A critical review of process parameters influencing the fate of antibiotic resistance genes in the anaerobic digestion of organic waste

Haffiez, Nervana; Chung, Tae Hyun; Zakaria, Basem S.; Shahidi, Manjila; Mezbahuddin, Symon; Hai, Faisal I.; Dhar, Bipro Ranjan

doi:10.1016/j.biortech.2022.127189

Cited by 32 publications

(12 citation statements)

References 127 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…This was achieved at optimum conditions of pH (6) and OLR (2 kgCODm −3 ·days −1 ), and an antibiotic concentration of 75%. The result obtained is in agreement with Conde-Cid et al [ 23 ], Rodríguez-López et al [ 12 ], and Haffiez et al [ 5 ] who reported pH as one of the most important parameters for maximizing the efficiency of pollutants from aqueous solutions. Thus pH affects the biodegradation process via the rate of the chemical reactions and generation of radicals in the process [ 5 ].…”

Section: Discussionsupporting

confidence: 91%

“…The result obtained is in agreement with Conde-Cid et al [ 23 ], Rodríguez-López et al [ 12 ], and Haffiez et al [ 5 ] who reported pH as one of the most important parameters for maximizing the efficiency of pollutants from aqueous solutions. Thus pH affects the biodegradation process via the rate of the chemical reactions and generation of radicals in the process [ 5 ]. A confirmatory experiment was carried out under the optimum conditions and a desirability performance of 85% removal of the contaminant was achieved.…”

Section: Discussionsupporting

confidence: 91%

“…Studies on antibiotics have drawn much attention due to the high detection frequency of antibiotics in the environment [ 1 , 3 , 4 , 5 ]. The detection of antibiotics in the environment is found to be in the range of ng/L and µg/L, and even mg/L [ 6 , 7 ].…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Evaluating the Biodegradation of Veterinary Antibiotics Using Kinetics Model and Response Surface Methodology

et al. 2022

View full text Add to dashboard Cite

The inappropriate use and indiscriminate disposal of antibiotics has become a menace worldwide. The incomplete removal of these contaminants from wastewater treatment plants has also contributed to this. This study presents the biodegradation of two veterinary antibiotics; ciprofloxacin (CIP) and enrofloxacin (ENRO). Kinetics models were explored to understand the dynamics of biodegradation in an anaerobic digestion process. This was carried out in batch reactors under various operating conditions: pH, organic loading rate (OLR), and antibiotic concentration. The influence of the parameters was investigated using a response surface methodology (RSM) based on the Box–Behnken experimental design of 15 runs. The data obtained were fitted on a polynomial function model. OLR and pH exhibited a synergistic and antagonistic effect in the response models developed, with a high correlation regression coefficient (R2; 0.9834–0.9875) close to 1 at a 95% confidence level. The optimum conditions obtained from the RSM numerical optimization were pH (6), OLR (2 kgCOD·m−3·days−1), and an antibiotic concentration of 75%, which gave the removal of CIP, ENRO, and COD, respectively, as 80%, 83%, and 73% at a desirability function of 85%. The kinetics study shows that the biodegradation of antibiotics was well fitted on a first-order model (R2; 0.9885–0.9978) with rate constants ranging from 0.0695 to 0.96 days−1.

show abstract

Section: Discussionsupporting

confidence: 91%

Section: Discussionsupporting

confidence: 91%

See 1 more Smart Citation

Evaluating the Biodegradation of Veterinary Antibiotics Using Kinetics Model and Response Surface Methodology

et al. 2022

View full text Add to dashboard Cite

show abstract

“…Other factors that may contribute to ARGs propagation include the presence of heavy metals, exposure to MPs/NPs, and the use of conductive additives. 18 In this study, the targeted ARGs including tetW, tetA, tetB, tetM, sul1, sul2, bla TEM , ermB, and MGEs (intl1 and intl2) were detected in the digestate (Figure 4a−d). Among all ARGs, sul1 (14−48%) and intl1 (17−43%), followed by tetW (14−26%), were the most abundant in all samples.…”

Section: ■ Materials and Methodsmentioning

confidence: 53%

“…1 Thereby, exposure to NPs can intensify the selective pressure for ARGs proliferation. 18 For instance, Shi et al found that exposure to NPs increased the prevalence of those bacteria, which were potential ARG hosts. 43 Further, the increased ROS production after exposure to NPs could damage the bacterial cell and increase their membrane permeability, potentially causing more bacteria to become ARG receptors via the intrabacterial community transfer of MGEs.…”

Section: ■ Materials and Methodsmentioning

confidence: 99%

Sludge Thermal Hydrolysis for Mitigating Oxidative Stress of Polystyrene Nanoplastics in Anaerobic Digestion: Significance of the Solids Content

Azizi

Zakaria

Haffiez

et al. 2023

ACS Sustainable Chem. Eng.

Self Cite

View full text Add to dashboard Cite

Microplastics and nanoplastics (MPs/NPs) have been extensively detected in sewage sludge. They inevitably transfer to anaerobic digestion (AD) used for sludge processing and induce oxidative stress on the anaerobic microbiome. The thermal hydrolysis process (THP) is a widely implemented sludge pretreatment process to boost methane generation and solids reduction in AD. Although few recent reports indicated that the THP could alleviate oxidative stress of MPs/NPs in AD, little is known about how different solids contents of sludge would influence its effectiveness. This study scrutinized how the THP (160 °C, 60 min) affects AD of primary sludge with 4, 8, and 12% total solids (TS) when exposed to polystyrene nanoplastics (PsNPs). The presence of PsNPs (150 μg/L) substantially enhanced reactive oxygen species (ROS) levels at lower TS (4 and 8%) compared to a higher TS of 12% (16.20–16.71% vs 8.79%). Consequently, methane production decreased by 7.25–15.07% for 4–8% TS. Nonetheless, applying the THP could effectively mitigate ROS-induced stress and the propagation of most antibiotic resistance genes (ARGs). Moreover, a positive correlation was observed between the changes in extracellular polymeric substances due to the THP and the impact of PsNPs. These results provide new insights into understanding the significance of the sludge solids content in the THP for coremediation of PsNPs-induced oxidative stress and ARGs propagation in AD.

show abstract

Effect of veterinary antibiotics on methane yield from livestock manure anaerobic digestion: an analytical review of the evidence

Saady,

Sivaraman,

Venkatachalam

et al. 2024

Rev Environ Sci Biotechnol

View full text Add to dashboard Cite

A critical review of process parameters influencing the fate of antibiotic resistance genes in the anaerobic digestion of organic waste

Cited by 32 publications

References 127 publications

Evaluating the Biodegradation of Veterinary Antibiotics Using Kinetics Model and Response Surface Methodology

Evaluating the Biodegradation of Veterinary Antibiotics Using Kinetics Model and Response Surface Methodology

Sludge Thermal Hydrolysis for Mitigating Oxidative Stress of Polystyrene Nanoplastics in Anaerobic Digestion: Significance of the Solids Content

Effect of veterinary antibiotics on methane yield from livestock manure anaerobic digestion: an analytical review of the evidence

Contact Info

Product

Resources

About