and o10) (p,0.001 [34] and p,0.032 [39] : reported population characteristics for face-to-face questionnaire group only, where the CAT was completed in a face-to-face interview.…”

Section: Validitymentioning

confidence: 99%

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The COPD assessment test: a systematic review

et al. 2014

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The COPD assessment test (CAT) is a self-administered questionnaire that measures healthrelated quality of life. We aimed to systematically evaluate the literature for reliability, validity, responsiveness and minimum clinically important difference (MCID) of the CAT.Multiple databases were searched for studies analysing the psychometric properties of the CAT in adults with chronic obstructive pulmonary disease. Two reviewers independently screened, selected and extracted data, and assessed methodological quality of relevant studies using the COSMIN checklist.From 792 records identified, 36 studies were included. The number of participants ranged from 45 to 6469, mean age from 56 to 73 years, and mean forced expiratory volume in 1 s from 39% to 98% predicted. Internal consistency (reliability) was 0.85-0.98, and test-retest reliability was 0.80-0.96. Convergent and longitudinal validity using Pearson's correlation coefficient were: SGRQ-C 0.69-0.82 and 0.63, CCQ 0.68-0.78 and 0.60, and mMRC 0.29-0.61 and 0.20, respectively. Scores differed with GOLD stages, exacerbation and mMRC grades. Mean scores decreased with pulmonary rehabilitation (2.2-3 units) and increased at exacerbation onset (4.7 units). Only one study with adequate methodology reported an MCID of 2 units and 3.3-3.8 units using the anchor-based approach and distribution-based approach, respectively. Most studies had fair methodological quality.We conclude that the studies support the reliability and validity of the CAT and that the tool is responsive to interventions, although the MCID remains debatable. @ERSpublications Studies support the reliability, validity and responsiveness of the CAT as a HRQoL tool but its MCID remains unclear

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Section: Validitymentioning

confidence: 94%

Section: Validitymentioning

confidence: 99%

Section: Validitymentioning

confidence: 99%

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The COPD assessment test: a systematic review

et al. 2014

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“…Symptomatic COPD was associated with high economic burden across all countries studied in these two surveys [37,38]. Patients in the US also reported the maximum specialist visits, with a mean of 1.8 visits per patient in the past year [39].…”

Section: Resource Use and Direct Costsmentioning

confidence: 96%

Systematic Review of Humanistic and Economic Burden of Symptomatic Chronic Obstructive Pulmonary Disease

Srivastava¹,

Thakur²,

Sharma³

et al. 2015

PharmacoEconomics

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“…Around 50% of pts were using bronchodilators without corticosteroids, long acting bronchodilators. 56 This Data and other studies from Tageldin et al 57 showed that after extrapolation of Data from national population census national healthcare resource consumption due to COPD. Total population of 4,106,427 with population more than 40 yrs of age being 837,711, considering the prevalence of COPD 1.9%.…”

Section: Current Status Of Copd In Uaementioning

confidence: 52%

Chronic Obstructive Pulmonary Disease in Middle East and UAE: An Unrecognized Underestimated Epidemic

Vats¹

2016

JLPRR

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Abbreviations: COPD, chronic obstructive pulmonary disease; GOLD, global initiative for chronic obstructive lung disease; α1-AT, αlpha1-antitrypsin deficiency; CAT, COPD assessment test IntroductionChronic Obstructive Pulmonary Disease (COPD) is defined by the Global initiative for chronic Obstructive Lung Disease (GOLD) as "a common preventable and treatable disease characterized by persistent airflow limitation that is usually progressive and associated with an enhanced chronic inflammatory response in the airways and the lung to noxious particles or gases". 1COPD is a leading cause of morbidity and mortality worldwide. In 2001, the Global Burden of Disease project identified COPD as the sixth leading cause of mortality in middle-or low income countries accounting for 4.9% of total deaths. 2 According to the latest WHO estimates (2004), currently 64million people have COPD and 3million people died of COPD 3 WHO predicts that COPD will become the third leading cause of death worldwide by 2030.Another study in USA, identified COPD as the fourth leading cause of chronic morbidity and mortality 4 and continue to rise steadily, Although around 90% of deaths due to COPD occur in low-or middleincome countries, scarce data are available in these countries on the prevalence of COPD .Although COPD is not a curable disease, elimination or reduction of risk factors can prevent the development or slow down the progression of the disease. The main risk factors for the development of COPD are cigarette smoking, exposure to air pollutants resulting from the burning of wood or other biomass fuels, tuberculosis, occupational exposures and increasing age. 5 The increase in prevalence of COPD is directly related to the increase in prevalence of smoking worldwide, particularly among women and adolescents.Purpose of this review article is to present the current status of smoking and prevalence of COPD and its consequences in UAE along with comparison with GCC countries. Discussion Tobacco smokingA global pandemic: Smoking is a major risk factor for development of COPD than other types of tobacco, and may be predictive of COPD morbidity and mortality with all the adverse consequences.As per WHO (2008) tobacco caused one in ten deaths in adults worldwide, corresponding to a total of fivemillion deaths per year. 6In 2000, the estimated rate of mortality attributable to smoking in the adult population (aged >30years) was 19% in industrialized countries and 9% in developing countries. 7 Moreover, it has been estimated that the tobacco epidemic may kill one in six adults corresponding to 10million people annually in the next 20-30years, with 70-80% of these deaths occurring in developing countries. primarily focus on cigarettes, many people in developing regions smoke tobacco using water-pipes 9 which also increases the risk of COPD, lung cancer & other respiratory problems.10 The nicotine exposure from daily water-pipe use was estimated to be equivalent to smoking 20 cigarettes/day 11 and water pipe smokers report features of depe...

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Chronic obstructive pulmonary disease and associated healthcare resource consumption in the Middle East and North Africa: The BREATHE study

Cited by 39 publications

References 24 publications

The COPD assessment test: a systematic review

The COPD assessment test: a systematic review

Systematic Review of Humanistic and Economic Burden of Symptomatic Chronic Obstructive Pulmonary Disease

Chronic Obstructive Pulmonary Disease in Middle East and UAE: An Unrecognized Underestimated Epidemic

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